Medications

[Entertaining phrasing!] Explore Depakote's behavioral side effects, from mood swings to cognitive changes. Learn strategies to manage these impacts and make informed treatment decisions.

Quick easy-to-read overview of Latuda. Includes: how it works, upsides, downsides, bottom line, tips, response and effectiveness.

Central nervous system (CNS) depressants used to manage symptoms of psychosis and anxiety disorders include antipsychotics and anxiolytics, which may cause psychosis. Antipsychotics are also…

Fenbendazole is a benzimidazole anthelmintic agent commonly used to treat animal parasitic infections. In humans, other benzimidazoles, such as mebendazole and albendazole, are used as antiparasitic agents. Since fenbendazole is not currently approved by the FDA or EMA, its pharmacokinetics and safety in humans have yet to be well-documented in medical literature. Despite this, insights can be drawn from existing in vitro and in vivo animal studies on its pharmacokinetics. Given the low cost of fenbendazole, its high safety profile, accessibility, and unique anti-proliferative activities, fenbendazole would be the preferred benzimidazole compound to treat cancer. To ensure patient safety in the repurposing use of fenbendazole, it is crucial to perform clinical trials to assess its potential anticancer effects, optimal doses, therapeutic regimen, and tolerance profiles. This review focuses on the pharmacokinetics of orally administered fenbendazole and its promising anticancer biological activities, such as inhibiting glycolysis, down-regulating glucose uptake, inducing oxidative stress, and enhancing apoptosis in published experimental studies. Additionally, we evaluated the toxicity profile of fenbendazole and discussed possibilities for improving the bioavailability of the drug, enhancing its efficacy, and reducing potential toxicity.

ARIPiprazole and losartan may have additive effects in lowering your blood pressure.

!!!! Contraindicated in renal insufficiency (serum creatinine 1.5 mg/dL in men or abnormal creatinine clearance

Cholinesterase inhibitors are drugs that prevent the breakdown of acetylcholine, and blocks the action of acetylcholinesterase in the body. Researchers believe that decreased levels of acetylcholine in the brain causes Alzheimer's disease symptoms. Common side effects of cholinesterase inhibitors are insomnia, abnormal dreams, weight loss, headache, nausea, vomiting, diarrhea, confusion, and fatigue.

Compare cholinesterase inhibitors (acetylcholinesterase inhibitors). View important safety information, ratings, user reviews, popularity and more.

~Venlafaxine and ODV have no significant affinity for muscarinic, ~Aggression may occur in some patients who have received antidepressants, including venlafaxine treatment, dose reduction, or discontinuation ~aggression have been observed in patients during changes in venlafaxine dosing regimen, including during discontinuation ~Discontinuation.. symptoms include aggression, agitation,

Chemical

Cholinergic transmission at muscarinic acetylcholine receptors (mAChR) has been implicated in higher brain functions such as learning and memory, and loss of synapses may contribute to the symptoms of Alzheimer disease. A heterogeneous family of ...

Cognitive impairment is a core symptom of schizophrenia and a major determinant of poor long-term functional outcomes. Despite considerable efforts, we do not yet have any approved pharmacological treatments for cognitive impairment associated with ...

The muscarinic receptor agonist xanomeline has antipsychotic properties and is devoid of dopamine receptor–blocking activity but causes cholinergic adverse events. Trospium is a peripherally restri...

This randomized clinical trial evaluates the efficacy and safety of xanomeline-trospium chloride vs placebo in adults with schizophrenia.

FDA approved Cobenfy (xanomeline and trospium chloride) capsules for oral use for the treatment of schizophrenia in adults.

Dementia with Lewy bodies (DLB) is a type of dementia characterized by changes in sleep, behavior, cognition, movement, and regulation of automatic bodily functions. Memory loss is not always an early symptom. The disease worsens over time and is usually diagnosed when cognitive impairment interferes with normal daily functioning. Together with Parkinson's disease dementia, DLB is one of the two Lewy body dementias. It is a common form of dementia, but the prevalence is not known accurately and many diagnoses are missed. The disease was first described on autopsy by Kenji Kosaka in 1976, and he named the condition several years later.

Learn about the side effects of aripiprazole, from common to rare, for consumers and healthcare professionals.

Yes, antibiotics are miracle drugs, but they have some quirks. Among them are unexpected interactions with the brain. Here are five surprising connections.