Respiratory muscle dysfunction in long-COVID patients - PubMed
Our findings point towards respiratory muscle dysfunction as a novel aspect of COVID-19 sequelae. Thus, we strongly advocate for systematic respiratory muscle testing during the diagnostic workup of persistently symptomatic, convalescent COVID-19 patients. // 16.5.2022
30% of COVID Patients in Study Developed 'Long COVID'
The UCLA researchers studied 1038 people enrolled in the UCLA COVID Ambulatory Program between April 2020 and February 2021. Researchers found that 309 of them developed long COVID. // 21.4.2022
Cardiac impairment in Long Covid 1-year post-SARS-CoV-2 infection
Background Long Covid is associated with multiple symptoms and impairment in multiple organs. Cardiac impairment has been reported to varying degrees by varying methodologies in cross-sectional studies. Using cardiac magnetic resonance (CMR), we investigated the 12-month trajectory of cardiac impairment in individuals with Long Covid. // 4.4.2022
Prof Jeremy Nicholson: the link between Long Covid and heart disease
Professor Jeremy Nicholson is the Director of the Australian National Phenome Centre at Murdoch University and a leading researcher into Long Covid. His team is working with multiple universities around the world - including Harvard and Cambridge - to try and understand the long term cardiometabolic and other systemic effects of the disease, as well as the impact of Covid-19 in kids. // 2.4.2022
More Evidence COVID 'Brain Fog' Is Biologically Based
Patients with 'brain fog' during acute COVID-19 had the highest levels of inflammatory markers, offering additional evidence of a neurological basis for post-acute sequelae of SARS-CoV-2 infection. // 1.4.2022
Risk factors and preventive interventions for post Covid-19 condition: systematic reviews
Background The Covid-19 outbreak has presented many challenges to governments and healthcare systems, including observations of symptoms that persist beyond acute infection labelled as post Covid-19 condition. // 25.3.2022
Different Variants May Cause Different Long COVID Symptoms: Study
Long COVID patients who were infected with the Alpha variant of SARS-CoV-2 showed more neurological, cognitive, and emotional problems than those who were infected with the original (wild-type/Wuhan) variant. // 25.3.2022
Long-term symptoms after SARS-CoV-2 infection in a cohort of hospital employees: duration and predictive factors
Objective: To evaluate the frequency, duration and patterns of long-term coronavirus disease 2019 (COVID-19) symptoms and to analyze risk factors for long-lasting COVID-19 sequelae among hospital employees (HEs). // 22.3.2022
Multi-organ impairment and Long COVID: a 1-year prospective, longitudinal cohort study
Importance: Multi-organ impairment associated with Long COVID is a significant burden to individuals, populations and health systems, presenting challenges for diagnosis and care provision. Standardised assessment across multiple organs over time is lacking, particularly in non-hospitalised individuals. // 21.3.2022
A Case Of Shrunken Brains: How Covid-19 May Damage Brain Cells
Comparing brain volume before and after individuals were exposed to SARS-CoV-2, this study documents significant cortical gray matter loss, equivalent to nearly 10 years of aging. // 21.3.2022
Study reports persistent SARS-CoV-2 lingering within tissues of patients with long COVID
Researchers investigated whether residual SARS-CoV-2 antigens and RNA are present in tissues samples of long COVID-19 patients beyond the convalescent phase of COVID-19. //24.2.2022
COVID-19 and Mitochondrial Non-Coding RNAs: New Insights From Published Data
Scientists all around the world are working to investigate new ways to prevent and treat COVID-19, and recent research has been focusing on the effects of a syndrome commonly called “long COVID.” People affected by this syndrome usually suffer from symptoms like the ones observed in several types of fatigue syndrome. As these syndromes are often linked to mitochondrial dysfunction, researchers hypothesized that a dysfunction in the mitochondrial metabolism might be part of the causes of long COVID. // 4.2.2022
Long COVID: post-acute sequelae of COVID-19 with a cardiovascular focus
Abstract. Emerging as a new epidemic, long COVID or post-acute sequelae of coronavirus disease 2019 (COVID-19), a condition characterized by the persistence of… // 18.2.2022
We explore what we know so far about risk factors for long COVID, a syndrome characterized by COVID-19 symptoms lasting weeks or months after the initial illness. // 17.2.2022
Study determines 115 long COVID symptoms and their associated risk factors
A new study determined which symptoms are linked with confirmed SARS-CoV-2 infection beyond 12 weeks post-infection in non-hospitalized individuals, and investigated the associated risk-factors of such symptoms. // 17.2.2022
Many women with long COVID who experience COVID-19 symptoms for months have reported changes in their menstrual cycles. What does this mean for them? // 16.2.2022
SARS-CoV-2-specific T cells associate with reduced lung function and inflammation in pulmonary post-acute sequalae of SARS-CoV-2
As of January 2022, at least 60 million individuals are estimated to develop post-acute sequelae of SARS-CoV-2 (PASC) after infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). While elevated levels of SARS-CoV-2-specific T cells have been observed in non-specific PASC, little is known about their impact on pulmonary function which is compromised in the majority of these individuals. // 15.2.2022
Neurological issues, ranging from memory lapses to trouble with attention, have been widely reported after recovery from severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) infection. Unfortunately, there is limited information about pathways to recovery after severe COVID hospitalization. Now, a prospective study of 4,491 patients hospitalized with COVID suggests neurological recovery can take at least a year. // 13.2.2022