Inquiry must assess how Canada’s fragmented COVID-19 response lost the public’s trust
Now is the time to learn from the COVID-19 response through an action-oriented independent inquiry focused on accountability. Reforms to data generation, access and use are essential.
Pregnant people with COVID-19 are at increased risk of severe illness and death compared
with non-pregnant females of reproductive age (aged 15–49 years).1 Additionally, COVID-19
during pregnancy is associated with increased risk for adverse pregnancy outcomes,
such as preterm birth and stillbirth.1 When mRNA COVID-19 vaccines first became available
in December, 2020, safety data in pregnancy were limited because pregnant people were
excluded from pre-authorisation clinical trials.2 Lack of data and safety concerns
contributed to initially low uptake among pregnant people, which continues to be lower
than uptake among non-pregnant females of reproductive age.
Complications of COVID-19 Vaccines during Pregnancy; a Systematic Review
Rare serious complications have been documented after COVID-19 vaccination as clinical research proceeded and new target populations, such as children and pregnant women, were included. In this study, we attempted to review the literature relevant ...
Here's the science behind the COVID vaccine in pregnancy
Existing evidence on the safety and efficacy of getting a COVID vaccine in pregnancy all points the same way: the shot is important for maternal and fetal health.
COVID-19 vaccine side-effects less likely in pregnant people, says study
Pregnant people experienced lower rates of side-effects from the COVID-19 vaccine than their counterparts who weren't pregnant, a new Canadian study suggests.
Safety of mRNA vaccines administered during the initial 6 months of the US COVID-19 vaccination programme: an observational study of reports to the Vaccine Adverse Event Reporting System and v-safe
Safety data from more than 298 million doses of mRNA COVID-19 vaccine administered
in the first 6 months of the US vaccination programme show that most reported adverse
events were mild and short in duration.
Fact Check: Most cases of myocarditis after COVID-19 vaccines are not irreversible
Medical experts on the basis of evidence so far disagree with claims made on social media that myocarditis following the COVID-19 vaccine is irreversible. Social media claims that “over the years,” many children diagnosed with myocarditis will die are unfounded, representatives from the Myocarditis Foundation say.
An Evidence-Based Approach to Covid-19 Vaccination | NEJM
This article from the FDA compares broad U.S. recommendations on Covid vaccination
with those from other countries and announces the adoption of an evidence-based approach
to such recommendations.
Pfizer vaccine 70 percent effective against omicron hospitalizations: research
A new South African study finds that the two-dose Pfizer-BioNTech COVID-19 vaccine is 70 percent effective at preventing hospitalizations due to the omicron variant.The research publ…
What we know about the safety, efficacy of mRNA vaccines amid recent scrutiny
Infectious disease experts say mRNA vaccines have been studied for decades, they are safe and effective, and were instrumental in saving lives during the COVID pandemic.
Melatonin a Promising Candidate for Prevention and Treatment of COVID-19
A new network medicine study finds that melatonin usage may prevent COVID-19 infection, though large-scale trials are needed. Researcher Feixiong Cheng, PhD, discusses his team’s findings.
Bruce Arthur: Doug Ford’s shaky math, twisted logic block hospital vaccine mandates, and prolong the pandemic
The decision, after weeks of foot-dragging and citing numbers that weren’t backed up, was the latest in a string of moves that give comfort to the anti-vaccine community.
Bruce Arthur: For Doug Ford’s government, the selfish freedom to decide not to be vaccinated trumps the consequences
The provincial government encourages you to get vaccinated. But are they going to force a choice on that? No, they are not. Are they going to try? Not much.
If you are going to make a claim, or counterclaim - otherwise by definition you are not intending a good faith dialogue, and we have no interest in discussions with you.
Where are the Double Blind Placebo Controlled Randomized Trials about Vaccines - VAXOPEDIA
Learn about the role of double-blind, placebo-controlled randomized trials in vaccine research. Explore how they provide reliable evidence on vaccine safety and efficacy.
Tech millionaire Steve Kirsch went from covid trial funder to misinformation superspreader | MIT Technology Review
After boosting unproven covid drugs and campaigning against vaccines, Steve Kirsch was abandoned by his team of scientific advisers—and left out of a job.
My Conversation with Robert F. Kennedy Jr. - by Paul Offit
Twenty years ago, I had a one-hour conversation with RFK Jr. In his current campaign for president, he has referred to that conversation during public appearances. It’s time to set the record straight
Medicine in the Media: Reliable Health Information v. Fake News - HealthyChildren.org
One challenge of parenting is sorting through all available information about children's health. Here are some tips for making sense of all of the messages.
Vaccine Safety: Examine the Evidence - HealthyChildren.org
Vaccines for kids are studied closely before the American Academy of Pediatrics recommends them. Safety evidence is gathered when a new vaccine is made and after it is authorized.
RFK Jr. resurrects an old antivax half-truth about “saline placebos” in randomized controlled trials of vaccines | Science-Based Medicine
RFK Jr. has resurrected the misleading claim that childhood vaccines have never been tested in randomized controlled trials with a saline placebo controls.
Almost none of the vaccines on the list that weren’t licensed based on RCTs using saline controls are not first generation vaccines, which means that it would have been unethical to test them against a saline control.
The bottom line is that, if you trace back the history of the vaccines developed for a disease like, say, measles, you will eventually find the RCT testing the first effective vaccine against it and that vaccine will have had a placebo control. It might not have been saline (although in most cases decades ago it was), but it will have been a placebo that was “inert” with respect to preventing that disease. Also, clinical trial standards have evolved over the last 70 years. If a vaccine was approved 60+ years ago using methodology that today we might consider inadequate, that does not change the calculus when it comes to testing new vaccines against the same disease. Such vaccines can’t ethically be tested against saline placebo.