2025 HFSP Research Grant Awardees | Human Frontier Science Program
We are ecosystems; Microbiome and more
Gut bacteria and acetate team up to cut fat in mice without muscle loss
Researchers led by Hiroshi Ohno at the RIKEN Center for Integrative Medical Sciences (IMS) in Japan have discovered a new way to reduce obesity. Their study shows that supplying the gut with extra acetate ...
Common Gut Fungus May Protect Against Fatty Liver Disease, Study Finds : ScienceAlert
There's a lot going on in the teeming microbiomes of our guts, and we're regularly making new discoveries about these bustling miniature ecosystems – including a new study identifying a symbiotic fungus that could fight liver disease.
Gut Microbe to Brain Signaling: What Happens in Vagus…
The gut microbiota has emerged as a key player in health and disease. Here we discuss the vagus nerve, which connects the visceral organs and the brai…
Gut microbiota regulates stress responsivity via the circadian system: Cell Metabolism
Gut microbes are known to modulate stress responsivity and behavior. Tofani et al.
demonstrate that such modulations occur via the circadian system. The oscillations
in gut microbiota composition regulate the diurnal rhythmicity of hypothalamic-pituitary-adrenal
(HPA)-axis function, which leads to altered stress responsivity across the day.
Frontiers | Sexual dimorphism in immunity and longevity among the oldest old
Oral Microbiome May Influence Cognitive Decline and Brain Health - Neuroscience News
The microbial ecosystems in our mouths may impact cognitive function as we age, with pathogenic bacteria linked to cognitive decline.
Eco-friendly reactor mimics lightning to produce ammonia from air and water
There's a good chance you owe your existence to the Haber-Bosch process.
Drugs targeting gut cells, not brain cells, seem to work better - Earth.com
Focusing treatments for depression and anxiety to gut cells instead of brain cells may help people feel better without side effects.
Humans are walking ecosystems and microbes rule their evolution - Earth.com
Microbes profoundly impact evolution, shaping traits alongside genes. Holobiont biology highlights how hosts and microbes form ecosystems.
Probiotics as a targeted intervention in anti-ageing: a review
The age-induced disruption of gut flora, termed gut dysbiosis, is intimately tied to compromised immune function, augmented oxidative stress and a spectrum of age-linked disorders.This review exami...
Gut Bacteria Could Hold the Key to Promoting Healthy Aging - Neuroscience News
Certain gut bacteria may play crucial roles in aging, with implications for promoting healthier aging.
Gut Bacteria Modulate Stress Responses Over Time - Neuroscience News
New research has unveiled how gut bacteria play a key role in regulating stress by interacting with circadian rhythms, opening possibilities for microbiome-based therapies for mental health.
Your showerhead and toothbrush are teeming with viruses. But don’t panic – these microbes could save lives | CNN
The warm, damp environments of your showerhead and toothbrush are the perfect breeding ground for microbes, and a new study has identified hundreds of viruses that live there, showing the vast biodiversity to be found in the average home.
Study Identifies Gut Microbe Imbalances That Predict Autism And ADHD : ScienceAlert
Years before symptoms appear.
Gut Microbiome and Aspirin May Reverse Hormonal Issues - Neuroscience News
Researchers found that mutations in the Sox3 gene cause hypopituitarism, a condition where the pituitary gland produces insufficient hormones, leading to growth issues and infertility.
Scientists uncover brain-gut connection that impairs immune defenses during psychological stress
Psychological stress disrupts communication between the brain and gut, reducing protective mucus production in the intestines. This weakens the immune system and makes the body more vulnerable to infections, but probiotics may help restore balance.
Computational tool can measure the health of a person's gut microbiome
A team of Mayo Clinic researchers has developed an innovative computational tool that analyzes the gut microbiome, a complex ecosystem of trillions of bacteria, fungi, viruses and other microorganisms ...
Healthy soils are good for your gut, brain and wellbeing – here’s why
From improving our gut microbiome to brain function, healthy and nutritious soil has lots of human health benefits.
Promising New Antibiotics Could Be Hiding in Our Gut Microbiomes : ScienceAlert
Wait, what?
Sugar Substitutes Can Wreak Havoc on Gut Microbiomes
Although some sugar substitutes can promote a healthy microbiome, most have the opposite effect. Avoiding them altogether might be best for our patients.
Resilience Linked to Healthier Brain and Gut - Neuroscience News
A new study reveals that resilient individuals show improved brain function and healthier gut microbiomes.
Link between gut microbiota and Parkinson's disease points to potential therapeutic route
A study led by Nagoya University Graduate School of Medicine in Japan has revealed a link between gut microbiota and Parkinson's disease (PD). The researchers found a reduction in the gut bacteria of ...
2024
Tetanus vaccination is associated with decreased incidence of Parkinson's disease and slower progression
Kombucha’s Microbial Magic: New Study Shows Fat-Busting Effects
The capacity of microbes to modify fat metabolism might account for potential health advantages in humans. A recent study has revealed that the microbes present in kombucha tea influence fat metabolism in the intestines of a model worm species in a way that mirrors the metabolic effects of fasting.
The gut–airway microbiome axis in health and respiratory diseases
Nature Reviews Microbiology - In this Review, Özçam and Lynch examine recent findings reporting the interaction between the gut and the airway microbiomes and explore the role of...
Gut Bacteria's Link to Alzheimer's Explored - Neuroscience News
Researchers are investigating the connection between gut bacteria and Alzheimer's disease.
Dad's Gut Bacteria Affects Child's Health - Neuroscience News
Researchers uncovered a significant link between the gut microbiota of male mice and the health and survival of their offspring.
Fermentation
A Skin-Deep Wound Can Trigger Gut Bacteria Changes
It's not just surface-level.