Acidified sodium chlorite solution: A potential prophylaxis to mitigate impact of multiple exposures to COVID-19 in frontline health-care providers
(2020). {***Click "Display Table" button for important dosing instructions***} " tolerability data-on-file (2017) shared by Sinox Pharma, Inc. show that a 0.008% (wt/vol %) ClO2 solution derived from ASC is nonirritating when administered as an intranasal cleanser to individuals with sub-clinical or clinical sinusitis." "more recent evaluations in animals and humans demonstrate that exposure to low concentrations of ASC or ClO2 (≤0.2% and 0.02%, [2000 ppm ASC and 200 ppm ClO2] respectively) such as those found to be effective in human mouth rinse studies are well tolerated" "Snoot™ (Sinox Pharma, Inc.) at the ‘Original’ strength. This formulation yields between 60 parts per million (ppm) and 75 ppm (~0.01% wt/vol) ClO2 over the course of 12 hours" "DioxiRinse™ (Frontier Pharmaceutical, Inc.) to be used at the ‘Standard Strength’ yielding a concentration of ~40 ppm (0.006% wt/vol) ClO2." "immediate cleansing using both products is suggested, even if the recommended maximum use of 4 times in a 12-hour period is exceeded. However, 6 administrations in a 24-hour period are strongly discouraged."