Airborne Causes of Disease

Airborne Causes of Disease

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Mounting evidence suggests coronavirus is airborne — but health advice has not caught up
Mounting evidence suggests coronavirus is airborne — but health advice has not caught up
"People infected with SARS-CoV-2 exhaled 1,000–100,000 copies per minute of viral RNA, a marker of the pathogen’s presence. Because the volunteers simply breathed out, the viral RNA was probably carried in aerosols." "When researchers created aerosols of the new coronavirus, the aerosols remained infectious for at least 16 hours, and had greater infectivity than did those of the coronaviruses SARS-CoV and MERS-CoV." "No amount of ventilation could have reduced the risk to an acceptable level for the two-and-a-half-hour rehearsal, she says." "SARS-CoV-2 in mock saliva aerosols lost 90% of its viability in 6 minutes of exposure to summer sunlight, compared with 125 minutes in darkness."
·nature.com·
Mounting evidence suggests coronavirus is airborne — but health advice has not caught up
SARS-CoV-2 is transmitted via contact and via the air between ferrets | Nature Communications
SARS-CoV-2 is transmitted via contact and via the air between ferrets | Nature Communications
"SARS-CoV-2 was also found to be transmitted via the air in two out of six ferrets21, and in two out of six cats. However, only low levels of SARS-CoV-2 RNA were detected in nasal washes and feces of the indirect recipient ferrets, and no infectious virus was isolated21. Furthermore, virus shedding was shorter as compared to the donor animals and only one out of the two SARS-CoV-2 RNA positive indirect recipient ferrets seroconverted. Similarly, the transmission via the air between cats was not efficient. " "No SARS-CoV-2 RNA was detected in the air sampled in three isolation rooms, or 10 cm from a symptomatic patient who was breathing, coughing or speaking. Nevertheless, RNA was detected on the air exhaust outlet of one of the isolation rooms in the first study, suggesting that virus-laden droplets may be displaced by airflows."
·nature.com·
SARS-CoV-2 is transmitted via contact and via the air between ferrets | Nature Communications
Drivers of airborne human-to-human pathogen transmission - PubMed
Drivers of airborne human-to-human pathogen transmission - PubMed
Airborne pathogens - either transmitted via aerosol or droplets - include a wide variety of highly infectious and dangerous microbes such as variola virus, measles virus, influenza A viruses, Mycobacterium tuberculosis, Streptococcus pneumoniae, and Bordetella pertussis. Emerging zoonotic pathogens, …
·pubmed.ncbi.nlm.nih.gov·
Drivers of airborne human-to-human pathogen transmission - PubMed
Influenza A virus is transmissible via aerosolized fomites | Nature Communications
Influenza A virus is transmissible via aerosolized fomites | Nature Communications
We provide evidence of a mode of transmission seldom considered for influenza: airborne virus transport on microscopic particles called “aerosolized fomites.” In the guinea pig model of influenza virus transmission, we show that the airborne particulates produced by infected animals are mainly non-respiratory in origin. Surprisingly, we find that an uninfected, virus-immune guinea pig whose body is contaminated with influenza virus can transmit the virus through the air to a susceptible partner in a separate cage. We further demonstrate that aerosolized fomites can be generated from inanimate objects, such as by manually rubbing a paper tissue contaminated with influenza virus. Our data suggest that aerosolized fomites may contribute to influenza virus transmission in animal models of human influenza, if not among humans themselves, with important but understudied implications for public health.
·nature.com·
Influenza A virus is transmissible via aerosolized fomites | Nature Communications