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Methods, Systems and Devices for Administration of Chlorine Dioxide - Google Patents [abandoned]
Methods, Systems and Devices for Administration of Chlorine Dioxide - Google Patents [abandoned]
****!!!!*** "Devices, compositions, systems and methods for the non-cytotoxic delivery of chlorine dioxide to a tissue." "Cytotoxicity of chlorine dioxide-containing compositions results predominantly from the presence of oxy-chlorine anions, and not from the presence of chlorine, which can be a product of chlorine dioxide decomposition." " mucosal tissue, epidermal tissue, dermal tissue, and subcutaneous tissue (also called hypodermis tissue). Mucosal tissue includes buccal mucosa, other oral cavity mucosa (e.g., soft palate mucosa, floor of mouth mucosa and mucosa under the tongue), vaginal mucosa and anal mucosa... Biological tissue may be intact or may have one or more incisions, lacerations or other tissue-penetrating opening.” "tooth enamel, dentin, fingernails, toe nails, hard keratinized tissues and the like, found in animals" "In some embodiments, the method is practiced on a chronic wound of soft tissue"
·patents.google.com·
Methods, Systems and Devices for Administration of Chlorine Dioxide - Google Patents [abandoned]
Harmful effects of chlorine dioxide exposure
Harmful effects of chlorine dioxide exposure
****!!!!**** 2020 "reports of adverse effects (gastrointestinal symptoms, dehydration, hypotension) [1,2]. Published case reports also describe CD toxicities including methemoglobinemia, hemolytic anemia, toxic irritant dermatitis and Kikuchi-Fujimoto disease" "majority of exposures represent acute toxicity (45/53, 84.9%), as most effects occurred immediately or ≤24 h of exposure (40/53, 75.5%). Thirteen patients (24.5%) were hospitalized. Two critical care unit admissions included significant electrolyte abnormalities, electrocardiogram changes, and altered mental status. Both patients recovered after electrolyte and fluid repletion. We suspect these clinical effects were driven by significant electrolyte loss linked to the gastrointestinal effects of CD"
·ncbi.nlm.nih.gov·
Harmful effects of chlorine dioxide exposure