Interferon beta versus the SARS-CoV-2 Delta variant
In a study recently published on the bioRxiv* preprint server, researchers investigated the difference in replication efficiency or IFN sensitivity of the four VOCs. // 22.11.2021
IFITM proteins are important replication cofactors for SARS-CoV-2, including Delta variant
In a study recently published on the bioRxiv* preprint server, researchers investigated the IFITM2 dependency of SARS-CoV-2 VOCs, including the delta variant for efficient infection. // 22.11.2021
Preexisting rhinovirus infection and IFN induction in epithelium of asthma patients decreases SARS-CoV-2 infection
In a recent study, researchers explored the effects of RV, HDM, and SARS-CoV-2 on differentiated primary human bronchial epithelial cells (HBECs) in vitro and in experimental in vivo RV infection in healthy subjects and asthmatic patients. // 22.11.2021
Characterization of B-cell receptor repertoires in COVID-19 patients
In a new study published in the journal Human Immunology, scientists sought to better understand how B-cell immune repertoire changes over time during SARS-CoV-2 infection by comprehensively characterizing the dynamics of immunoglobin heavy chain (IGH) repertoire in COVID-19 patients. // 22.11.2021
Now, a new study published in the journal IEEE Access seeks to better understand the dynamics of the spread of COVID-19 and evaluates the evidence of its chaotic behavior in the US and globally using a compartmental model. // 22.11.2021
COVID-19 multistate outbreak associated with large public gatherings
Researchers from the Centers for Disease Control have investigated a case in Massachusetts that showed a high proportion of vaccine breakthrough infections. // 22.11.2021
Bioinformatics analysis identifies pathways involved in intestinal SARS-CoV-2 infection
Researchers recently used bioinformatics analysis techniques to explore the diseases caused by SARS-CoV-2 infection in the human digestive tract. // 22.11.2021
Population-based risk compensation may have been a driving force in UK's COVID pandemic
The COVID-19 pandemic has irreversibly altered our lives in many ways. However, available COVID vaccines are effective against (symptomatic) severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, hospitalizations, and even death. // 19.11.2021
Seroprevalence study in Tamil Nadu shows antibody decline following SARS-CoV-2 infection and vaccination
In the sixth-most populated state of India – Tamil Nadu, three rounds of a district-level serological study were conducted through two COVID waves. // 18.11.2021
Severe COVID-19 patients have significantly higher NK and T cell frequency
A new study published in the open-access journal Cells aimed to clarify the role of NK and T cell subsets in SARS-CoV-2 infection in hospitalized COVID-19 patients to unravel their potential association with disease severity. // 18.11.2021
Air filter and floor sampling to detect SARS-CoV-2 RNA in schools
A study recently published on the medRxiv* preprint server observed the presence of SARS-CoV-2 RNA in five schools (96 classrooms) in Davis, California (USA), by collecting weekly surface-swab samples from classroom floors and/or portable high-efficiency particulate air (HEPA) units. // 18.19.2021
Efficacy of UVC light prototype devices for inactivating SARS-CoV-2
Researchers examined the efficacy of UVC light prototype devices to understand the duration and wavelength of UVC radiation needed for SARS-CoV-2 inactivation. // 17.11.2021
Excess mortality reveals infection speed in COVID-19 is low with seasonal infection patterns and escape variants
Researchers from the University of Wurzburg in Germany have been attempting to create a new method for determining the R0 using excess mortality data. // 18.11.2021
Study shows neutralizing capacity of monoclonal antibodies against SARS-CoV-2 variants of concern
Canadian public health researchers recently published a study in the journal Antiviral Research wherein they described generating a panel of murine hybridomas recognizing SARS-CoV-2 spike protein or nucleoprotein, capable of neutralizing the SARS-CoV-2 variants of concern, proving their therapeutic potential. // 17.11.2021
A new study describes the cases and outbreaks of COVID-19 in schools and preschools in Norway to evaluate the strategy of keeping them open with control measures in place. // 18.11.2021
AstraZeneca's antibody drug over 80% effective at preventing Covid, trial shows
AstraZeneca's antibody treatment has been shown to be highly effective at preventing Covid in people who may not respond well to vaccines. // 18.11.2021
Benefits of vaccine mandates and vaccine passports for SARS-CoV-2
A new study has been published that evaluates the benefits of VMVP by estimating the benefits of vaccination and exclusion of unvaccinated people from different settings. // 16.11.2021
Air filtration device removes almost all traces of airborne SARS-CoV-2
When a team of doctors, scientists and engineers at Addenbrooke's Hospital and the University of Cambridge placed an air filtration machine in COVID-19 wards, they found that it removed almost all traces of airborne SARS-CoV-2. // 17.11.2021
New atomic-level insight of SARS-CoV-2 within a respiratory aerosol
In a paradigm-shifting paper currently available on the bioRxiv* preprint server, the researchers have dramatically extended the possibilities of computational microscopy in order to better understand both structure and dynamics of respiratory aerosols laden with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). // 16.11.2021
Study identifies a host factor that reflects different levels of inflammation within mild COVID-19 cases
A new study investigates serum from COVID-19 convalescents and uninfected individuals to determine the molecular mechanisms of host responses. // 15.11.2021
Prescription omega-3 pill did not reduce hospitalization or death from COVID-19
A high dose of a purified omega-3 fatty acid, available by prescription only, was well tolerated; however, it did not substantially reduce incidents of hospitalizations and/or deaths among people with COVID-19, according to a late-breaking clinical trial presented today at the American Heart Association's Scientific Sessions 2021. // 15.11.2021
Deficient spike-specific T cell responses and inability to neutralize SARS-CoV-2 variants 12 month post-infection
Researchers conducted a comprehensive, longitudinal, long-term immune study, including functional assays to assess immune fitness against antigenically different VoC. The study is currently available on the preprint server medRxiv* while awaiting peer review. // 15.11.2021
COVID-19 vaccines more protective than ‘natural’ immunity
A new study concludes that a COVID-19 mRNA vaccine is around five times more effective at preventing hospitalization than a previous SARS-CoV-2 infection. 5.11.2021
Unexposed populations and potential COVID-19 burden in European countries
We estimate the potential remaining COVID-19 burden in 19 European countries by estimating the proportion of each country’s population that has acquired immunity to severe disease through infection or vaccination. // 10.11.2021