Corona in general

Major cell entry factors of SARS-CoV-2 are present in neurons; however, the neurotropism of SARS-CoV-2 and the phenotypes of infected neurons are still unclear. Acute neurological disorders occur in many patients, and one-third of COVID-19 survivors suffer from brain diseases. // 1.2.2022

In a new study, researchers aimed to understand and improve the changing COVID-19 evidence over time regarding three important review questions using a living systematic review. // 1.2.2022

The current study showed a marked decrease in disease severity with Omicron compared to the Delta variant. // 31.1.2022

In a new study, researchers found that nucleocapsid antigen in the blood (antigenemia) is a sensitive and specific biomarker for acute coronavirus disease 2019 infection. // 31.1.2022

Researchers recently published a study to address this knowledge gap and understand the scope of the personal impact on patients and their daily lives due to delayed surgeries. // 31.1.2022

This unique paper compares neurosurgical patients with COVID-19 for perioperative complications to those without COVID-19. // 31.1.2022

Researchers evaluate antibody responses in vaccinated individuals who subsequently developed Delta and Omicron SARS-CoV-2 breakthrough infections. // 30.1.2022

Researchers demonstrate how cytotoxic T-lymphocytes (CTLs) with specificity for SARS-CoV-2 eliminate multiple infected targets. // 30.1.2022

SARS-CoV-2 variants are emerging at frequent intervals with an ability to transmit faster and evade the immune responses. Most of Indian adults have received one or two doses of vaccination and, have also been infected naturally during the first and second waves. // 29.1.2022

Nature - Human genetic and immunological determinants of critical COVID-19... // 28.1.2022

In a 38-year-old man who manifested mild symptoms of COVID-19 for 20 days, the novel coronavirus continued to be detected in his organism and to undergo mutations for 232 days. // 27.1.2022

Palliative care conversations have taken on a new meaning during the pandemic // 27.1.2022

Early registry data showed COVID cases accounted for 7% of lung transplants nationwide // 27.1.2022

Computer analysis of human brain immune components showed that NRP1 and furin were significantly expressed in neuronal cells, suggesting that NRP1 may have a role in SARS-CoV-2 neuropathology. // 27.1.2022

Scientific Reports - COVID-19 reinfections among naturally infected... // 26.1.2022

New study findings indicated that some hematological alterations that occur during COVID-19-related hospital admission were associated with an increase in the risk of COVID-19-associated ICU admission and mortality. // 26.1.2022

A new study, published on the medRxiv preprint server, focused on the production of human CD4+ T cell lines (TCLs), reactive to either S or M protein, and analyzed if the S and M structural proteins had intrinsic differences in driving antigen-specific CD4+ T cell responses. // 27.1.2022

Researchers assess the probability of T-cell apoptosis in patients with severe COVID-19 who were admitted to the hospital. // 26.1.2022

A new study investigated SARS-CoV-2 spike protein responses targeted by cross-reactive T cells that were isolated from convalescent COVID-19 individuals along with previously uninfected donors. // 25.1.2022

In a new study, a team of researchers reviewed the published literature to find evidence for humoral SARS-CoV-2 correlate of protection (CoP). // 25.1.2022

Many experts now predict that COVID-19, which so far has killed more than 5.5 million people worldwide, will remain endemic as new, infectious variants of SARS-CoV-2 emerge. // 25.1.2022

A new study describes the finding that patients of COVID-19 exhibit large amounts of focal β-amyloid deposits in their neocortical tissues. // 25.1.2022

A new study looks at the molecular level inhibition of the protective CFTR gene by the SARS-CoV-2 spike protein. // 26.1.2022

Nature - Rosy assumptions endanger public health — policymakers must act now to shape the years to come. // 24.1.2022

In a new study, exhaled aerosols were compared between infected SARS-CoV-2 patients and healthy controls for the first time. // 25.1.2022

Researchers from the University of London have been exploring the case-fatality rate of COVID-19 in the top-vaccinated countries compared to the rest of the world. // 25.1.2022

A new study aimed to study the incidence of SARS-CoV-2 infections in orchestra and choir musicians compared to controls. // 24.1.2022

In a new study, researchers conducted an analysis of databases that have information on the transcriptomic and proteomic expression of ACE2, TMPRSS2, NRP1, and furin in several human brain areas. // 24.1.2022

Scientists focused on determining the prevalence of OD eighteen months after COVID-19 infection. // 24.1.2022

A new study discusses the importance of single nucleotide polymorphisms in the Rab46 gene as a marker of adverse outcomes in high-risk COVID-19 patients. // 23.1.2022