ATC Malachlorite® for treatment of patients with acute Plasmodium falciparum infection: A pilot study incorporating 500 patients in the rural area of Cameroon
Malaria is one of the most widespread infectious diseases with over 2 million deaths per year in Central Africa. Since new drug combinations are characterized by the development of tolerance as well as serious side effect there is an increasing demand for a new medication. We therefore set out to study the efficacy of a sublingual tablet with a new mode of action consisting of sodium chlorite (NaClO2) plus citric acid and an artimisin extract. By adding sodium bicarbonate, an effervescent composition is attained, which when being exposed to saline, chlorine dioxide (ClO2) the active ingredi...