Mouth & Nasal Uses

*****!!!**** {Solumium} "High purity ClO2 solution is significantly more effective than CHX, NaOCl and Listerine in case of aerobic and facultative anaerobic bacteria and Candida." "Titrations showed that ***dentin powder depleted the ClO2 *** amount to 70% by the end of the first minute. This means, that minimum 40 ppm ClO2 remained of the 66 ppm. The reduction of ClO2 did not stop at any intermediate stage, but continued until chloride,till the end of the reaction" "The high purity ClO2 has no pulp tissue dissolving effect." "In vivo, high purity ClO2 solution significantly decreases the salivary S. mutans and total bacteria count even after one rinse" "ClO2does not interact with the CHX and does not increase the amount of toxic PCA found inCHX, so their simultaneous use is secure in the root canal" "There was no significant change in the number of S. mutans, L acidophilus and C. albicans" "ClO2 solution is significantly more effective than other currently used disinfectants in case of aerobic, facultative anaerobic bacteria (E. faecalis, S. mutans) and Candida."

*Shock treatments* contain high-level disinfectants that are strong enough to remove biofilm. They effectively remove (or "shock the system") bacteria and biofilm but are not safe for patient contact...Combine Continuous with Shock - always use both a shock treatment and a continous treatment if you want consistently safe waterlines. Test Quarterly - it's the only way to know if what you're doing is working. DOWNLOAD THE Dental Water Treatment SELECTION GUIDE... Continuous treatment--failure rate of all of treatment products together is still 31%.... Daily liquids category chlorine dioxide based chemistries. They are added to the independent water bottle of waterlines each time it is refilled. This one of the least popular methods... the data indicates that the ***actual effectiveness results are the lowest category tested.***

CDC provides credible COVID-19 health information to the U.S.

An antimicrobial oxychlorine oral rinse composition for preventing and treating oral malodor and diseases, tooth decay with improved palatability and tissue compatibility, includes an aqueous chlorine dioxide and chlorite ion solution with the chlorite ion predominating in the multiple oxychlorine rinse composition. A method for preparing such antimicrobial oxychlorine oral rinse composition comprising 3 ppm to about 200 ppm of chlorine dioxide, by first preparing an aqueous solution with about 7 to 400 ppm of chlorite ion; then an aqueous acidifying agent concentrate which, upon introduction to the chlorite solution, reduces its pH to about 4.5 to 6.0; then a second aqueous buffer-producing oxidant combination concentrate. The first acidifying agent concentrate is added to the chlorite ion solution and the second aqueous buffer-producing oxidant combination concentrate is added to the acidified chlorite ion solution, producing an antimicrobial oxychlorine oral rinse composition at about 5.0 to 6.8 pH.

Some include chlorine dioxide

Clinical improvement after periodontal tray application of chlorine dioxide gel as an adjunct to scaling and root planing (SRP) in the treatment of ch…

three that were tested contained ****sodium chlorite [rather than actual chlorine dioxide], which significantly reduced hardness and increased surface abrasions***.

Chlorine Dioxide drinking water additive for dental benefits and water bowl cleansing

MICROCHEM_VIRUS_Study June 2020.pdf - human_corona_virus_study.pdf

******* Salivary biomolecules which chemically react with oral rinse oxidant can, at least in principle, serve as potentially significant barriers to these therapeutic properties in the oral environment. Therefore, in this investigation, we have explored the extent of ClO2− consumption by biomolecules which scavenge this agent in human salivary supernatants (HSSs) in vitro.

******{Nasal flushing with Snoot! or DioxiRinse}

**** "The retention of these products' active agent, i.e. greater than 10% of ClO2-, is consumed by HSS biomolecules within recommended 30 second oral rinsing episodes, and hence, the bulk of this oxyhalogen ocidant (greater than 90%) may effectively exert its essential microbicidal, anti-periodontal and oral molodour-neutralising actions."

{CloSYS brand} This in vitro study evaluated the effectiveness of a novel dentifrice containing stabilized chlorine dioxide, sodium lauroyl sarcosinate (sarkosyl), and sodium fluoride in enhancing enamel fluoride uptake, remineralization, pellicle cleaning and inhibiting biofilm regrowth.

(2020)

Request PDF | Influence of chlorine dioxide on cell death and cell cycle of human gingival fibroblasts | The effects of chlorine dioxide (ClO2), sodium hypochlorite (NaOCl), and hydrogen peroxide (H2O2) on cell death and the cell cycle of human... | Find, read and cite all the research you need on ResearchGate

***** {OraCare} "Activated chlorine dioxide" "Simply stated, it strips off more than twice as many electrons from a pathogen. This occurs in a two-step process: First, the reaction causes chlorine dioxide to be reduced to sodium chlorite. Then the sodium chlorite is reduced to sodium chloride, or ordinary table salt and water, which are harmless. The chlorine molecule remains in the substance until the end; that’s why chlorine dioxide does not produce harmful chlorinated substances such as trihalomethanes."

Chlorine dioxide (ClO[2] ) has been recently investigated as a possible root canal irrigant due to its broad spectrum of antimicrobial action, tissue dissolution and smear layer removal properties. Literature is scarce on the effect of chlorine dioxide ...

{Includes use of ethanol} The oral cavity, an essential part of the upper aerodigestive tract, is believed to play an important role in the pathogenicity and transmission of SARS-CoV-2. The identification of targeted antiviral mouth rinses to reduce salivary viral load would contribute ...

View lab results from an in vitro laboratory analysis with CloSYS Ultra Sensitive Oral Rinse and COVID-19 virus. Reduced SARS-CoV-2 (COVID-19 virus) by 98.4 percent.

{CloSys}

OraCare’s Activated Oral Cleanser -chlorine dioxide

"...Further studies are also required to protect teeth, the surface of hydroxyapatite-coated implants, and the surrounding soft tissues from effects of chemical dissolution such as acid erosion due to the low pH of ASC-Gel. "

!! "Results showed *5.25% NaOCl to be most effective* (at dissolving tissue) at both time intervals followed by 2.5% NaOCl at 60 minutes, 10%Ca(OCl)2 and 13% ClO2 at 60 minutes. Least amount of tissue dissolving ability was demonstrated by 5% Ca(OCl)2 and 5% ClO2 at 30 minutes." *****"Mean tissue dissolution by ClO2 was significantly less than NaOCl. The reason for this might also be the low pH of ClO2 as compared to high pH (pH = 12) of NaOCl. In a study by Nishikiori et al,[18] the pH of ClO2 was raised upto 12 by using NaOH and it was found equivalent to NaOCl for dissolving bovine pulp tissue. But according to Deininger et al.[19] ClO2 exhibits biocidal efficacy only over a pH range of 3-9. Between pH 4-7, chlorine exists predominantly as HClO, the active moiety responsible for bacterial inactivation, whereas above pH 9, OCl− predominates.[20] Also the addition of NaOH will result in making the aqueous solution of ClO2 ineffective by breaking it down into sodium chlorate, sodium chlorite and water. Among the ClO2 group, large amount of mean tissue dissolution was demonstrated by 13% ClO2 at 60 minutes.5% ClO2 showed lower pulp dissolving capacity at 30 minutes, followed by 5% ClO2 at 60 minutes and 13% ClO2 at 30 minutes, which were comparable. *****Studies have suggested that !!!!!!!lower the pH !!!!, more time was needed for solution contact for tissue dissolution.***** [6] This might be the reason for less effectiveness of ClO2 in dissolution of pulp tissue at 30 minutes than at 60 minutes. "

***********SARS-CoV-2 --"“ClO2 impacts the coronavirus by its rapid reaction with three of the twenty amino acid residues, cysteine, tyrosine, and tryptophan, found in all protein chains, while essentially not reacting with the others. Since the spike protein contains all three, this could be an important point of attack; their oxidation changes the entire spatial structure of the protein, leading to denaturation." "Sodium chlorite (NaClO2) solution is often wrongly referred to as chlorine dioxide, which was the case with the internally used and harmful MMS drops. Sodium chlorite is absorbed differently from chlorine dioxide, and can reach the kidneys and the liver. In small quantities its toxic effect causes vomiting and diarrhoea, while in larger doses it may lead to kidney failure" "Immune response... takes 8-12 days and if, during this critical phase, too many coronaviruses reach the lungs, reproducing rapidly on its mucous membrane, this may induce a strong and often fatal immune response, called the cytokine storm”. People infected may also inhale the aerosol particles again,"

****!!!**** "medicines (drugs) or medical devices may be used for the treatment (prevention, alleviation, etc.) of human diseases. A drug penetrates inside the body, and influences the processes within the human tissues. However, hyperpure chlorine dioxide is not able to penetrate into the human body but exerts its antimicrobial action only on its surface, against microbial biofims, for example. Therefore, Solumium solutions are not drugs but *******medical devices." full bottle (30ml) of Solumium Dental contains 36 mg of chlorine dioxide. "In root canal treatment... highly volatile Solumium Dental evaporates into any air bubbles, and goes on eliminating the bacteria in the whole treated area." "Daily dose of 24 mg of chlorine dioxide has no clinically or in any other way measurable effect on the human body."