The effects of chronic administration of chlorine dioxide, chlorite and chlorate to normal healthy adult male volunteers - PubMed
The physiological impact of chronic 12 week ingestion of chlorine dioxide and its byproducts, chlorite and chlorate, was compared to the effects of chlorine, chloramine and untreated water. The water disinfectant solutions were administered daily (500 ml, 5 ppm) to normal healthy adult male voluntee …
Sodium chlorite administration in long-evans rats: Reproductive and endocrine effects
Long-Evans rats, 4–6 weeks of age, were given access to 0, 1, 10, or 100 ppm sodium chlorite in deionized water ad libitum as drinking water. Males we…
Controlled clinical evaluations of chlorine dioxide, chlorite and chlorate in man
To assess the relative safety of chronically administered chlorine water disinfectants in man, a controlled study was undertaken. The clinical evaluat…
Effect of chlorine dioxide and its metabolites in drinking water on fetal development in rats
The chlorination of surface waters is known to form trihalomethanes. Therefore, chlorine dioxide (ClO2) is being considered as an alternative disinfectant. This study was designed to determine the ef...
Effect of chlorine dioxide and metabolites on glutathione dependent system in rat, mouse and chicken blood - PubMed
Chlorine dioxide (Cl02) has been proposed as an alternative disinfectant to chlorine to avoid formation of organohalides. Cl02 and metabolites, chlorite (Cl0-2) and chlorate (Cl0-3) in drinking water produced decreases in rat and chicken blood GSH. The GSH dependent system was studied in rat and chi …
Effects of the acute rising dose administration of chlorine dioxide, chlorate and chlorite to normal healthy adult male volunteers - PubMed
Chlorine dioxide is under consideration for use as a water disinfectant alternative to chlorination in the United States. A rising dose tolerance study was undertaken to assess the relative safety and tolerance of acute administration of chlorine dioxide and its byproducts, chlorite and chlorate, to …
Mechanistic aspects of ingested chlorine dioxide on thyroid function: impact of oxidants on iodide metabolism.
Toxicological studies dealing with recent findings of health effects of drinking water disinfectants are reviewed. Experiments with monkeys and rodents indicate that the biological activity of ingested disinfectants is expressed via their chemical interaction ...
EFSA CONTAM Panel (EFSA Panel on Contaminants in the Food Chain), Chlorate metabolized to Chlorite in rats -2015.Scientific Opinion on risks for public health related to the presence of chlorate in food
Oxidative damage to the erythrocyte induced by sodium chlorite, in vivo | Request PDF
Request PDF | Oxidative damage to the erythrocyte induced by sodium chlorite, in vivo | The ability of sodium chlorite to react with constituents of the erythrocyte, in vitro, was examined and compared to that of nitrite. The... | Find, read and cite all the research you need on ResearchGate
(PDF) Studies of Carcinogenicity of Sodium Chlorite in B6C3F1 Mice
PDF | The carcinogenic activities of sodium chlorite in B6C3F1 mice were examined. Sodium chlorite was given at concentrations of 0 (control), 0.025%... | Find, read and cite all the research you need on ResearchGate
(PDF) [Teratogenicity study of sodium chlorite in rats by oral administration]
PDF | The teratogenicity of sodium chlorite (NaClO2) was assessed in Wistar rats (Crj: Wistar). Sodium chlorite dissolved in distilled water was given... | Find, read and cite all the research you need on ResearchGate
Toxicity from the Use of Miracle Mineral Solution (Sodium Chlorite)
Download Citation | On Mar 1, 2011, J. A. Brown published Toxicity from the Use of Miracle Mineral Solution (Sodium Chlorite) | Find, read and cite all the research you need on ResearchGate
Embryo toxicity of sodium chlorite on three generation rats | Request PDF
Request PDF | Embryo toxicity of sodium chlorite on three generation rats | The embryo toxicity of chlorite on Wistar rat was investigated through a three-generation test. No teratogenic effect, abnormal viscera and... | Find, read and cite all the research you need on ResearchGate
The first building block is carboxyl benzoate which is found naturally in cranberries. Carboxyl benzoate is widely used as a preservative in many foods and drinks and generally recognized as a safe compound. Two arms are made out of cysteamine (found naturally in meat and on the terminal end of Co-enzyme A) which is also a widely used natural antioxidant. The cysteamines have a sulfhydryl (-SH) at their terminal ends, and the amino ends are attached on the 1st and 3rd carbon groups of the carboxyl benzoate. This allows the -SH groups to flex, rotate and take many different positions to accommodate the binding parameters of several toxic metals that are attracted to -SH groups, which covers most toxic heavy metals.
Chlorine Dioxide Is a Size-Selective Antimicrobial Agent ~(Hungary)
"ClO2, the so-called “ideal biocide”, could also be applied as an antiseptic if it was understood why the solution killing microbes rapidly does not cause any harm to humans or to animals." "The killing time for a bacterium is on the order of milliseconds in a 300 ppm ClO2 solution. Thus, a few minutes of contact time (limited by the volatility of ClO2) is quite enough to kill all bacteria, but short enough to keep ClO2 penetration into the living tissues of a greater organism safely below 0.1 mm. Bacteria are not able to develop resistance against ClO2 as it reacts with biological thiols which play a vital role in all living organisms. Conclusion: Selectivity of ClO2 between humans and bacteria is based not on their different biochemistry, but on their different size."
Human Health Effects: CHLORINE DIOXIDE, CASRN: 10049-04-4
***********Wide variety of toxicity results from studies.***DECOMP (GAS) TO CHLORIC ACID, CHLORINE, & OXYGEN IN HOT WATER *"Two adults ingested 250 ml of chlorine dioxide in water containing concn of 40 mg/l. Within 5 min of ingestion, sudden headache, nausea, abdominal discomfort, and light-headedness were observed ... effects disappeared within 5 min. ".."Industrially men exposed to low concentrations of the gas in air have been noted occasionally to suffer from irritation of the eyes and to see haloes about lights, but these effects have been minor compared to respiratory irritation. "".."CHLORINE DIOXIDE (1, 10, 100 PPM) GIVEN DAILY IN DRINKING WATER DECR BLOOD GLUTATHIONE, DECR OSMOTIC FRAGILITY, & CHANGED MORPHOLOGY OF ERYTHROCYTES IN BOTH CHICKENS & RATS AFTER TWO MO."..."CHLORINE DIOXIDE IS RAPID DISINFECTING AGENT & HAS SAME SURVIVAL RATIO AS CHLORINE BUT WITH MUCH LOWER RESIDUAL CONCN WHEN CHLORINE EXISTS AS CHLORAMINES. CHLORINE DIOXIDE IS MORE EFFECTIVE VIRUCIDE THAN CHLORINE IN SECONDARY EFFLUENT. "
Effects of dietary chlorine dioxide on growth performance, intestinal and excreta microbiology, and odorous gas emissions from broiler excreta
inc info on piglets, too -Chlorine dioxide (ClO2) is a powerful biocide that has long been used commercially to control microbial activity in various sectors. This study was co…
