Diseases

The world’s undiagnosed Marfan patients often go through life unaware of the hidden killer lurking in their DNA – a gene variant which may lead to sudden death at any moment via an aortic dissection. Currently, there is no therapy available to counteract this disastrous aortic event, so patient awareness of their condition is key to prevention. To learn more about Marfan syndrome and improve diagnosis, our project needs patients to enroll online in our research cohort. In this way, patients can themselves help us contribute to new therapies and averting sudden deaths.

A congenital connective tissue disorder that confers pro basketball height also permanently benches an NBA prospect’s dreams of joining the league

Dr. Ryan Goodwin, Director, Cleveland Clinic Center for Pediatric Orthopaedics and Scoliosis Surgery is joined by physical therapists Raquel Griffis, PT, DPT and Lisa Seely, PT to discuss the changes that occur to the musculoskeletal system with Marfan Syndrome, treatment options, when to seek a physical therapist (PT), how to work with a PT, and a case presentation of a child with Marfan. Filmed at the Regional Symposium on Marfan Syndrome and Related Disorders presented by Cleveland Clinic and The Marfan Foundation

High arterial tortuosity may signify early arterial pathology which may precede development of intracranial aneurysms. We measured arterial tortuosity of intracranial vessels and reviewed the medical records of three groups of patients: with intracranial ...

The tortuosity index of intracranial arteries is an easily calculated and highly reproducible measure, which shows a high specificity for Marfan syndrome and Loeys-Dietz syndrome and may be useful in differentiating these 2 entities.

There is a general assumption in the cerebrovascular literature that there is an association between carotid artery tortuosity and connective tissues disease; however, this has not been firmly established. The purpose of this study was to determine the ...

kidney cysts seems to be linked to an increased aortic dissection risk,,,

According to this study the drug Irbesartan reduces aortic dilatation in children and young adults with Marfan syndrome.

Find symptoms and other information about Marfan syndrome type 1.

Marfan Syndrome. Introduction & Overview. What is Marfan Syndrome?. Connective Tissue Disorder Malformation of Chromosome 15 Affects bodily structures: Skeleton Lungs Eyes Heart Blood vessels. What is Connective Tissue?. “Cellular Glue”

Postural orthostatic tachycardia syndrome, or POTS, is a little known and often undiagnosed disorder that can cause racing heart, dizziness and other symptoms.

Simple, specific diagnostic list

A full length video discussing all aspects of Marfan Syndrome by Dr Child MD Marfan Trust

Marfan syndrome is a condition that affects the connective tissues of the entire body, including joints, eyes, heart, blood vessels, lungs, bones & spinal cord.

Marfan Syndrome (MFS) is a systemic disorder caused by mutations in fibrillin-1. The most common cause of mortality in MFS is dissection and rupture of the aorta. Due to a highly variable and age-dependent clinical spectrum, the diagnosis of MFS still ...

Do you find it hard to keep track of your supplies? Make it easy by putting together a diabetes toolkit.

Marfan syndrome (MFS), a multisystemic connective disorder, caused by fibrillin 1 gene mutations with autosomal dominant inheritance. The disease spectrum is wide and the major causes of death are related to aortic root aneurysm or dissection. The purposes ...

Marfan syndrome is an autosomal dominant, multisystem disease characterized by long bone overgrowth and other skeletal abnormalities, dislocation of the ocular lens, pneumothorax, decreased skeletal muscle mass, mitral valve prolapse, and dilatation of the aortic root. Antoine Bernard-Jean Marfan first described the syndrome in 1896 in a young patient with peculiarly long and thin digits (subsequently termed arachnodactyly), elongated limbs (which he termed dolichostenomelia), and congenital contractures of multiple joints. Because of the latter feature, this patient may really have had congenital contractural arachnodactyly, a connective tissue disorder not described until 1968. For the half century subsequent to Marfan’s report, features in other systems were described in patients with thin, elongated limbs: mitral valve disease in 1912; dislocation of the ocular lens in 1914; ruptured aortic aneurysm in 1918; aortic root dilatation and dissection in 1943; and autosomal dominant inheritance in 1949. Manifestations occur in many other tissues and organs and are increasingly being recognized as patients survive to older ages.1

WebMD's guide to Marfan syndrome, an inherited disease that affects the heart.

Marfan syndrome is a genetic disease affecting the body's connective tissues, causing problems with the heart and blood vessels, eyes, and bones.

If you’re a man, you can prioritize and improve your health by using your TRICARE preventive care benefits. You can also take advantage of Humana Military’s support programs. Here are health resources to know.

Long before WeightWatchers became a weight loss empire, the legacy dieting company started as a small support group in the 1960s. The company rose to popularity preaching a message of moderation and making healthy choices. But in what some call a surprising pivot, WeightWatchers is changing the way the company does business. On today’s Chasing Life, CEO Sima Sistani sits down with Dr. Sanjay Gupta to share why she’s making these big changes, namely, embracing telehealth and weight loss drugs like Wegovy. Learn more about your ad choices. Visit podcastchoices.com/adchoices

View photos of wet and dry macular degeneration and videos about AMD and your eyes. These pictures of retinas - called fundus photographs - show the different effects of wet and dry macular degenerati

If you're fighting a painful toothache, check out these 29 easy, low-maintenance DIY at-home remedies to try while you wait to see the dentist.

Are you exhausted, experiencing fuzzy thinking and suffering from muscle weakness/joint pain? We cover common candida symptoms and a natural treatment plan.

The sinuvertebral nerve, also known as the recurrent meningeal nerve, or the recurrent nerve of Luschka, is a branch of the primary ventral ramus and grey ramus communicans in the intervertebral foramen. It enters the spinal canal and supplies th...