Autoimmune/Complex

The study is the first large-scale clinical trial to show that a new oral endocrine therapy outperforms the long-standing standard therapies used for early-stage HR-positive/HER2-negative breast cancer.

New research is challenging one of medicine’s oldest assumptions: that cancer must be attacked to be cured. By treating glioblastoma patients with a simple combination of resveratrol and copper, the researchers found dramatic reductions in tumor aggressiveness, cancer biomarkers, immune checkpoints, and stem-cell–related markers—all without side effects. Their approach focuses on “healing” tumors by eliminating harmful cell-free chromatin particles released from dying cancer cells, which normally inflame and worsen the disease. The findings hint at a future where inexpensive nutraceuticals could transform cancer therapy.

Nutrition is a key aspect of autoimmune conditions.

CAR-T therapy might hold the key

A Japanese-led research team has developed AUN, a groundbreaking immune-independent bacterial cancer therapy that uses two harmonized bacteria to destroy tumors even in patients with weakened immune systems. By leveraging the natural synergy between Proteus mirabilis and Rhodopseudomonas palustris, AUN selectively targets cancer cells, reshapes itself within tumors, and avoids harmful side effects like cytokine release syndrome.

Acupuncture and herbal medicine found effective for lung cancer treatment in integrative medicine settings.

Teclistamab therapy shows potential in achieving drug-free remission in patients with refractory autoimmune diseases, with manageable cytokine release syndrome.

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Learn about the latest research on acupuncture from MSK and how our investigators are studying the benefits of acupuncture for relieving the side effects of cancer and its therapies.

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What if your brain is the reason some pain feels unbearable? Scientists at the Salk Institute have discovered a hidden brain circuit that gives pain its emotional punch—essentially transforming ordinary discomfort into lasting misery. This breakthrough sheds light on why some people suffer more intensely than others from conditions like fibromyalgia, migraines, and PTSD. By identifying the exact group of neurons that link physical pain to emotional suffering, the researchers may have found a new target for treating chronic pain—without relying on addictive medications.

The investigational Lyme disease vaccine VLA15 shows favorable safety profile and strong immunogenicity across all age groups, with particularly robust responses in children and adolescents.

Two groundbreaking studies from Northwestern researchers may transform how we treat and understand Lyme disease

2,510 likes, 140 comments - unbiasedscipod on August 14, 2023: "Lyme disease (LD): while a public health concern, rampant misinformation fueled by vocal advocacy organizations has led the public to perceive it as a bigger threat than it is. One of the most pervasive: chronic Lyme disease. LD is a bacterial infection caused by Borrelia burgdorferi (rarely Borrelia mayonii in the US; Borrelia garinii & Borreli afzelii in Europe). In the US, 2 species of ticks can transmit these bacteria: Black-legged & western Black-legged ticks. It is not spread by other ticks, other arthropods, or by other means. Most infections remain localized, cause mild illness, and present with the ‘bulls-eye rash’, erythema migrans. Other symptoms are generic: fever, fatigue, headache, muscle/joint pain, and lymphadenopathy. In ~10-20% of infections (depending on bacterial strain), bacteria can spread elsewhere in the body like large joints and nerves and cause disseminated LD symptoms, which can be painful and debilitating. The good news? The bacteria can be killed with antibiotics. Even without antibiotic treatment, most infections would be eliminated by your immune system. In a small proportion of individuals who TRULY were infected, certain symptoms - fatigue, musculoskeletal pain, insomnia - may last after antibiotic treatment. These are post-treatment Lyme disease syndrome (PTLDS) symptoms, or sequelae, and are a result of the immune response – inflammation created to eliminate bacteria. PTLDS typically resolves over a period of months, like other post-infection sequelae. This is NOT chronic infection. Bacteria are not hiding, persisting, or establishing dormancy or biofilms. Infection does not reactivate over the years. There is NO benefit to taking longer-term antibiotics. Bacteria are eliminated. Chronic Lyme disease is not a medically supported condition, no matter how loud advocacy organizations shout. Unfortunately, chronic Lyme has become a scapegoat for an array of non-specific symptoms even without evidence someone had Lyme to begin with. This prevents people from addressing real causes of their symptoms and undergoing harmful and expensive ‘treatments’, as well as propagating fallacies and undue fear about Lyme to the public.".

11K likes, 527 comments - unbiasedscipod on August 9, 2023: "“Chronic Lyme” is a scapegoat in the ‘alternative health’ & ‘wellness’ industries. Many nonspecific symptoms are falsely attributed to a bacterial infection readily treated with antibiotics. This trend has increased due to celebrity & media attention. We have discussed Lyme pseudoscience extensively, but with recent headlines about Bella Hadid, we must revisit. Bella shared this 2016 ‘lab report’ filled with Lyme misinformation. Here are the most glaring. 1️⃣Urine samples cannot be used to diagnose ANY of these, Lyme or otherwise. Credible expert organizations including Infectious Diseases Society of America are explicit about this. 2️⃣FDA-authorized Lyme tests assess immune responses (antibodies) to Borrelia burgdorferi in blood. There are NO credible Lyme tests that use PCR (what this test claims to use). 3️⃣The test falsely claims the first 4 ‘microbes’ listed are different species of Lyme bacteria. 4️⃣This test “detects” SEVERAL impossible co-infections alongside Lyme: Bartonella bacilliformis only occurs in the Andes Mtns (South America) between 3,000 and 10,000 ft. of elevation. It is transmitted by sand flies, NOT ticks. Bartonella henselae is also NOT spread by ticks, but by fleas (or animal scratch contaminated with infected flea feces). Ehrlichia chaffeensis is transmitted by ticks, but NOT the species that transmits Lyme bacteria. The likelihood Bella was bitten by 4 different arthropods all infected with these bacteria (incl. one only in S. American mountains) is near zero. It is also implausible she has been infected for over 7 years. Self-appointed “Lyme specialists” have gotten rich by selling fake tests to diagnose illnesses that there is zero evidence (clinical or epidemiological) to support. They then prescribe unproven, harmful, long-term, and expensive treatments. Is Bella feeling ill? Possibly! But it is very likely the array of “treatments” for infections she doesn’t have are the cause of that. Unfortunately, celebrities who buy into the myths about Lyme fall prey and legitimize it with their large public platforms. Scientists, credible clinicians, and media outlets all need to help dispel this type of harmful nonsense.".

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Envita is a world-class late-stage cancer treatment center that specializes in treating the most difficult and complex cases.

That chronic Lyme exists in the realm of experience doesn’t mean it isn’t real. When medicine does not acknowledge the reality of the subjective—the thick reality of lived experience—we fall laughably short in our efforts to serve patients. When it comes to tick-borne Lyme disease itself, we all need to expand our horizons. That suffering is real. It must be attended to. But to insist beyond all plausibility that one’s suffering is related to a tick bite is not feminist; it’s absurd. And to prey on suffering people who crave that certainty, offering them expensive, intensive, and dangerous treatments is worse than absurd; it’s cruel.

Vitally important for treatment.

The disease is caused by internal heat toxins which damage the essential substance and invade the bone marrow, resulting in consumption of blood and impairment of Yin.

Acute myeloid leukemia (AML) is a heterogeneous hematological malignancy with historically high mortality rates. The treatment strategies for AML is still in...

Gain insights into leukaemia through the lens of Traditional Chinese Medicine on Me & Qi. Delve into the causes and explore natural TCM remedies for effective relief and wellness.

Cutting-edge cancer treatments are essentially useless for patients barely clinging to life, a new study shows. Chemotherapies, immunotherapies, targeted therap