Topical Oropharyngeal Vancomycin to Control Methicillin-Resistant Staphylococcus Aureus Lower Airway Infection in Ventilated Patients
"In the setting of MRSA endemicity, the prevention of MRSA carriage by topical oropharyngeal vancomycin was more effective in reducing carriage and infection of the lower airways than treatment of established carriers."
Efficacy of Stabilized Chlorine Dioxide-Based Unflavored Mouthwash in Reducing Oral Malodor: An 8-week Randomized Controlled Study
The results of this study suggest the daily use of a stabilized chlorine dioxide-containing unflavored mouthwash as an adjunct to brushing with fluoride toothpaste provides a clinically relevant reduction in oral malodor after 3 weeks of twice-daily use.
Phosphate Buffer-Stabilized 0.1% Chlorine Dioxide Oral Rinse for Managing Medication-Related Osteonecrosis of the Jaw
This literature review supports the use of phosphate buffer-stabilized 0.1% chlorine dioxide mouthrinse in the management of MRONJ lesions either as a first line of therapy or after 0.12% chlorhexidine had not been effective.
Efficacy of chlorine dioxide mouthwash against halitosis
To ascertain the effectiveness of using chlorine dioxide mouthwash in addressing halitosis. Forty people were divided equally into the test group (required to gargle with mouthwash containing chlorine dioxide) and the control group (required to gargle with aquadest). The volatile sulfur compound (VSC) and organoleptic scores were measured before gargling and 30 min, 2 h, 4 h, and 6 h after. The Wilcoxon test analysis showed a significant difference (p<0.05) in the mean value of VSC scores between the test group and the control group in four testing periods after gargling. Chlorine dioxide mouthwash is effective in addressing halitosis.
PPE Disinfectant -Acidified sodium chlorite solution: A potential prophylaxis to mitigate impact of multiple exposures to COVID-19 in frontline health-care providers
(2020). Acidified sodium chlorite solution: A potential prophylaxis to mitigate impact of multiple exposures to COVID-19 in frontline health-care providers. Hospital Practice. Ahead of Print.
Comparison of chlorine dioxide and dichloroisocyanurate disinfectants for use in the Dental setting - PubMed
Chlorine dioxide and sodium dichloroisocyanurate containing disinfectants can be used in the denta settings for surfaces and heat sensitive instruments. However, chlorine dioxide is advantageous because it is non-corrosive and the effective concentration is lower than that recommended for sodium dic …
Topical preparations to reduce SARS‐CoV‐2 aerosolization in head and neck mucosal surgery
The COVID‐19 pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) has put health care workers at risk when exposed to aerosolized viral particles during upper airway mucosal surgery. The objective ...
Topical preparations to reduce SARS‐CoV‐2 aerosolization in head and neck mucosal surgery
***** "The authors believe that the topical application of PVP‐I is safe and may help to reduce the viral load, and the potential aerosolization, of SARS‐CoV‐2. Until confirmatory studies are conducted, our institutional consensus is to dilute commonly available PVP‐I (typically 7.5%) 1:3 with saline to achieve a less than 2% concentration and bulb syringe the solution into the oral/nasal cavity, after intubation, but immediately prior to head and neck procedures that require instrumentation of the upper airway mucosa during the COVID‐19 pandemic. We suggest leaving the solution in for approximately 1 minute before irrigating with saline and suctioning it out to reduce residual absorption and limit tissue staining – though the optimal concentration and application time, if any, are currently unknown."
Impact of Periodontal Therapy on General Health: Evidence from Insurance Data for Five Systemic Conditions
Treatment of periodontal (gum) disease may lessen the adverse consequences of some chronic systemic conditions.To estimate the effects of periodontal …
5 Interesting Uses of Chlorine Dioxide + Safety, Side Effects - SelfHacked
since it has a low pH, long-term exposure may harm teeth... Chlorine dioxide mouthwashes are available for purchase. If you use one, take special care not to swallow the solution, as the ***[Note: This concentration is actually safe for limited consumption, although is higher than concentration officially approved for drinking water] concentration of chlorine dioxide in these products is much higher than the threshold for safe consumption***
Periodontal tray application of chlorine dioxide gel as an adjunct to scaling and root planing in the treatment of chronic periodontitis - PubMed
The application of chlorine dioxide gel using the custom tray after SRP in the treatment of chronic periodontitis showed better clinical improvement in pocket depth reduction and bleeding index compared to SRP alone.
Bactericidal activity of stabilized chlorine dioxide as an endodontic irrigant in a polymicrobial biofilm tooth model system - PubMed
The triple-inoculation bovine tooth model system is a robust, consistent, and reproducible model system to study polymicrobial biofilms. It should be used with the knowledge expansion of biofilm structure and function as well as the development of antimicrobial protocols.
An in vitro evaluation of the antibacterial efficacy of chlorine dioxide on E. faecalis in bovine incisors - PubMed
This study investigated the ability of chlorine dioxide to eliminate Enterococcus faecalis from dentinal tubules of bovine incisors. Thirty-seven extracted bovine incisor roots were sectioned into seventy-four 5 mm disks. Standardized lumens were filled with either sterile Brain Heart Infusion Broth …
An in vitro study comparing a two-part activated chlorine dioxide oral rinse to chlorhexidine
"The difference in effectiveness between the chlorine dioxide gas of Oracare and stabilized/precursor forms of chlorine dioxide (sodium chlorite) was evident as none of the mouthrinses using the latter inactivated significantly greater levels of VSCs than the water control." "The MICs for Oracare were higher than those for chlorhexidine when compared directly against a panel of 11 microbial species. However, when normalized to parts per million of the active ingredients, the Oracare rivaled the activity of chlorhexidine and exceeded it in activity toward the periodontal pathogen Aggregatibacter actinomycetemcomitans. The Oracare rinse removed a statistically higher percentage of VSCs than chlorhexidine"
Acidified sodium chlorite solution: A potential prophylaxis to mitigate impact of multiple exposures to COVID-19 in frontline health-care providers
"Snoot™ (Sinox Pharma, Inc.) at the ‘Original’ strength. This formulation ... yields between 60 parts per million (ppm) and 75 ppm (~0.01% wt/vol) ClO2 over the course of 12 hours," "DioxiRinse™ (Frontier Pharmaceutical, Inc.) to be used at the ‘Standard Strength’ yielding a concentration of ~40 ppm (0.006% wt/vol) ClO2. If an HCP has direct exposure to a cough or sneeze of individual with presumed COVID-19, immediate cleansing using both products is suggested, even if the recommended maximum use of 4 times in a 12-hour period is exceeded. However, 6 administrations in a 24-hour period are strongly discouraged."
Evaluation of Chlorine Dioxide Irrigation Solution on the Microhardness and Surface Roughness of Root Canal Dentin - PubMed
The aim of this study was to evaluate the effect of chlorine dioxide and various other more common irrigation solutions on the microhardness and surface roughness of root canal dentin. Fifty human maxillary central incisors were sectioned longitudinally and treated for 1 minute with 5 ml of the foll …
