Awareness of the risk of airborne transmission of SARS-CoV-2 makes patients hesitant about using inhaled medications that are considered as a potential source of viral transmission and immunosuppression.

****!!!!**** "GSH in the epithelial lining fluid (ELF) of the lower respiratory tract is thought to be the first line of defense against oxidative stress. Inhalation (nebulized or aerosolized) is the only known method that increases GSH's levels in the ELF."

"Any molecular target of the oxidative stress induced by chlorine dioxide has been not known in insects. This study assessed an enzyme activity of acetylcholinesterase (AChE) as a molecular target of chlorine dioxide in the Indianmeal moth, Plodia interpunctella. AChE activities were varied among developmental stages of P. interpunctella. Injection of chlorine dioxide with lethality-causing doses significantly increased AChE activity of the fifth instar larvae of P. interpunctella. Exposure of the larvae to chlorine dioxide fumigant also significantly increased AChE activity. The fifth instar larvae of P. interpunctella exhibited a negative phototaxis. However, chlorine dioxide treatment significantly interrupted the innate behavior."

"Recommendations for health care providers and facilities in treating patients who require ventilation assistance due to COVID-19 complications"

A method of controlling floating virus infection. The method includes the step of: supplying chlorine dioxide gas into a space where floating virus can be present by a gas concentration which allows the animal to live or stay, but deactivates the virus.

*This method can help identify highly toxic substances so they are not used.

******!!!!***!!!!*** 2020. {Some statements may need to be verified} "at 20 degrees Celsius y = 0.0316 indicating that in equilibrium 1 cm3 aqueous phase contains (0.0316)-1 = 31.6 times more ClO2 molecules than 1 cm3 gas phase." "Thus, the following formula can be used to calculate the ClO2 concentration of the gas phase being in equilibrium with a ClO2 solution at 20 degrees C: [ClO2]gas in ppm (V/V) = 11.3 x [ClO2]aq in ppm (m/m)" 1) Global prevention approach: Disinfection of air spaces, hard surfaces, and persons simultaneously with airborne aqueous ClO2 solutions. 2) Personal disinfection techniques: Disinfection of the mouth and the upper respiratory track with gargling. [Note: In two lab tests, a chlorine dixode mouth rinse tested directly against SARS-CoV-2 was 98% effective in 30 seconds. This may hold potential in reducing contagion during ventilator-tube insertion.] 3) Disinfection of the lower respiratory track through inhalation of low-level chlorine dioxide.

***device is a nebulizer superior to imported devices that turns liquid medicine into a fine mist, with “10 times the life span” of nebulizers manufactured overseas. The new North Korean nebulizer can be filled with ingestible antibiotics that are then inhaled in mist form. State media said the generation of ultrasonic waves through the medicine produces droplets for inhalation

****!!!!***!!!!**** (2014) {Disinfection in room air; or Treatment inside body of person through inhalation. Includes **valuable** study of different ClO2 air concentrations being administered to mice in different timings after being exposed to flu virus.} "chlorine dioxide gas, even at an extremely low concentration of e.g. 0.05 to 0.1 ppm, is capable of deactivating virus or depriving its infectability" " In some of the experiments, however, the introduction of chlorine dioxide gas was effected with delays relative to the introduction of the virus-containing aerosol... to check whether the chlorine dioxide gas can prevent onset of viral disease resulting from the virus which has entered the lungs already."