Intermittent fasting vs CR

As we get older, our brains start to change in ways that make them increasingly vulnerable to disease – and a detailed new study of these changes points to a way some of this wear and tear might be prevented or reversed.

As we age, the composition and function of proteins in the brain change, affecting how well our brain performs later in life—influencing memory, responsiveness, and the risk of neurodegenerative diseases.

Research suggests that while cutting calories might help you lose weight and reduce risk of disease, it also carries health risks.

Nutrition & Diabetes - Late eating is associated with poor glucose tolerance, independent of body weight, fat mass, energy intake and diet composition in prediabetes or early onset type 2 diabetes

A stepping stone to good health.

Scientists at UC San Francisco have discovered a way to get rid of pancreatic cancer in mice by putting them on a high fat, or ketogenic, diet and giving them cancer therapy.

Recent research at the Institute of Molecular Biology and Biotechnology (IMBB) of the Foundation for Research and Technology-Hellas (FORTH), at the Paris Cité University, and at the University of Graz, ...

Restricting calories is known to improve health and increase lifespan, but much of how it does so remains a mystery, especially in regard to how it protects the brain. Buck Institute for Research on Aging scientists have uncovered a role for a gene called OXR1 that is necessary for the lifespan extension seen with dietary restriction and is essential for healthy brain aging.

People resort to various measures from low-carb diets and intermittent fasting to surgical procedures and medications like Ozempic in their quest for weight loss. It's a well-established fact that curbing food intake fosters healthy aging across a variety of species, humans included. Now, a recent s

Adults with obesity and nonalcoholic fatty liver disease did not see additional reductions in intrahepatic triglyceride while on a time-restricted eating regimen compared to subjects on a daily calorie-restriction diet. This is according to a recent study published in the journal JAMA Network Open and led by researchers at Southern Medical University in Guangzhou, China and colleagues in the US at Tulane University School of Public Health and Tropical Medicine in New Orleans.

Mice that fasted for 24 hours had more inflammation and were more likely to die from a bacterial infection than mice on a regular eating schedule

Nutrition researchers at the University of Illinois Chicago studied 80 people with nonalcoholic fatty liver disease and found that those who followed an alternate-day fasting diet and exercised were able to improve their health.

In a first of its kind randomized controlled trial an international team of researchers led by the Butler Columbia Aging Center at the Columbia University Mailman School of Public Health shows that caloric restriction can slow the pace of aging in healthy adults. The CALERIE intervention slowed pace of aging measured from participants' blood DNA methylation using the algorithm DunedinPACE (Pace of Aging, Computed from the Epigenome). The intervention effect on DunedinPACE represented a 2-3 percent slowing in the pace of aging, which in other studies translates to a 10-15 percent reduction in mortality risk, an effect similar to a smoking cessation intervention. The results are published online in the journal Nature Aging.

Michael Mosley has set himself a truly ambitious goal: he wants to live longer, stay younger and lose weight in the bargain. And he wants to make as few changes to his life as possible along the way. He discovers the powerful new science behind the ancient idea of fasting, and he thinks he's found a way of doing it that still allows him to enjoy his food. Michael tests out the science of fasting on himself - with life-changing results. First shown: 6 Aug 2012

Intermittent fasting—abstaining from eating for lengthy periods of time—spurs liver cells in laboratory mice to divide rapidly, according to a study led by researchers at Stanford Medicine. The finding challenges the long-standing belief that cells in the adult liver divide rarely and, when they do, primarily to repair damage to the organ. It is also the first to show an immediate effect of diet on liver cell biology.