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The digestive system is a potential route of 2019-nCov infection: a bioinformatics analysis based on single-cell transcriptomes
The digestive system is a potential route of 2019-nCov infection: a bioinformatics analysis based on single-cell transcriptomes
Since December 2019, a newly identified coronavirus (2019 novel coronavirus, 2019-nCov) is causing outbreak of pneumonia in one of largest cities, Wuhan, in Hubei province of China and has draw significant public health attention. The same as severe acute respiratory syndrome coronavirus (SARS-CoV), 2019-nCov enters into host cells via cell receptor angiotensin converting enzyme II (ACE2). In order to dissect the ACE2-expressing cell composition and proportion and explore a potential route of the 2019-nCov infection in digestive system infection, 4 datasets with single-cell transcriptomes of lung, esophagus, gastric, ileum and colon were analyzed. The data showed that ACE2 was not only highly expressed in the lung AT2 cells, esophagus upper and stratified epithelial cells but also in absorptive enterocytes from ileum and colon. These results indicated along with respiratory systems, digestive system is a potential routes for 2019-nCov infection. In conclusion, this study has provided the bioinformatics evidence of the potential route for infection of 2019-nCov in digestive system along with respiratory tract and may have significant impact for our healthy policy setting regards to prevention of 2019-nCoV infection.
·www.biorxiv.org·
The digestive system is a potential route of 2019-nCov infection: a bioinformatics analysis based on single-cell transcriptomes
MMS -List of other CD prod
MMS -List of other CD prod
Master Mineral Solution (MMS) Activated Sodium Chlorite = Chlorine Dioxide (CD)    The most difficult part of learning how to use MMS is its terminology. Please familiarize yourself with the follow…
·thespiritofhealth.org·
MMS -List of other CD prod
Chlorine Dioxide and Hemodialysis
Chlorine Dioxide and Hemodialysis
"ClO2 and its disinfection by-products, chlorite and chlorate. Deleterious effects of moderately high levels of these oxychlorines have been demonstrated experimentally on red blood cells, thyroid function, and development in laboratory animals. Adverse effects in controlled prospective studies in humans and in actual use situations in community water supplies have as yet failed to reveal clear evidence of adverse health effects. Among groups who may be at special risk from this suggested alternative are patients who must undergo chronic extracorporeal hemodialysis... Again, very limited human experience has failed to reveal adverse health effects... dialysis patients in carefully controlled facilities may be at no greater risk than the general population."
·pubmed.ncbi.nlm.nih.gov·
Chlorine Dioxide and Hemodialysis
Topical Antimicrobials in Combination With Admission Screening and Barrier Precautions to Control Endemic Methicillin-Resistant Staphylococcus Aureus in an Intensive Care Unit
Topical Antimicrobials in Combination With Admission Screening and Barrier Precautions to Control Endemic Methicillin-Resistant Staphylococcus Aureus in an Intensive Care Unit
We aimed to establish whether screening for methicillin-resistant Staphylococcus aureus (MRSA) and body decontamination upon admission to an Intensive Care Unit (ICU), in combination with barrier precautions, reduced rates of MRSA infection acquired on the unit. This was an interrupted time series s …
·pubmed.ncbi.nlm.nih.gov·
Topical Antimicrobials in Combination With Admission Screening and Barrier Precautions to Control Endemic Methicillin-Resistant Staphylococcus Aureus in an Intensive Care Unit
ATC Malachlorite® for treatment of patients with acute Plasmodium falciparum infection: A pilot study incorporating 500 patients in the rural area of Cameroon
ATC Malachlorite® for treatment of patients with acute Plasmodium falciparum infection: A pilot study incorporating 500 patients in the rural area of Cameroon
Malaria is one of the most widespread infectious diseases with over 2 million deaths per year in Central Africa. Since new drug combinations are characterized by the development of tolerance as well as serious side effect there is an increasing demand for a new medication. We therefore set out to study the efficacy of a sublingual tablet with a new mode of action consisting of sodium chlorite (NaClO2) plus citric acid and an artimisin extract. By adding sodium bicarbonate, an effervescent composition is attained, which when being exposed to saline, chlorine dioxide (ClO2) the active ingredi...
·gsconlinepress.com·
ATC Malachlorite® for treatment of patients with acute Plasmodium falciparum infection: A pilot study incorporating 500 patients in the rural area of Cameroon
Sodium chlorate, a herbicide and major water disinfectant byproduct, generates reactive oxygen species and induces oxidative damage in human erythrocytes | Semantic Scholar
Sodium chlorate, a herbicide and major water disinfectant byproduct, generates reactive oxygen species and induces oxidative damage in human erythrocytes | Semantic Scholar
Sodium chlorate (NaClO3) is a widely used non-selective herbicide. It is also generated as a byproduct during disinfection of drinking water by chlorine dioxide. In the present work, the effects of NaClO3 on human erythrocytes were studied under in vitro conditions. Incubation of erythrocytes with different concentrations of NaClO3 at 37 °C for 90 min resulted in significant hemolysis. Cell lysates were prepared from NaClO3-treated and untreated (control) erythrocytes and assayed for various biochemical parameters. Methemoglobin levels were significantly increased and methemoglobin reductase activity was reduced upon NaClO3 treatment. There was a significant increase in protein oxidation and lipid peroxidation with a decrease in reduced glutathione and total sulfhydryl content. This suggests the induction of oxidative stress in erythrocytes upon exposure to NaClO3. The occurrence of oxidative stress was confirmed by significantly increased generation of reactive oxygen species and lowered antioxidant response of the cells. NaClO3 treatment also increased nitric oxide levels showing induction of nitrosative stress. The activities of major antioxidant and membrane-bound and metabolic enzymes were significantly altered upon incubation of erythrocytes with NaClO3. The erythrocytes became more osmotically fragile while electron microscopic images showed gross morphological alterations in NaClO3-treated cells. These results show that NaClO3 induces oxidative stress in human erythrocytes, which results in extensive membrane damage and lowers the antioxidant response.
·www.semanticscholar.org·
Sodium chlorate, a herbicide and major water disinfectant byproduct, generates reactive oxygen species and induces oxidative damage in human erythrocytes | Semantic Scholar
Potential health effects of chlorine dioxide as a disinfectant in potable water supplies. | Semantic Scholar
Potential health effects of chlorine dioxide as a disinfectant in potable water supplies. | Semantic Scholar
Chlorination of potable water supplies high in organics may yield carcinogenic compounds such as trihalomethanes. Chlorine dioxide has been proposed as an alternative disinfectant to chlorine. However, chlorine dioxide is a strong oxidant that forms significant amounts of chlorite when added to potable water supplies, and chlorite is similar to nitrite in its molecular structure and may be similar in its mechanism of methemoglobin production. Nitrites and chlorites are thought to act synergistically to produce MetHb. Neonates and persons with G-*-PD deficiency are likely to be unusually susceptible to MetHb formation from these compounds because their red cells lack the metabolic machinery to adequately protect against oxidant stress. Since male blacks represent the largest population in the U.S. to be G-6PD deficient, Black male neonates may represent the group at highest risk to the use of chlorine dioxide as a disinfectant in the nations water supplies.
·www.semanticscholar.org·
Potential health effects of chlorine dioxide as a disinfectant in potable water supplies. | Semantic Scholar
FDA Warns Consumers Against Drinking High-Strength Hydrogen Peroxide For Medicinal Use
FDA Warns Consumers Against Drinking High-Strength Hydrogen Peroxide For Medicinal Use
The U.S. Food and Drug Administration (FDA) is warning consumers not to purchase or to use high-strength hydrogen peroxide products, including a product marketed as "35 Percent Food Grade Hydrogen Peroxide," for medicinal purposes because they can cause serious harm or death when ingested. FDA recommends that consumers who are currently using high-strength hydrogen peroxide stop immediately and consult their health care provider.
·www.sciencedaily.com·
FDA Warns Consumers Against Drinking High-Strength Hydrogen Peroxide For Medicinal Use
Case Report: Kikuchi-Fujimoto disease presenting after consumption of ‘Miracle Mineral Solution’ (sodium chlorite)
Case Report: Kikuchi-Fujimoto disease presenting after consumption of ‘Miracle Mineral Solution’ (sodium chlorite)
41-year-old woman of Malay ethnicity who presented with an 11-day history of fever and left-sided lymphadenopathy after consuming ‘Miracle Mineral Solution’ (sodium chlorite solution) for the first time. A ...
·www.ncbi.nlm.nih.gov·
Case Report: Kikuchi-Fujimoto disease presenting after consumption of ‘Miracle Mineral Solution’ (sodium chlorite)
CD effects on humans -Chlorine Dioxide Water Disinfection: A Prospective Epidemiology Study
CD effects on humans -Chlorine Dioxide Water Disinfection: A Prospective Epidemiology Study
"An epidemiologic study of 198 persons exposed for 3 months to drinking water disinfected with chlorine dioxide was conducted in a rural village. A control population of 118 nonexposed persons was also studied. Pre-exposure hematologic and serum chemical parameters were compared with test results after 115 days of exposure. Statistical analysis (ANOVA) of the data failed to identify any significant exposure-related effects. "
·pubmed.ncbi.nlm.nih.gov·
CD effects on humans -Chlorine Dioxide Water Disinfection: A Prospective Epidemiology Study
BREAKING: Researchers claim 100 percent cure rate vs. covid-19 in 100+ patient trial conducted in Ecuador, using intravenous chlorine dioxide
BREAKING: Researchers claim 100 percent cure rate vs. covid-19 in 100+ patient trial conducted in Ecuador, using intravenous chlorine dioxide
Preliminary data from a clinical trial involving more than 100 covid-19 patients in Ecuador has resulted in a claimed 100 cure rate within four days, according to Andreas Kalcker who is closely following the results of the effort. The tests were carried out by the Asociacion Ecuatoriana de Medicos Expertos en Medicina Integrativa, a group […]
·www.newstarget.com·
BREAKING: Researchers claim 100 percent cure rate vs. covid-19 in 100+ patient trial conducted in Ecuador, using intravenous chlorine dioxide
False claim that has Chlorine risk -El MMS, el dióxido de cloro o el clorito de sodio pueden ser dañinos para la salud y no hay pruebas de que curen el nuevo coronavirus
False claim that has Chlorine risk -El MMS, el dióxido de cloro o el clorito de sodio pueden ser dañinos para la salud y no hay pruebas de que curen el nuevo coronavirus
Varias publicaciones y videos compartidos en redes sociales aseguran que el nuevo coronavirus puede ser curado con dióxido de cloro, una sustancia que resulta de mezclar clorito de sodio, agua y ácido cítrico, y que es comercializada con el nombre de Solución Mineral Milagrosa (MMS por sus siglas en inglés). Sin embargo, no hay pruebas científicas que demuestren esto. Autoridades sanitarias de varios países y expertos consultados por AFP Factual alertan que su consumo con fines médicos puede ser perjudicial para la salud.
·translate.googleusercontent.com·
False claim that has Chlorine risk -El MMS, el dióxido de cloro o el clorito de sodio pueden ser dañinos para la salud y no hay pruebas de que curen el nuevo coronavirus