"Cytotoxic T-cells (CTLs) play an important role in many immune-mediated inflammatory diseases. Targeting cytotoxicity of CTLs would allow to interfere with immune-mediated tissue destruction. Here we demonstrate that WF-10, a pro-oxidative compound, inhibits CTL-mediated cytotoxicity. "WF-10 - either alone or in combination with conventional immunosuppressive drugs - may be efficient to control progression of diseases, in which CTLs are crucially involved. ""

***!!!!*** {IV injections} "chlorine dioxide is less than 35 DEG C and can not decomposes. Chlorine dioxide is soluble in water, and dissolubility is 5 times of chlorine, divides pressure at room temperature 30mm/Hg, and dissolubility is 2.9g/L; At room temperature 760mm/Hg pressure (normal pressure), dissolubility is 3.1g/L. Chlorine dioxide is not easily hydrolyzed, and exists, at low concentrations (below 10mg/L) in water with monomolecular formation" "In theory, chlorine dioxide should be the anhydride of chlorous acid and chloric acid, i.e. 2ClO 2+ H 2o=HClO 2+ HClO 3 but, under actual water treatment condition, when pH value is 6 ~ 8, chlorine dioxide but has larger stability in water, and its concentration Absorbable organic halogens is at more than 48h" "[at least when generated and stored using some specific methods,] 1980ppm can be made, preserve under lucifuge sealing room temperature 25 DEG C of normal pressures, it is 1760ppm that 15 days ClO 2 solutions measure concentration, the concentration measuring chlorine dioxide for 3 months is 1285ppm" "chlorine dioxide belongs to monomolecular substance, can infiltrate the cell interior [destroy?] the virus and work.The cell of human normal, its cell membrane has the character of semipermeable membrane, chlorine dioxide can not infiltrate... The factor that need consider, chlorine dioxide degraded main component is ClO if having noxious substance to generate 2 -, [it needs to be confirmed to be?] harmless. If only considering to produce virus suppresses, in blood, chlorine dioxide concentration has 0.25ppm." *******"As the medicine of injection purposes, the adverse side effect that also will consider medicine to the body fluid balance of human body, blood pH, plasma carbon dioxide combining power, toxic and side effects, nerve centre to factors such as the sensitivitys of chlorine dioxide, carbon dioxide, whether medication suitable, can work, may occur."

{Extensive list of MMS links}

****!!!!****!!!!*** "Chlorine dioxide...is an oxidizer, less powerful than oxygen, but with greater quantity available for oxidizing. Chlorine dioxide explodes when it obtains certain chemical conditions, and is neutral with other chemical conditions. It is selective. What do we mean when we say it explodes? Well, an explosion is merely a fast Chemicals reaction, mainly oxidation that also releases energy." "...two oxygen ions... not get released so that the body can use them... They have a minus two charge. They have already done their oxidizing before they arrived in this position. They cannot oxidize further. But the chlorine combined with oxygen can. When chlorine dioxide touches a pathogen or a poison that is acidic in nature, it instantly accepts five electrons. It destroys anything that it can draw electrons from and generates heat at the same time..." "When oxygen is not capable of oxidizing it simply cannot do the job in the body that is recurred for oxygen. What sodium chlorite really does for us is it gives us chlorine dioxide, a Chemicals that is selectively to destroy almost all bad things that might exist in the body. Each tiny chlorine dioxide molecule has tremendous power to destroy those things from which it can draw electrons, but it does not have the power to draw electrons from healthy cells or aerobic bacteria." "It begins to lose some of its energy so that it no longer is explosive (unable to oxidize) it can then combine with other substances." "There is some evidence that it helps make myeloperoxidase, a chemical that the body uses to make hypochlorous acid that is then used by the immune system to further kill pathogens, killer cells and other things."

****!!!!****!!!!**** "deteriorating eyesight that may occur when using high doses of MMS for more than a few days." "Antioxidant deficiency is common with chronic diseases and advancing age. High intake or prolonged use of MMS will make this situation worse. Therefore it is important to increase antioxidant intake when using MMS. However, oxidants and antioxidants should be separated during the day or they may neutralize each other." "Because chlorine dioxide reacts especially well with vitamin C, it is advisable to take 1 gram or more when on a high dose of MMS for more than a few days to protect oxidation-sensitive structures, such as heart, brain and eyes." ******"technical sodium chlorite flakes containing 20% sodium chloride, while the MMS from StrideintoHealth (www.strideintohealth.com) is a pure sodium chlorite solution as used in the food industry. Nominally MMS is a 28% solution of the flakes but because of its high sodium chloride content the effective concentration of sodium chlorite is ****!!!!*** 22.4% which is the same in both products."

"80% is the highest concentration available for sodium chlorite due to the way it is manufactured. All sodium chlorite starts off as flakes but is usually ground up to make handling and measuring easier. A 28% (weight/weight) solution will produce 23% sodium chlorite concentration."

{CAUTION: Document includes mixing instructions and dosing, but not scientific bases for recommendations. Does not include any scientific references to verify safety and effectiveness.}

{**Contains at least one innacurate dilution. Correct proportions to make 30 oz of 100 ppm should be 3 oz of 500 ppm + 27 oz of water.} Email or leave a voice message at 949-544-1375 Ken Adachi "When Jim Humble originally talked about MMS in his books, videos and articles from 2005 forward, he said his Sodium Chlorite solution was "28%." However, it was later realized that the sodium chlorite flakes he was using to make the solutions from were a mixture of 80% sodium chlorite, plus 20% of other inert salts including sodium chloride... This mixture ratio is intentionally maintained by the manufacturer of sodium chlorite flakes in order to keep the flakes as stable as possible for shipping safety and for longer shelf life. So the correct concentration description of Jim Humble's sodium chlorite solutions should be "22.4%" "I recently discovered a more accurate way to measure the ppm percentage concentration of my Sodium Chlorite Solution by weighing a given volume of the Sodium Chlorite Solution with a sensitive digital scale. And to my surprise, I discovered that my previous extrapolated percentage quotes, presented in earlier updates to this article, were stated far too high"

2020 Aug – "The Pan American Health Organization (PAHO) has issued a warning against the use of ** "chlorine" ** products as treatments for COVID-19." “PAHO does not recommend oral or parenteral use of chlorine dioxide or sodium chlorite-based products for patients with suspected or diagnosed COVID-19 or for anyone else. There is no evidence of their effectiveness and the ingestion or inhalation of such products could cause serious adverse effects,” the document said.

The invention relates to a pharmaceutical composition for the parenteral treatment of infectious diseases, based on an aqueous, sterile and pyrogen-free solution of chlorine dioxide, the 5 to 1000 mg / l (ppm) of dissolved chlorine dioxide (CIO2) and 3 to 10 g / l of a ionic tonicity regulator, optionally in combination with a non-ionic tonicity regulator. The composition preferably also contains a pH regulator, in particular a pH buffer system adjusted to pH 7.3-7.5, and may further *****contain DMSO or MSM. The composition is free from chlorate ions, hydrochloric acid and gaseous chlorine in t... "Above all, the advantage of a high-purity CDL is that the possibility of any undesirable effects, which are described for Na-chlorite and above all for Na-chlorate in the specialist literature, is reduced even further, which is especially true for formulations and compositions is of particular importance, which should be used as infusion solutions or injection solutions. A composition according to the invention which, in addition to external, topical application, should be suitable above all for systemic, parenteral applications in the form of injection or infusion solutions,"

****!!!!****!!!! {Includes IV safety dose info} "Bacillus subtilis var. niger ATCC 9372 biological indicators (BI) (10(6) spores/BI) planted in the artificial organs were reproducibly sterilized...with a 30-min dwell time with a chlorine dioxide gas concentration of approximately 30 mg/L in 80 to 85% relative humidity at 30 degrees C. The D value (time required for 90% spore inactivation under specific conditions) was estimated to be 4.4 min." "The intravenous median lethal dose (LD50) of chlorine dioxide derivatives, chlorite and chlorate, in rats was found to be 112.8 and 2,228.6 mg/kg, respectively. In an immediate hypersensitivity test, chlorine dioxide gas-treated ovalbumin and bovine serum albumin, unlike ethylene oxide gas-treated proteins, did not cause sterilant-specific IgE-mediated hypersensitivity reactions in rats." "Results of an Ames mutagenicity test on chlorine dioxide and on the extracts of the chlorine dioxide gas-exposed oxygenators were negative."

****Wikipedia errors in statements and citations about Sodium Chlorite (& Chlorine Dioxide?)

"Composition is formed by adding a chlorine dioxide liberating compound with a weak organic acid and a heat activated saccharide." "The reaction of heat-sterilized CPD or ACD and sodium chlorite maximally liberates chlorine dioxide and minimizes the toxic effect of sodium chlorite on blood cells or blood components. The resulting solution can effectively inactivate viruses, ... can eliminate small inocula of bacteria, yeast or fungi from growing in a blood fraction, such as platelets during storage." "No adverse effects were noted when Factor VIII and Factor IX activities were measured, nor were any changes noted in hemoglobin or red blood cell survival. Accordingly, in vitro treatment according to the inventive process of baboon whole blood resulted in no detectable toxic effects." "Moreover, ****while sodium chlorite is known to have an adverse effect on blood cell integrity and functionality, blood factors or platelet viability are not significantly affected by treatment with sodium chlorite using [these specific patented] inventive compositions and processes.**** It is believed this is because the chlorite is converted by the inventive composition and process to chlorine dioxide, which is better tolerated by the cells."