" This is only the second case of sodium chlorite intoxication reported in the medical literature and the first to report the use of renal replacement therapy in combination with red cell exchange in its management. "

The availability of safe and effective antimicrobials is relatively recent. Many infections that we now expect to cure once inflicted considerable mor…

Background is provided on biofilms, including their formation, tolerance mechanisms, structure, and morphology within the context of chronic wounds. The features of biofilms in chronic wounds are discussed in detail, as is the impact of biofilm on wound ...

Abstract. Biofilms play a pivotal role in healthcare-associated infections, especially those related to the implant of medical devices, such as intravascular c

****!!!!*** "Subchronic toxicities of ClO2, NaClO2, NaClO3 and NH2Cl were studied in the African Green monkeys (Cercopithecus aethiops). The chemicals were administered in drinking water during 30-60 days subchronic rising dose protocols. The only unexpected and significant toxic effect was elicited by ClO2; this chemical inhibited thyroid metabolism in the animals at a dose of ca. 9.0 mg/kg/day. A statistically significant decrease of serum thyroxine occurred after the fourth week of exposure to 100 mg/l.concentration. The extent of thyroid suppression was dose dependent in each individual monkey, and was reversible after cessation of exposure. NaClO2 and NaClO3 failed to elicit similar effects in doses up to ca. 60 mg/kg/day. Also, NaClO4 or NH2Cl did not cause T-4 suppression in doses of 10 mg/kg/day. The selective thyroid effect of ClO2 was unexplained and it appeared to be paradoxical since ClO2 was rapidly reduced by the oral and gastric secretions to nonoxidizing species (presumably Cl-). No evidence of thyroid effects were detected in the serum of human volunteers who ingested approximately 1 mg/l. of ClO2 in drinking water as a result of routine use in the community water treatment process. Sodium chlorite induced dose-dependent oxidative stress on hematopoesis, causing decreased hemoglobin and red cell count and increased methemoglobin content. At the same time, serum transaminase (SGPT) levels showed significant subclinical elevation. The hematologic effects of NaClO2 rebounded during exposure indicating compensatory hemopoietic activity taking effect during oxidative stress. Sodium chlorate and chloramine did not induce detectable hematologic changes in the animals."

In separate subchronic toxicity studies, male and female Sprague-Dawley rats received three water disinfectants in the drinking water for 90 consecutive days. he treatment levels were 25 mg/L, 100 mg/L, 175 mg/L and 250 mg/L for chlorine, and 25 mg/L, 50 mg/L, 100 mg/L and 200 mg/L for both monochloramine and chlorine dioxide. ontrols received carbonated (ph buffered) drinking water. ater consumption for all three compounds decreased in a dose-related fashion with increasing concentration of disinfectant, most likely due to unpalatability. one of the disinfectants caused premature deaths in...

***EXTREMELY relevant in designing safety evaluations for airborne uses in occupied areas

health effects of disinfection by-products concerning cancer, reproduction and development

Authors: Norio Ogata* (Taiko Pharmaceuticals--mail: nogata7@yahoo.co.jp), Tomoko Koizumi and Fumihiro Ozaw

[Investigation on an accident of chlorine dioxide poisoning]

Crisp-maker Walkers and a chemical distributor are fined £350,000 after the death of a worker from gas poisoning.

Free radicals are unstable atoms that can cause damage to cells and lead to illnesses and the aging process. Exactly what impact do they have on the body? This MNT Knowledge Center article look at the free radicals and how antioxidants interact with them, as well as what causes them to develop.

{Includes several erroneous statements about CD.} What Does Research Have to Say About HBOT and ASD? Throughout human history, the helping professions – medicine, psychology, education – have operated under many ethical guidelines and codes of conduct. But one singular, defining, and unwavering principle has been, do no harm. Providers of services understand that, fundamentally, we cannot behave in ways that will harm – physically, psychologically, or otherwise – the people whom we serve. This is part of the “DNA” of medical and social services. This

{abstract only}

{Doc says Sodium Chlorite has severe damaging health effects & references studies. Refers to Sodium Chlorite and Chlorous Acid & Sodium Salt as synonyms}

{Mentions many safety level tests with data}

2002

{Includes references to CD exams by various agencies} Following a request from the European Commission, the risks to human health related to the presence of chlorate in food were assessed by the EFSA Panel on Contaminants in the Food Chain (CONTAM Panel...

1981 study. Authors: Lubbers, Chauhan, Bianchine

Obscure tests on Chlorine Dioxide effects on humans

"The efficacy and safety of UC-1 were evaluated. The antimicrobial activity was more than 98.2% reduction when UC-1 concentrations were 5 and 20 ppm for bacteria and fungi, respectively. The half maximal inhibitory concentrations (IC50) of H1N1, influenza virus B/TW/71718/04, and EV71 were 84.65 ± 0.64, 95.91 ± 11.61, and 46.39 ± 1.97 ppm, respectively. A 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) test revealed that the cell viability of mouse lung fibroblast L929 cells was 93.7% at a 200 ppm UC-1 concentration that is over that anticipated in routine use. Moreover, 50 ppm UC-1 showed no significant symptoms in a rabbit ocular irritation test. In an inhalation toxicity test, treatment with 20 ppm UC-1 for 24 h showed no abnormality and no mortality in clinical symptoms and normal functioning of the lung and other organs. A ClO2 concentration of up to 40 ppm in drinking water did not show any toxicity in a subchronic oral toxicity test. Herein, UC-1 showed favorable disinfection activity and a higher safety profile tendency than in previous reports."

{Good description of CD actions } Particular info for objects containing electronics. Find more information today.

EPA evaluates the potential risks of the manufacture and use of thousands of chemicals. To assist with this evaluation, EPA scientists developed a rapid, automated model using off the shelf technology that predicts exposures for thousands of chemicals.

Over the past 10 years, there have been hundreds of accidents involving chlorine nationwide, injuring thousands

Oxidation of diclofenac with chlorine dioxide in aquatic environments: influences of different nitrogenous species

Request PDF | Reactions of Tetracycline Antibiotics with Chlorine Dioxide and Free Chlorine | Tetracyclines (TCs) are a group of widely used antibiotics that have been frequently found in the aquatic environment. The potential reactions of... | Find, read and cite all the research you need on ResearchGate