New research examined SARS-CoV-2 and its impact on oral health and suggests that survival against the infection may be partially dependent on such factors. // 1.12.2021
Risk factors for developing COVID-19: a population-based longitudinal study (COVIDENCE UK)
Background Risk factors for severe COVID-19 include older age, male sex, obesity, black or Asian ethnicity and underlying medical conditions. Whether these factors also influence susceptibility to developing COVID-19 is uncertain. Methods We undertook a prospective, population-based cohort study (COVIDENCE UK) from 1 May 2020 to 5 February 2021. Baseline information on potential risk factors was captured by an online questionnaire. // 30.11.2021
Increased illness burden of COVID-19 among unvaccinated first responders
A new study gathered data from the HEROES-RECOVER prospective cohorts and reported an increased illness burden of COVID-19 among unvaccinated first responders.// 30.11.2021
LRRC15 is an inhibitory receptor blocking SARS-CoV-2 spike-mediated entry in trans
SARS-CoV-2 infection is mediated by the entry receptor ACE2. Although attachment factors and co-receptors facilitating entry are extensively studied, cellular entry factors inhibiting viral entry are largely unknown. // 29.11.2021
How often does SARS-CoV-2 infect alongside another viruses?
Researchers have been exploring data from COVID-19 patients tested at hospitals or clinics that also look for evidence of other diseases. // 28.11.2021
Study shows plasmacytoid dendritic cells may be a viable target for protection against SARS-CoV-2
A recent research paper by scientists from Denmark reveals that circulating plasmacytoid dendritic cells may be a potential therapeutic target to maintain desired levels of an antiviral compound known as interferon, allowing for the mitigation of coronavirus disease (COVID-19) severity. // 28.11.2021
Seroprevalence study reveals high exposure to SARS-CoV-2 in Bangui population
Researchers performed a cross-sectional study in the city of Bangui, the capital of the Central African Republic from July 12, 2021, to August 20, 2021. // 28.11.2021
Koronavirus | ”Tiivis läiskä” paljastaa, että nyt on tosi kyseessä – Suomalaisen rokottamattoman koronapotilaan keuhkokuvat näyttävät tuhon, jonka rinnalla tupakointi on lastenleikkiä
HS:n haltuunsa saamat keuhkokuvat kertovat karusta taistelusta, jota suomalaissairaaloiden teho-osastoilla nyt käydään. Kokenut radiologi kertoo, mitä muutokset keuhkoissa merkitsevät. // 28.11.2021
Immune dysregulation and immunopathology induced by SARS-CoV-2 and related coronaviruses — are we our own worst enemy?
Nature Reviews Immunology - In this Perspective, Lok-Yin Roy Wong and Stanley Perlman consider how severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and related coronaviruses are able to... // 26.11.2021
A study published in the journal Royal Society Open Science demonstrates the critical role of timely intervention in New Zealand's success story. The researchers used a stochastic branching process model to simulate the trajectory of COVID-19 transmission and control during New Zealand's 2020 outbreak. They calculated the number of reported cases and deaths and the probability of elimination within a defined time frame. // 25.11.2021
Study explores adverse effects of SARS-CoV-2-induced antibody responses
The authors of a research paper published in the journal Frontiers in Immunology used Sandwich ELISA tests to determine the distribution of IgG sub-classes and complement activation levels in plasma from convalescent individuals. // 25.11.2021
A review of natural immunity, vaccines, and variants in SARS-CoV-2 reinfection
In a literature review article published in the Journal of Community Hospital Internal Medicine Perspectives, authors from the US performed a thorough investigation of previous studies and case reports of SARS-CoV-2 reinfection. This review discusses the role of natural immunity, vaccines, and SARS-CoV-2 variants in reinfection. // 25.11.2021
SARS-CoV-2 reinfection and the natural immune response
Researchers review available literature on immunity and SARS-CoV-2 infection to elucidate mechanisms behind SARS-CoV-2 immunity and reinfections. // 24.11.2021
Strong antibody responses against harmless coronaviruses may protect against SARS-CoV-2
Infections with the novel coronavirus and vaccination lead to strong antibody responses against SARS-CoV-2. Immune responses to other human coronaviruses, which mostly only cause harmless colds, also provide some protection against SARS-CoV-2. // 23.11.2021
SARS-CoV-2 moves between permissive cells and non-permissive neuronal cells via tunneling nanotubes (TNT)
Scientists investigate the neuroinvasive potential of SARS-CoV-2 and the role of tunneling nanotubes (TNTs) in spreading the infection to neighboring cells. // 23.11.2021
A new study focused on estimating the temporal dynamics of transmissibility of infected cases in the absence of intervention measures (unmitigated generation interval). // 24.11.2021
Relaxation of COVID-19 restrictions led to the reemergence of seasonal respiratory viruses in Houston
A Houston Methodist study showed a rapid return of seasonal respiratory viruses after COVID-19 restrictions were relaxed in Texas, demonstrating the effectiveness of masking, distancing and other precautionary measures at stopping the spread of many respiratory illnesses, not just COVID-19. // 24.11.2021
Mouthwash containing an antiviral phthalocyanine derivative shortens hospitalizations due to COVID-19
In a study published in the journal Scientific Reports, a research group from Brazil showed how antiviral anionic phthalocyanine derivative used in a mouthwash protocol may not only reduce the symptoms of coronavirus disease (COVID-19), but also hamper the spread of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). // 23.11.2021
Study shows SARS-CoV-2 can infect and replicate in human iPSC-derived neurons
In a study recently published on the bioRxiv preprint server, researchers attempted to further increase the scope of previous studies in examining SARS-CoV-2 infection of human CNS resident cells. // 22.11.2021