Chemical & Biological Dynamics

Your description

bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution

Listing of current Animal Food GRAS notices including notifier, substance, intended use, intended species, and FDA’s response.

EPA search for list of disinfectants

How do I find out if a drug is approved? Is there a Web site I can go to?

National Drug Code Directory Overview

Web page listings EPA's registered antimicrobial products effective against certain blood borne/body fluid pathogens and products classified as sterilizers. Includes list of official EPA Lists.

List that can be searched

National Sanitation Foundation International (NSF) database of registered products. NSF independently tests, audits, certifies, trains and consults for the food, water, health science, sustainability and consumer product sectors.

"Both CI02 and CI02- are readily decomposed by sunlight and fluorescent lights. This can lead to significant losses during water treatment. The characteristics of the water play an important role in the nature of products resulting from light-initiated reactions. Significant levels of CIO)-, BrOf, and bromo-form can be produced. The bromide ion was found to play a particularly important role in THM formation and initiating light reactions that accellerated the decomposition of ClO2 in the dark."

****!!!!**** "ClO2 reacts quickly with the amino acids,Cysteine and Methionine (two Sulphur-containing amino acids), with Tyrosine and Tryptophan (two aromatic amino acids) and with two inorganic ions: Iron (Fe2+) and Manganese (Mn2+).A study into the antiviral effect of chlorine dioxide against Influenza Virus revealed that ClO2performed an oxidative modification of Tyrosine residue and Tryptophan residues in the viral capsid surface proteins, hemagglutinin (HA) and neuraminidase. It also reacts with free fatty acids found within the virus.Additional research on chlorine dioxide’s efficacy towards Poliovirus shows that treatment results in reduced incorporation of Uridine (one of the four base units which comprise RNA). This results in the viral genome being unable to act as template for RNA synthesis therefore resulting in the virus being unable to replicate. Chlorine dioxide is also able to disrupt Sulphurbonding interactions within the viral capsid protein which leads to changes in the virus shape resulting in a loss of pathogenic functionality. In conclusion, the mechanism of Tristel’sproprietary chlorine dioxide chemistryin destroying Coronaviridaeis expected to beacombination of oxidative modification of amino acids and fatty acids, RNA synthesis disruption and viral capsid modification. All of these in combination lead to the lysing (destruction) of the virus."

"Chlorine dioxide foam activating agents (acid solutions combined with surfactants, scale sequestrants, lubricants, detergent salts, and/or corrosion inhibitors)" **********"Sodium Chlorite is related to available chlorine dioxide by the ratio of molecular weights (67.45/90.45). For example: 87.8 ppm NaClO2 = 87.8x (67.45/90.45) ppm ClO2

{References to efficacy studies}

******** "In water, chlorine dioxide is converted to chlorite and chlorate in a 70/15 ratio 4 "

Soaring revenues and profits sent the share price of bug-busting manufacturer Tristel plc almost 11 per cent (42.50p) higher to 437.50p on the UK’s AIM exchange. The company additionally believes that its infection control technology could play a role in the fight against coronavirus. Based near Newmarket, the business hoisted revenues 22 per cent to £14.6 million and profit