Medications

Find patient medical information for Risperidone (Risperdal, Risperdal Consta) on WebMD including its uses, side effects and safety, interactions, pictures, warnings, and user ratings

Compare Risperdal and Seroquel side effects, costs and risks for treating Bipolar Disorder and Schizophrenia.

The dopaminergic partial agonism of the so-called third-generation antipsychotics (TGAs; aripiprazole, brexpiprazole, cariprazine) is hypothesized to cause impulse control disorders (ICDs). Relevant warnings by the Food and Drug Administration (FDA) ...

Constipation, a prevalent condition affecting both children and adults, poses significant challenges if left unmanaged, potentially leading to complications like fecal impaction. With constipation ranking high among outpatient gastrointestinal (GI) diagnoses clinicians must navigate a diverse array of pharmacologic options, including over-the-counter laxatives in various formulations such as bulking agents, stool softeners, stimulant laxatives like bisacodyl, and osmotic laxatives. To optimize patient outcomes and enhance their quality of life, clinicians should engage in thorough discussions with patients, coordinate closely with nurses or caregivers, and carefully weigh the risks and benefits of laxative use, particularly bisacodyl, which demands attention due to its potential adverse effects.

Tamsulosin (Flomax) may not be right for you. Learn about alternative treatments for benign prostatic hyperplasia (BPH).

The renin–angiotensin–aldosterone system plays an important role in the pathophysiology of hypertension and is closely related with cardio- and cerebrovascular events and chronic kidney diseases. Each angiotensin receptor blocker (ARB) is important ...

What is the difference between statins, and which is the most effective? Compare the intensity of lovastatin, atorvastatin, and other statins here.

Abstract. Bipolar depression remains a major unresolved challenge for psychiatric therapeutics. It is associated with significant disability and mortality

Bipolar disorder, with mood swings between depression and mania, may affect up to 1.5% of adults, and increases the risk of suicide and disability. Most people improve over time, but two thirds may have residual dysfunction, and at least 40% may ...

An important study led by BBRF grantees has closely examined a commonplace pharmacologic property of many antipsychotic and other medications commonly prescribed to people with chronic schizophrenia and has concluded that this property can "substantially" contribute to the risk of cognitive impairment.

Objective To investigate whether different anticholinergic drug treatments for overactive bladder have differential risks for incident dementia, in a large representative population of older adults in England.Design Nested case-control study.Setting General practices in England providing data to the Clinical Practice Research Datalink (CPRD) GOLD database, with linked patient admission records from secondary care (Hospital Episode Statistics), 1 January 2006 and 16 February 2022Participants 170 742 patients aged ≥55 years, with a first reported diagnosis of dementia during the study period, matched by age, sex, and general practice with 804 385 individuals without dementia (controls).Interventions Cumulative drug use (defined using total standardised daily dose) of different anticholinergic drugs used for the treatment of an overactive bladder, and a non-anticholinergic drug, mirabegron, in the period 3-16 years before a diagnosis of dementia (or equivalent date in matched controls).Main outcome measures Odds ratios for onset of dementia associated with the different anticholinergic drugs used for the treatment of an overactive bladder, adjusted for sociodemographic characteristics, clinical comorbidities, and use of other anticholinergic drug treatments.Results The study population comprised 62.6% women, and median age was 83 (interquartile range 77-87) years. 15 418 (9.0%) patients with dementia and 63 369 (7.9%) controls without dementia had used anticholinergic drugs for the treatment of an overactive bladder in the 3-16 years before diagnosis (or equivalent date for controls). The adjusted odds ratio for dementia associated with the use of any anticholinergic drug used to treat an overactive bladder was 1.18 (95% confidence interval (CI) 1.16 to 1.20), and was higher in men (1.22, 1.18 to 1.26) than women (1.16, 1.13 to 1.19). The risk of dementia was substantially increased with the use of oxybutynin hydrochloride (adjusted odds ratio 1.31, 95% CI 1.21 to 1.42 and 1.28, 1.15 to 1.43 for use of 366-1095 and 1095 total standardised daily doses, respectively), solifenacin succinate (1.18, 1.09 to 1.27 and 1.29, 1.19 to 1.39), and tolterodine tartrate (1.27, 1.19 to 1.37 and 1.25, 1.17 to 1.34). No significant increases in the risk of dementia associated with darifenacin, fesoterodine fumarate, flavoxate hydrochloride, propiverine hydrochloride, and trospium chloride were found. The association between mirabegron, a non-anticholinergic drug, and dementia was variable across the dose categories and might be caused by previous use of anticholinergic drugs for the treatment of an overactive bladder in these individuals.Conclusions Of the different anticholinergic drugs used to treat an overactive bladder, oxybutynin hydrochloride, solifenacin succinate, and tolterodine tartrate were found to be most strongly associated with the risk of dementia in older adults. This finding emphasises the need for clinicians to take into account the possible long term risks and consequences of the available treatment options for an overactive bladder in older adults, and to consider prescribing alternative treatments that might be associated with a lower risk of dementia.

Anticholinergic drugs are used to treat many conditions, including chronic obstructive pulmonary disorder (COPD) and overactive bladder (OAB). Explore our list. Learn how they work, side effects, risks, and more.

Learn about Cogentin (benztropine), a drug sometimes used in people with bipolar disorder to treat drug-induced parkinsonism that can occur with bipolar medications.

This post by J is about his withdrawal. He takes a different approach to the ones outlined in Side Effexor Withdrawal through to Helping H - an engineering approach rather than a therapy one. Next week we will feature a post about some of the TRP (Transient Receptor Potential) Channels he mentions. I usually work

Learn about the side effects of Latuda (lurasidone), from common to rare, for consumers and healthcare professionals.

[Entertaining phrasing!] Explore Depakote's behavioral side effects, from mood swings to cognitive changes. Learn strategies to manage these impacts and make informed treatment decisions.

Quick easy-to-read overview of Latuda. Includes: how it works, upsides, downsides, bottom line, tips, response and effectiveness.

Central nervous system (CNS) depressants used to manage symptoms of psychosis and anxiety disorders include antipsychotics and anxiolytics, which may cause psychosis. Antipsychotics are also…

Fenbendazole is a benzimidazole anthelmintic agent commonly used to treat animal parasitic infections. In humans, other benzimidazoles, such as mebendazole and albendazole, are used as antiparasitic agents. Since fenbendazole is not currently approved by the FDA or EMA, its pharmacokinetics and safety in humans have yet to be well-documented in medical literature. Despite this, insights can be drawn from existing in vitro and in vivo animal studies on its pharmacokinetics. Given the low cost of fenbendazole, its high safety profile, accessibility, and unique anti-proliferative activities, fenbendazole would be the preferred benzimidazole compound to treat cancer. To ensure patient safety in the repurposing use of fenbendazole, it is crucial to perform clinical trials to assess its potential anticancer effects, optimal doses, therapeutic regimen, and tolerance profiles. This review focuses on the pharmacokinetics of orally administered fenbendazole and its promising anticancer biological activities, such as inhibiting glycolysis, down-regulating glucose uptake, inducing oxidative stress, and enhancing apoptosis in published experimental studies. Additionally, we evaluated the toxicity profile of fenbendazole and discussed possibilities for improving the bioavailability of the drug, enhancing its efficacy, and reducing potential toxicity.

ARIPiprazole and losartan may have additive effects in lowering your blood pressure.

!!!! Contraindicated in renal insufficiency (serum creatinine 1.5 mg/dL in men or abnormal creatinine clearance

Cholinesterase inhibitors are drugs that prevent the breakdown of acetylcholine, and blocks the action of acetylcholinesterase in the body. Researchers believe that decreased levels of acetylcholine in the brain causes Alzheimer's disease symptoms. Common side effects of cholinesterase inhibitors are insomnia, abnormal dreams, weight loss, headache, nausea, vomiting, diarrhea, confusion, and fatigue.

Compare cholinesterase inhibitors (acetylcholinesterase inhibitors). View important safety information, ratings, user reviews, popularity and more.

~Venlafaxine and ODV have no significant affinity for muscarinic, ~Aggression may occur in some patients who have received antidepressants, including venlafaxine treatment, dose reduction, or discontinuation ~aggression have been observed in patients during changes in venlafaxine dosing regimen, including during discontinuation ~Discontinuation.. symptoms include aggression, agitation,

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