{Treatment of stored wheat grain} {PureLine chlorine dioxide used} "Mode of Action of chlorine dioxide against insect pests •Oxidative stress--ClO2 enhances the production of reactive oxygen species (ROS) inside larvae of Tribolium castaneumand Plodiainterpunctella. It also causes more antioxidant enzymes (superoxide dismutase and thioredoxin-peroxidase) being synthesized by gene up-regulation. However excess ROS eventually accumulates and imposes oxidative stress to cells, which leads to the lethal effect."