Treatments included injection and topical treatments) "sharp surgical debridement was performed to remove the grossly necrotic tissue, if present. A wet dressing was applied once a day using 0.9 % saline-soaked gauze. Thereby, Oxoferin was used, which represents a 5-fold diluted WF10 solution used for topical wound treatment"

"Neuraltus won't release data from the Phase II trial of NP-001 until later this year, possibly next month. The drug last summer won Food and Drug Administration fast-track and orphan drug designations, which potentially could accelerate the clinical trial process by waiving FDA fees and providing tax breaks for the company's clinical trial costs."

******!!!!**** "NP001 has been reported to reorient toxic inflammatory macrophages that invade the central nervous system into normal, protective ones"

****!!!!****!!!**** {301 pages} "Given the small percentage of viable spores that remained in the low humidity studies, increasing either the concentration of ClO2 or the exposure time could result in successful sterilization under these conditions" "Unlike ethylene oxide, sterilization with ClO2 can be achieved at ambient temperature and pressure. When at the same relative humidity and temperature (30°C), ClO2 is 1075 times more efficient" **** "results from the cytotoxicity experiments suggest that post-sterilization processing for materials sterilized with ClO2 is warranted. [to minimize residuals, etc]" "bacterial adhesion is the first step towards the development of infection" "[pg 245] possibilities explaining the difference in bacterial adhesion... including differences in the physicochemical properties of the material and the more rapid development of an accumulating substratum of bacteria (nonviable) on the surface" "the presence of proteins adsorbed to the material did not affect the bactericidal activity of the ClO2 produced by the material" "suggests... the influence of fibronectin, not necessarily on promoting bacterial adhesion, but maintaining it" "the presence of proteins adsorbed to the material did not affect the bactericidal activity of the ClO2" "presence of albumin and fibronectin did impact the viability of bacteria" "coating, such as a hydrogel (Changez et al. 2004) or a thin polymer film (Kwok et al. 1999a), could be used to control the release of ClO2 from the material, thereby extending the duration of bactericidal activity" "An alternative... would be the development of a delivery system that is activated by ultrasound" "a molecule that was affording it protection... While initial studies suggested that the molecule was extracellular, further investigation determined that it was not." "oxidization of GSH may serve as a protective mechanism for other more vital cell components" "An alternative hypothesis for the mechanism of resistance is that SP030724 is over expressing a transmembrane molecule that is either inactivating or inhibiting the bactericidal effects of ClO2." "Calculating ClO2 generator parameters"

The oral administration of chlorate salts reduces "the numbers of Gram-negative pathogens in gastrointestinal tracts of live food animals." "these data indicate that broilers rapidly convert chlorate residues to an innocuous metabolite, chloride ion, and that chlorate residues in excreta remain fairly high during the time around slaughter. Because the target tissue of chlorate is the lower gastrointestinal tract, the relatively high distribution of parent chlorate to inedible gastrointestinal tissues and low distribution to edible tissues is favorable for the biological activity and for food safety considerations."

***!!!*** "In order to prevent biofilm formation and improve sanitation prescribed was the use of stabilized liquid chlorine dioxide (ClO2) in the 4‰ concentration for so-called night "shock" treatments, and 2‰ concentration for prophylactic daily disinfection of drinking water. With the improvement of the flocks’ health status, the "shock" treatments with ClO2 were repeated in the upcoming months. As an add-on therapy, 40 mg per bird of vitamin C through drinking water for three days was prescribed. The use of non-resorptive antibiotics, AD3E vitamins and amino acid supplements was excluded because they had failed to improve the flocks’ health status in the acute phase. ...on the use of stabilized liquid ClO2 in the water supply system of the laying flocks affected by severe colisepticemia resulted in radical decrease of mortality during the next three months."

"Composition of the MMS, 2 Threats, 2.1 Described cases of intoxication by MMS 3 Legality 3.1 Court cases 4 History 4.1 Presumed curative effect"

"treating bacterial infections, including mastitis, in the udder of a mammal. The compositions include chlorine dioxide in an amount ranging from 5 ppm to 1000 ppm, and have a chlorine dioxide to chlorite ratio of at least 5:1."

****!!!!**** 2013. "there have been few reports of the effects of commonly used disinfectants (e.g. chlorine and chlorine dioxide) on human rotavirus (Human Rotavirus, HRV)" "in most previous studies, researchers have tended to ignore the important fact that different regions of the viral genome may have different resistance to disinfectants, and only PCR testing of a gene fragment of the virus, and then using the results of that part to reflect the effect of disinfectant on the entire genome of the virus, using part instead of the whole, and therefore the conclusion is unreliable. In this study, E.coli25922 and MS2 phages were used as indicative microorganisms of gut bacteria and enteroviruses in water" "The current chlorine disinfection method may be inadequate in the effective prevention and control of HRV mesohide transmission. "

{***FULL PAPER**}

"The Public Analysts Lab found the mixed MMS solution contained 90% chlorite and 10% chlorine dioxide." "level of chlorite in activated MMS was 391 milligrams per litre"

{Note: This treatment is for theoretical uses. Validations of effectiveness and safety for various uses are needed. Negative effects HAVE been experienced by some people ingesting chlorine dioxide or injecting intravenously} "pharmaceutical composition for systemic, particularly parenteral treatment of infectious diseases, based on an aqueous, sterile and pyrogen-free solution of chlorine dioxide, which contains 5 to 1000 mg/l (ppm) dissolved chlorine dioxide (CI02) and preferably 3 to 10 g/l of an ionic tonicity regulator, optionally in combination with a non-ionic tonicity regulator. The composition additionally preferably contains a pH regulator, particularly a pH buffer system, adjusted to pH 7.3-7.5, and can furthermore contain DMSO or MSM. In the ready-to-use state, the composition is free of chlorate ions, hydrochloric acid and gaseous chlorine, or contains said components in a concentration of 1 mg/L (1 ppm) at maximum each.

{Some of the statements in article about amounts and chemistry are incorrect. Some calculations are also incorrect.} "About a year ago I wrote a post on the subject of MMS and CD. Many people have since praised that post, but others have complained that it’s rather long (it is) and contains too much opinion.…"

"In Humble's video, he says his substance is the product of three chemicals: MMS, or sodium chlorite, which Humble claims he discovered has curative properties. An ordinary household acid (even one as mild as orange juice). DMSO, a "carrier" substance which Humble says helps MMS take effect.

"Elevated methemoglobin levels reflect overly oxidized blood. Elevated urea or creatinine levels reflect kidney damage. Whenever higher than usual doses are to be administered, special attention must be applied regarding kidney damage especially if the urine is acidic" "Acid renders the oxides of chlorine more reactive. Alkalinity stabilizes oxides of chlorine"

Group led by Robert Baldwin and part-funded by Sam Little claims drinking toxic fluid will eradicate HIV/Aids and other diseases

{This page contains many, many incorrect statements and hazardous recommendations}

********!!!!!*** 2008 "Note: Please take note of the POSSIBLE 'Incompatibilities' when taking MMS... I learned about how anti-oxidants and certain foods, drinks, herbs and vitamins can affect the desired results when injesting MMS. Therefore, the timing of our doses may be equally important as the quantity of our doses based on the types of things we have recently injested."

"alternative assets like citric acid will contribute to a quicker nausea threshold than the hydrochloric acid."

{CAUTION: Does not include references for verifying safety or effectiveness} {Includes CDS protocol dosages for COVID-19 uses}

Tetrachlorodecaoxide Systematic (IUPAC) name Molecular oxygen tetrachlorite hydrate Identifiers CAS number 92047-76-2 ATC. "WF 10 [Immunokine™, Macrokine™] is a 1 : 10 dilution of tetrachlorodecaoxide (TCDO) formulated for intravenous injection."

Method of treating hyperglycemia induced Red Blood Cell Disease/Dysfunction (RBCD) caused by generation of early and late glycation end products. Method of treating hemolytic anemia, smoldering hemolytic anemia, sickle cell anemia, hemorrhagic diseases, hemorrhagic stroke, hemorrhagic bleeding. Method of treating RBCD to prevent progression to diabetes associated vascular complications referred to as Syndrome X, particularly to prevent progression to chronic kidney disease, coronary vascular disease, and peripheral vascular disease.

****!!!!******** "While a wide range of oral sodium chlorite regi-mens have been used, the most popular are between 0.75 and 1.5 mg/kg given over 2 – 7 days in a row, followed by a rest period of 7 – 16 days, then repeat-ing (17,25,26). Importantly, it has never been shown that oral sodium chlorite can be absorbed at levels that affect human macrophage function. In rats given radiolabeled chlorite, 34% of the initial dose can be found excreted in the urine over the next 72 h (27). However, in monkeys, chlorite is neutralized in saliva within 1 min and by gastric fl uid in vivo in 5 min (28). Keuhne, one of the world ’ s experts on WF10, states that he studied oral WF10 and found that it “ can act on these mechanisms only intravenously, not orally ” (29). Furthermore, there are data that raise concerns about the safety of oral sodium chlo-rite. According to McGrath and Keuhne, sodium chlorite is converted under acidic conditions (such as those in the stomach) to chlorine dioxide, which can be poisonous (12,29). While a small, short- duration study failed to show evidence of oral chlo-rite toxicity in humans (30), Keuhne stopped his research on oral WF10 “ after two patients collapsed and one nearly died ” while taking it (29)"

including Tetrachlorodecaoxide (TCDO) and WF10. "This study demonstrated that WF10 at a dose of 0.5 ml/kg was associated with a sustained immunological response, i.e., sustained elevation of CD8+ T cell numbers, consistent with the proposed mechanism of action. Furthermore, a single-center, phase I/II study, was conducted in 1997 to evaluate safety and the effects of WF10" "After interaction with heme proteins, the chlorite matrix of WF10 acquires oxidizing and chlorinating properties. It has been suggested that WF10 exerts potent immunomodulatory effects most likely through generating physiologic oxidative compounds namely chloramines. Chloramines have been reported to exert cell-protective and anti-inflammatory activities. [0082] Pro-oxidative substances can also have a direct effect on transcriptional activities of the NFAT species of transcription factors."

"Treating a macrophage related disease comprising administering to a subject in need thereof an effective amount of an oxidative agent or an immunosuppressive agent. The present invention also provides a method of modulating macrophage accumulation or activation comprising administering to a subject in need thereof an effective amount of an oxidative agent or an immunosuppressive agent. The oxidative agent can be chlorite or a chlorite containing..."

"The invention features methods of treating a macrophage-associated neurodegenerative disease such as amyotrophic lateral sclerosis (ALS), Alzheimer's disease (AD), or multiple sclerosis (MS) in a subject by administering chlorite in an amount effective to decrease blood immune cell activation." "WF10, which comprises chlorite (e.g., in the form of tetrachlorodecaoxygen (TCDO)) as its active ingredient"

Discussion of Andreas Kalcker's work.

IV amt is given w/non-acidic, 99.999% pure chlorine dioxide. "CDS (for drinking) is reaction of sodium chlorite and 4% hydrochloric acid." "LD50 is 292 mg/kg for 14 days. We use 10 mg or mL in a liter of water. The difference is overwhelming."