Daily aspirin reduces cancer risk and slows its spread, study confirms. Taking a low dose of aspirin every day may reduce the risk of cancer and slow the spread of the disease, according to a study that followed the health of more than 100,000 patients. : r/science
platelets release pro-angiogenic proteins- proteins that promote the growth of new blood vessels
Tumors hijack these platelets to be able to grow new blood vessels to support their rapid growth
Without new blood vessels, a tumor cannot grow.
ASPIRIN's mechanism of action is to inhibit platelets
Therefore, no platelets = no new blood vessels = less tumor growth
Your body does not need to grow new blood vessels (angiogenesis) unless you have been injured.
Cancer, on the other hand, grows new blood vessels to supply the tumor as it grows.
That's why anti-angiogenics are used to fight cancer.
yes, increased vascularity inside of your muscles will make them perform better.
Cancer is closely associated with inflammation. Aspirin inhibits inflammation.
Inflammation is strongly related to poor blood circulation.
No wonder exercise and a healthy diet helps then.
A recent article on estrogen-induced apoptosis after long-term estrogen deprivation in breast cancer demonstrated that such an inflammatory pathway can actually be used to kill cancer cells, and recommended a review of NSAID use during some treatments to avoid dampening the effects of therapy.
Since aspirin permanently inhibits COX I, that receptor must be recycled and a new one made to replace it. With ibuprofen, the receptor eventually regains activity after ibuprofen wears off because it is a reversible COX inhibitor.
aspirin can cause gastrointestinal bleeding, ulcers and kidney problems over long periods of time. It really depends on the dosage
Giving aspirin or other salicylates (like those found in pepto bismol) to children under 12 can cause Reye's syndrome
Low-dose aspirin has two benefits: lowering heart attack risk and stroke risk (mostly in women), and possibly this new cancer risk reduction.
I was on full (325 mg) dose every day for a year and then on a half dose for a year and it caused my stomach lining to break down and start bleeding.
At least in women all cause mortality decreases with asprin use. The effect with heart attacks was related to more short term asprin use whereas effect on cancer was associated with longer term asprin use.
GI bleeding is the biggest risk. There is also a risk of worsening bleed from trauma (for example: you hit your head really hard! how much will you bleed inside your skull?) but this risk minimal in a younger person and in the elderly is much safer than the blood thinner warfarin
acid reflux, for this reason I don't take one
If you have an asymptomatic infection w/ H pylori, the bacteria most likely to be associated with an ulceration, prolonged use of daily aspirin can uncover that
prolonged use of higher doses of NSAIDs-non steroidal anti inflammatories, like ibuprofen-can give you kidney problems, tho usually it's in conjunction with some other cause of renal disease like hypertension or diabetes.
Still possible to have embolic stroke on warfarin but it's much more rare. Hemorrhagic stroke would be a risk, tho.
increased risk of hemorrhagic stoke, which is the single biggest side effect by mortality.
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