Severe acute respiratory syndrome (SARS) is an acute infectious disease that spreads mainly via the respiratory route. A distinct coronavirus (SARS‐CoV) has been identified as the aetiological agent of SARS. Recently, a metallopeptidase named ...

The unwavering spread of COVID-19 has taken the world by storm. Preventive measures like social distancing and mask usage have been taken all around the globe but still, as of September 2020, the number of cases continues to rise in many countries. Evidently, ...

A SARS-CoV-2 variant carrying the Spike protein amino acid change D614G has become the most prevalent form in the global pandemic. Dynamic tracking of variant frequencies revealed a recurrent pattern of G614 increase at multiple geographic levels: national, ...

Nosocomial lower respiratory tract infections are a common cause of morbidity and mortality in ICU patients receiving mechanical ventilation. Many studies have investigated the management and prevention of ventilator-associated pneumonia (VAP), but few have focused on the role of ventilator-associat …

****!!!!*** "Chlorine Dioxide caused great variability in the inactivation kinetics between viruses and was the only treatment that did not induce genome damage... ClO2 rapidly degraded the capsid proteins of all three viruses. Protein composition alone could not explain the observed degradation trends; instead, molecular dynamics simulations indicated that degradation is dictated by the solvent-accessible surface area of individual amino acids. Finally, despite the similarities of the three viruses investigated, *****their mode of inactivation by a single disinfectant varied. This explains why closely related viruses can exhibit drastically different inactivation kinetics."

2012. by Norio Ogata. Airborne influenza virus infection of mice can be prevented by gaseous chlorine dioxide (ClO2). This study demonstrated that ClO2 abolished the function of the haemagglutinin (HA) of influenza A virus (H1N1) in a concentration-, time- and temperature-dependent manner. The IC50 during a 2 min reaction with ClO2 at 25 °C was 13.7 µM, and the half-life time of HA with 100 µM ClO2 at 25 °C was 19.5 s. Peptides generated from a tryptic digest of ClO2-treated virus were analysed by mass spectrometry. An HA fragment, 150NLLWLTGK157 was identified in which the tryptophan residue (W153) was 32 mass ...

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We demonstrated that during colonization with Streptococcus pneumoniae the nasal mucosal tissues of mice support two populations of pneumococci. Transparent-phase pneumococci can be readily washed from the outer surface, while a second population composed ...

We evaluated an eye-nose goggle to determine its usefulness in reducing nosocomial RSV infection in patients and staff members on our infant ward. During a community outbreak of RSV in 1984, infection was assessed by biweekly routine viral cultures on all ward personnel and patients and also by...

While remdesivir has garnered much hope for its moderate anti-Covid-19 effects, its parent nucleoside, GS-441524, has been overlooked. Pharmacokinetic analysis of remdesivir evidences premature serum hydrolysis to GS-441524; GS-441524 is the predominant metabolite reaching the lungs. With its synthetic simplicity and in vivo efficacy in the veterinary setting, we contend that GS-441524 is superior to remdesivir for Covid-19 treatment.

{Explanation of dynamics in lungs}

The 'bradykinin hypothesis': Biologist discovers what leads to the devastating effects of COVID-19 — and the potential fix.

Mary Ann Liebert, Inc., publishers is a privately held, fully integrated media company known for establishing authoritative peer-reviewed journals in the most promising areas of biotechnology and regenerative medicine, biomedical research, clinical medicine and surgery, technology and engineering, law, integrative medicine, public health, and environmental studies.

************** by Norio Ogata

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{Note: Minks are theorized to be susceptible to coronavirus because of having ACE2.}

CDC provides credible COVID-19 health information to the U.S.

**** {Studies currently in progress}

"Mice are not susceptible to SARS-CoV-2 infection and are, therefore, not suitable as research models" "SARS-CoV-2 can persist differently according to the surface, from hours to days (SARS-CoV-2 viability varies from hours to days depending on the surface), but infection only occurs when touching mucus membranes after contact with these contaminated surfaces. SARS-CoV-2 can also persist in air droplets for an uncertain period of time that could be longer if the virus is attached to pollution particles. Wastewater and tap water could act as SARS-CoV-2 propagation tools since positive samples of SARS-CoV-2 have been found in water samples in different countries worldwide." "All SARS viruses could be inactivated within 30 min at 20 °C with more than 0.5 mg/L residual free chlorine or 2.19 mg/L residual chlorine dioxide remaining"

Table ranks microorganisms in order of susceptibility to the various levels of disinfectants. Includes some Chlorine Dioxide info

Biosafety, facility hygiene and the latest breakthroughs in the disinfection and sanitation industries.

Books, papers and statistics on impacts on and solutions for our lives and our societies – and what are some of the solutions to boost our healthcare systems, secure our businesses, maintain our jobs and education, and stabilise financial markets and economies?

The COVID-19 pandemic has led to extensive morbidity and mortality throughout the world. Clinical features that drive SARS-CoV-2 pathogenesis in human…

General COVID resources nationally and internationally.

The rapid spread of the virus that causes COVID-19 continues to spark alarm worldwide. Countries around the world are grappling with surges in confirmed cases, hospitalizations, and deaths. Calls for preventive measures such as social distancing and ...