Oral and intranasal COVID-19 vaccines show promising results in hamster model
A new preprint discusses the protective effect of an oral adenovirus-vectored vaccine based on the SARS-CoV-2 spike against viral transmission and disease in hamsters. // 8.10.2021
BNT162b2 COVID vaccine humoral response substantially reduced after 6 months
The rollout of vaccines against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is expanding worldwide. However, little is known about the duration of protection offered by these vaccines. Real-world data on the kinetics of antibodies are beginning to appear, but a holistic picture of immunity duration is still not available. // 7.102021
COVID-19 vaccinations associated with reduction of COVID-19 infections and deaths among Medicare beneficiaries
A study identified associations between COVID-19 infections, hospitalizations, and deaths among Medicare FFS beneficiaries and the fully vaccinated population at the county level. // 7.10.2021
After 5 months, Pfizer-BioNTech COVID vaccine remains highly protective against hospitalization and death
The study "Effectiveness of mRNA BNT162b2 COVID-19 vaccine up to 6 months in a large integrated health system in the USA: a retrospective cohort study" is published in the journal The Lancet. // 7.10.2021
Acute myocarditis extremely rare after COVID mRNA vaccination in adults
Now, a new study published in the journal JAMA Internal Medicine evaluated the incidence of acute myocarditis and clinical outcomes among adults who received the mRNA vaccine in an integrated health care system in the United States. // 6.10.2021
U.S. vaccination campaign prevented up to 279,000 COVID-19 deaths
These gains, however, could be swiftly reversed by the Delta variant, which has the potential to unleash a surge of new cases among people who are unvaccinated. // 8.7.2021
Depressed seroconversion in immunocompromised COVID-19 vaccine recipients
Researchers from the University of Singapore have reviewed the data in post-vaccinated immunocompromised patients to examine the effectiveness of these vaccines in these patients. // 5.10.2021
SARS-CoV-2 mRNA vaccines elicit higher levels of antibodies compared to natural infection
Researchers from the US recently characterized the scale and specificity of SARS-CoV-2 spike-reactive antibodies from 23 participants who received SARS-CoV-2 mRNA vaccines and 10 acutely infected health care workers. // 5.10.2021
Moderna's COVID-19 vaccine proves effective against multiple SARS-CoV-2 variants, including delta
Researchers in the United States have demonstrated the real-world effectiveness of Moderna’s mRNA-1273 vaccine at protecting against infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and preventing hospitalization due to coronavirus disease 2019 (COVID-19). // 4.10.2021
J&J vaccine prevents SARS-CoV-2-induced thrombosis and inflammation in hamsters
In a recent study, researchers performed bulk RNA-Seq transcriptomic profiling of lungs from vaccinated and unvaccinated hamsters with the Janssen vaccine. // 4.10.2021
How durable is the immune response generated from the BNT162b2 vaccine?
In a recent study, researchers analyzed antibody responses to the homologous Wu strain and several other SARS-CoV-2 variants after BNT162b2 vaccination. // 4.10.2021
Vaccination reduces risk of hospitalization from all SARS-CoV-2 variants
The findings reveal that patients infected with alpha, beta, gamma, and delta variants have a higher risk of hospitalization than those infected with the original viral strain that emerged in Wuhan, China, in late December 2019. // 4.10.2021
Uuden koronasumutteen testit alkavat Suomessa ensi vuoden alussa
Suomalainen nenäsumutetta kehittävä Rokote Laboratories etenee vaiheittain testien rahoittamisessa. Uusi ankkurisijoittaja ja toimitusjohtaja lisäävät toivoa myös loppurahoituksen löytämisestä. // 1.10.2021
Biontechin johtaja: Koronarokote on mahdollisesti päivitettävä ensi vuonna
Biontechin toimitusjohtaja Ugur Sahin arvioi Financial Timesille (FT), että muokattua koronavirusrokotetta tarvittanee ensi vuoden puoliväliin mennessä. // 3.10.2021
The extent to which COVID-19 vaccination reduces transmission varies with vaccine type and SARS-CoV-2 strain
Researchers from the University of Oxford have been examining the impact of vaccination on the spread of the Alpha and Delta variants through the population. // 1.10.2021
Comparison of Pfizer, Moderna, J&J, AZ vaccines for neutralization titer, against Delta and other variants
Is one COVID vaccine better than the other? Four current vaccines — Moderna, Pfizer-BioNTech, Johnson & Johnson, and AstraZeneca — are highly effective against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), but a new medRxiv* study suggests the level of protection varies. // 30.9.2021