About vaccines

A Phase 2/3 trial of Pfizer/BioNTech's two-dose Covid-19 vaccine for children ages 5 to 11 showed it is safe and generated a "robust" antibody response. // 20.9.2021 “A Pfizer spokesperson also confirmed that were no instances of myocarditis, a type of heart inflammation that has been linked with mRNA vaccines.”

In a recent study, scientists have tested the hypothesis that indicates the role of polyP in the COVID-19 mRNA vaccine-induced immune responses. // 20.9.2021

In contrast to intramuscular vaccines, only nasal vaccines are able to block the virus in the nose by inducing local immunity in the nasal mucosa, i.e. the portal of entry and multiplication of the virus. // 18.9.2021

Nature - As debates about booster shots heat up, what’s known about the duration of vaccine-based immunity is still evolving. // 17.9.2021

A recent U.S. study concludes that getting the first dose of the COVID-19 vaccine significantly improved mental health conditions in adults. //17.9.2021

To investigate the immune memory sustainability of SARS-CoV-2-specific B cells and T cells, stimulated by the inactivated vaccine, and the potential need for a third booster dose in healthcare workers (HCWs), a non-randomized trial was undertaken by researchers at Sun Yat-sen University in Guangzhou, China. // 17.9.2021

A new study published in the preprint server medRxiv* aimed to evaluate the humoral and cellular response to COVID-19 vaccine in patients with IBD undergoing biologic or immunomodulatory therapy. // 17.9.2021

Objectives Antigen-based rapid diagnostics tests (Ag-RDTs) are useful tools for SARS-CoV-2 detection. / 16.9.2021

Objectives To investigate: (1) whether vaccine efficacy against severe COVID-19 has decreased since Delta became the predominant variant; (2) whether efficacy wanes with time since second dose. // 15.9.2021 Although there isconsiderable uncertainty attached to any extrapolation into the future, these results suggest that therapid early waning of efficacy against hospitalised COVID-19 after the second dose tapers off within afew months.

T cells control viral infection, promote vaccine durability, and in coronavirus disease 2019 (COVID-19) associate with mild disease. We investigated whether prior measles-mumps-rubella (MMR) or tetanus-diphtheria-pertussis (Tdap) vaccination elicits cross-reactive ...

Terveysviranomainen ja hoitajaliitto ovat eri mieltä siitä, pitäisikö vanhusten tai syöpäsairaiden kanssa työskenteleviltä hoitajilta edellyttää koronarokotetta. Nyt kukaan ei tiedä, kuinka moni hoitajista on ilman suojaa. //16.9.2021

Original Article from The New England Journal of Medicine — Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine through 6 Months // 15.9.2021

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An experimental one-shot COVID-19 vaccine that can be stored at room temperature provides promising results in a recent animal study. // 14.9.2021

As the number of individuals vaccinated against SARS-CoV-2 rises worldwide, population-level data regarding the vaccines' ability to reduce infection … // 14.9.2021

A collaborative team, led by principal investigator Dr. Eric Boerwinkle, at The University of Texas Health Science Center at Houston, School of Public Health is conducting a survey designed to assess the frequency of antibody-positive individuals across Texas. // 14.9.2021

A new paper in the New England Journal of Medicine reports on the effectiveness of the COVID-19 vaccines in a healthcare setting. // 14.9.2021

A Moderna phase 3 trial provides evidence that the RNA-1273 vaccine is highly effective in preventing disease following infection SARS-CoV-2. //14.9.2021

COVID-19 mRNA vaccine effectiveness among U.S. veterans remains high, even during Delta variant spread. Five Veterans Affairs Medical Centers, United States, February 1–August 6, 2021

Kaikista lääkkeistä ja rokotuksista voi tulla myös haittavaikutuksia, mutta haitat kannattaa suhteuttaa itse taudin aiheuttamiin haittoihin. // 9.9.2021

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Editorial from The New England Journal of Medicine — Covid-19 Vaccine Effectiveness and the Test-Negative Design // 8.9.2021

In this feature, we look at the side effects of each of the 22 COVID-19 vaccines that have been authorized for use in at least one country. // 6.9.2021

Scientists from the National Institutes of Health, USA, have recently demonstrated the immunogenicity and protective efficacy of two vesicular stomatitis virus (VSV)-based coronavirus disease 2019 (COVID-19) vaccines in hamsters. // 6.9.2021

The current study found that people were at a slightly higher than normal risk of blood clots after receiving Oxford-AstraZeneca and Pfizer vaccines. // 6.9.2021

//3.9.2021 The effectiveness of COVID-19 vaccines in patients with rheumatic diseases with regard to severe infection, hospitalisation, and death awaits further study, and pharmacovigilance studies will be crucial to unpick how immunological findings relate to clinical effectiveness. We have no doubt that the collaborative rheumatology community will continue to address and answer these outstanding questions.

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Rokottamattomien keskuudessa koronan ilmaantuvuus on jopa yhdeksän kertaa korkeampi kuin rokotettujen. // 3.9.2021