Antidepressants

Exclusive: Clinical guidelines should change to avoid exposing young people to potentially harmful side-effects, researchers say

New evidence from a Dutch study suggests that population density may influence how people respond to serotonergic antidepressants. Patients in quieter, less populated neighborhoods showed healthier attention patterns, raising questions about how environmental context interacts with treatment for depression.

A large-scale analysis of U.S. mass shootings finds little support for claims that antidepressants cause violent behavior, suggesting most perpetrators were not taking psychiatric medication at the time of their attacks.

People with depression who were more optimistic at the start of treatment—and whose optimism increased during treatment—were more likely to benefit from SSRIs, according to a recent study, raising the possibility of tailoring treatments based on psychological traits.

Selective serotonin reuptake inhibitors are at the centre of a collision between social and biochemical outlooks on depression, finds Andy Extance

Despite claims that antidepressants may be just delivering a placebo effect, three-quarters of people who tried them in a large study said they helped

Depression is a very complex disorder and we simply have no good evidence that antidepressants help sufferers to improve