Chlorine Dioxide for the Prevention of Biomaterial-Associated Infections
****!!!!****!!!**** {301 pages} "Given the small percentage of viable spores that remained in the low humidity studies, increasing either the concentration of ClO2 or the exposure time could result in successful sterilization under these conditions" "Unlike ethylene oxide, sterilization with ClO2 can be achieved at ambient temperature and pressure. When at the same relative humidity and temperature (30°C), ClO2 is 1075 times more efficient" **** "results from the cytotoxicity experiments suggest that post-sterilization processing for materials sterilized with ClO2 is warranted. [to minimize residuals, etc]" "bacterial adhesion is the first step towards the development of infection" "[pg 245] possibilities explaining the difference in bacterial adhesion... including differences in the physicochemical properties of the material and the more rapid development of an accumulating substratum of bacteria (nonviable) on the surface" "the presence of proteins adsorbed to the material did not affect the bactericidal activity of the ClO2 produced by the material" "suggests... the influence of fibronectin, not necessarily on promoting bacterial adhesion, but maintaining it" "the presence of proteins adsorbed to the material did not affect the bactericidal activity of the ClO2" "presence of albumin and fibronectin did impact the viability of bacteria" "coating, such as a hydrogel (Changez et al. 2004) or a thin polymer film (Kwok et al. 1999a), could be used to control the release of ClO2 from the material, thereby extending the duration of bactericidal activity" "An alternative... would be the development of a delivery system that is activated by ultrasound" "a molecule that was affording it protection... While initial studies suggested that the molecule was extracellular, further investigation determined that it was not." "oxidization of GSH may serve as a protective mechanism for other more vital cell components" "An alternative hypothesis for the mechanism of resistance is that SP030724 is over expressing a transmembrane molecule that is either inactivating or inhibiting the bactericidal effects of ClO2." "Calculating ClO2 generator parameters"
Total Radioactive Residues and Residues of [36Cl] Chlorate in Market Size Broilers
The oral administration of chlorate salts reduces "the numbers of Gram-negative pathogens in gastrointestinal tracts of live food animals." "these data indicate that broilers rapidly convert chlorate residues to an innocuous metabolite, chloride ion, and that chlorate residues in excreta remain fairly high during the time around slaughter. Because the target tissue of chlorate is the lower gastrointestinal tract, the relatively high distribution of parent chlorate to inedible gastrointestinal tissues and low distribution to edible tissues is favorable for the biological activity and for food safety considerations."
Description: THE USE OF STABILIZED LIQUIDE CHLORINE DIOXIDE (ClO2) FOR INTERNAL WATER SUPPLY SYSTEM SANITATION OF FARM WITH LAYING FLOCK AFFECTED BY COLISEPTICEMIA
***!!!*** "In order to prevent biofilm formation and improve sanitation prescribed was the use of stabilized liquid chlorine dioxide (ClO2) in the 4‰ concentration for so-called night "shock" treatments, and 2‰ concentration for prophylactic daily disinfection of drinking water. With the improvement of the flocks’ health status, the "shock" treatments with ClO2 were repeated in the upcoming months. As an add-on therapy, 40 mg per bird of vitamin C through drinking water for three days was prescribed. The use of non-resorptive antibiotics, AD3E vitamins and amino acid supplements was excluded because they had failed to improve the flocks’ health status in the acute phase. ...on the use of stabilized liquid ClO2 in the water supply system of the laying flocks affected by severe colisepticemia resulted in radical decrease of mortality during the next three months."
COMMISSION IMPLEMENTING DECISION of 19.6.2013 relating to the designation of "Sodium chlorite" as an orphan medicinal product ~European Parliament and of the Council
"The medicinal product “Sodium chlorite” is designated as an orphan medicinal product for the indication: Treatment of amyotrophic lateral sclerosis. "
US5252343A - Method and composition for prevention and treatment of bacterial infections - Google Patents
"treating bacterial infections, including mastitis, in the udder of a mammal. The compositions include chlorine dioxide in an amount ranging from 5 ppm to 1000 ppm, and have a chlorine dioxide to chlorite ratio of at least 5:1."
Study on the disinfection law and genomic damage effect of chlorine and chlorine dioxide on human rotavirus
****!!!!**** 2013. "there have been few reports of the effects of commonly used disinfectants (e.g. chlorine and chlorine dioxide) on human rotavirus (Human Rotavirus, HRV)" "in most previous studies, researchers have tended to ignore the important fact that different regions of the viral genome may have different resistance to disinfectants, and only PCR testing of a gene fragment of the virus, and then using the results of that part to reflect the effect of disinfectant on the entire genome of the virus, using part instead of the whole, and therefore the conclusion is unreliable. In this study, E.coli25922 and MS2 phages were used as indicative microorganisms of gut bacteria and enteroviruses in water" "The current chlorine disinfection method may be inadequate in the effective prevention and control of HRV mesohide transmission. "
Pure chlorine dioxide solution is for the method treating helicobacter pylori infections [which can cause ulcers] - Google Patents
{Note: Some statements in this document contain errors. Some dose amounts are also hazardous.} "The chlorine dioxide dissolving in water, the photodissociation quantum rate at 436nm is 0.20mol/E, rises to 1.0mol/E at 405nm"
WO2001012205A2 - Chemically-stabilized chlorite solutions for treating cancer - Google Patents
"Methods of using a stabilized chlorite matrix to modulate immune responses and treat cancer are disclosed. The stabilized chlorite matrix, when administered to a mammal in need thereof, can activate immune cells in a manner similar to interferon gamma but does not effect the production of inflammatory and shock related cytokines like tumor necrosis alpha. The stabilized chlorite matrix also upregulates the expression of the DCC protein in macrophages, a protein whose expression is related to neoplastic transformation. By activating macrophages, the stabilized chlorite matrix therefore is useful as an immunomodulatory agent and in treating cancer."
The Chlorine Dioxide Controversy - The Weston A. Price Foundation
****!!!!****!!!!*** "An important thing to keep in mind is that it is necessary to administer small doses at frequent intervals throughout the day. In this way, the dose is never high enough to cause oxidative damage because antioxidant defenses can keep up with production of reactive molecules. CD’s ability to treat malaria suggests that it might also be of benefit in treating Covid-19. It is intriguing that hydroxychloroquine, another chlorine-containing molecule that is commonly used to treat malaria, has shown promise in treating Covid-19."
Growth, ruminal measurements, and health characteristics of Holstein bull calves fed an Aspergillus oryzae fermentation extract - ScienceDirect
"Drinking water was treated with 1 mg/L of OxyMer (Oxxion, Eden Prairie, MN), which is a chlorine dioxide solution. It was used here for water sanitation in the same way that municipal water is treated. Furthermore, in efforts to minimize risk of developing and spreading bacterial pneumonia, OxyMer (25 ppm) was also included in the initial feeding of oral electrolytes given to the calves upon arrival as a prophylactic."
No, no hay evidencias de que el dióxido de cloro cure la COVID-19, ni ninguna otra enfermedad y su uso puede ser peligroso - Chequeado
Circula en Facebook una nota publicada en el sitio web de radio Facundo Quiroga, de Resistencia, Chaco, en donde se replica una entrevista realizada a Isidro Fuentes, quien dice ser biólogo molecular. En la misma, Fuentes asegura que la ingesta de dióxido de cloro puede “curar” el cáncer, la COVID-19 y hasta podría generar que […]
Florida Family Indicted for Selling Toxic Bleach as Fake “Miracle”
Miami, Florida -- A federal grand jury in Miami has returned an indictment charging a Florida man -- Mark Grenon, 62 -- and his three sons -- Jonathan Grenon, 34, Jordan Grenon, 26, and Joseph Grenon, 32 -- with fraudulently marketing and selling “Miracle Mineral Solution,” a toxic industrial bleach, as a cure for COVID-19, cancer, Alzheimer’s, diabetes, autism, malaria, hepatitis, Parkinson’s, herpes, HIV/AIDS, and other serious medical conditions, and with defying federal court orders.
Bolivia's biggest political party promised to legalize a toxic bleach to treat COVID-19. After winning a landslide victory, there is nothing to stop it
The triumph of Bolivia's MAS party was hailed by socialists worldwide, but it also marked a triumph for advocates of a toxic bleach miracle cure.
Evaluation of the antiviral effect of chlorine dioxide (ClO2) using a vertebrate model inoculated with avian coronavirus
****!!!!*** "The ClO2 treatment had a marked impact on IBV infection. Namely, viral titres were 2.4-fold lower and mortality was reduced by half in infected embryos that were treated with ClO2. Infection led to developmental abnormalities regardless of treatment. Lesions typical of IBV infections were observed in all inoculated embryos, but severity tended to be significantly lower in ClO2-treated embryos. We found no gross or microscopic evidence of toxicity caused by ClO2 at the doses used herein." "Our study shows that ClO2 could be a safe and viable way of treating and mitigating the effects of avian coronavirus infections, and raises the possibility that similar effects could be observed in other organisms."
Fringe health group Comusav promotes chlorine dioxide as a cure for Covid-19
Background From the start of the pandemic, the self-described alternative health group Coalición Mundial Salud y Vida (Comusav) has shared content with anti-vaccine sentiment online, particularly in its promotion of chlorine dioxide, also referred to as Miracle Mineral Solution (MMS). Chlorine dioxide has been declared toxic; the FDA first warned about the dangers of ingesting […]