Cancer in First Nations people in Ontario, Canada: Incidence and mortality, 1991 to 2010
This study aims to measure cancer incidence and mortality rates of Registered First Nations people in Ontario and to look at trends over time, particularly in cancer rates that are targeted by screening programs (cervical, breast, colorectal) or public health interventions (smoking). The federal Indian Register, the Ontario Cancer Registry and the Registered Persons Database were linked to develop a cohort of First Nations people diagnosed with cancer in Ontario.
Comparing cancer incidence, stage at diagnosis and outcomes of First Nations and all other Manitobans: a retrospective analysis - BMC Cancer
Background Globally, epidemiological evidence suggests cancer incidence and outcomes among Indigenous peoples are a growing concern. Although historically cancer among First Nations (FN) peoples in Canada was relatively unknown, recent epidemiological evidence reveals a widening of cancer related disparities. However evidence at the population level is limited. The aim of this study was to explore cancer incidence, stage at diagnosis, and outcomes among status FN peoples in comparison with all other Manitobans (AOM). Methods All cancers diagnosed between April 1, 2004 and March 31, 2011 were linked with the Indian Registry System and five provincial healthcare databases to compare differences in characteristics, cancer incidence, and stage at diagnosis and mortality of the FN and AOM cohorts. Cox proportional hazard regression models were used to examine mortality. Results The FN cohort was significantly younger, with higher comorbidities than AOM. A higher proportion of FN people were diagnosed with cancer at stages III (18.7% vs. 15.4%) and IV (22.4% vs. 19.9%). Cancer incidence was significantly lower in the FN cohort, however, there were no significant differences between the two cohorts after adjusting for age, sex, income and area of residence. No significant trends in cancer incidence were identified in either cohort over time. Mortality was generally higher in the FN cohort. Conclusions Despite similar cancer incidence, FN peoples in Manitoba experience poorer survival. The underlying causes of these disparities are not yet understood, particularly in relation to the impact of colonization and other determinants of health.
High Melanoma Rates in the American Indian and Alaska Native Population—A Unique Challenge
In the Navajo language, cancer is broadly described as łóód dóó nádzi híí, which translates directly as a “sore that does not heal.”1 Accurate determination of cancer incidence in a specified population is a critical first step toward addressing disease burden. Previous studies have shown that...
Melanoma Incidence Rates Among Non-Hispanic American Indian/Alaska Native Individuals, 1999-2019
This cross-sectional study examines invasive cutaneous melanoma incidence rates and trends over time among non-Hispanic American Indian/Alaska Native people.
These viral Korean skincare products are worth the hype (Stylevana AD)
I tested a bunch of viral Korean beauty products - these ones lived up to the hype!This video is sponsored by Stylevana, who stock lots of Korean products. U...
Specific nutrients appear to influence inflammation, synaptic plasticity, and even structural integrity of brain tissue, and may translate into a lower risk ...
Chronic Stress Quietly Speeds Up Immune Aging and Depression
Glyceraldehyde links chronic stress to depression by driving inflammation and telomere shortening, offering a potential biomarker for diagnosis and treatment.
Stress, depression factor into link between insomnia, heavy drinking
A new study suggests that perceived stress and depression factor into the relationship between insomnia and hazardous drinking -- perhaps not a surprise. But because the relationship between insomnia and heavy drinking goes in both directions, the influence of stress or depression depends on which condition came first, the analysis found.
If phase 3 trials of MM120 (lysergide d-tartrate) for anxiety and depression are successful, could the LSD-based drug become the first FDA-approved psychedelic?
What to Know About the Connection Between Blueberries and Memory
lueberries are fascinating to scientists. In humans, the berries have been shown to lower blood pressure and help kids perform better on cognitive tests. In rats, there’s evidence the fruit improves working memory and helps the animals balance.
DIY Microdermabrasion - But Proceed With Caution — LisaLise Pure Natural Skincare
Contrary to dermabrasion (which requires a professional dermatologist), microdermabrasion literally 'skims the surface' and can either be done by a professional or by you. Microdermabrasion can even be done effectively with ingredients you probably already have in your kitchen cupboard. Today, we'r
Neuroprotective Herbs and Active Constituents: Approaches to Preventing Degenerative Diseases
Considerable efforts have been made in recent decades to discover which substances can help prevent serious diseases and even limit the effects of the aging process. Foremost in this area has been research into the role of antioxidants, which come in numerous forms, such as vitamins, minerals, phenolic constituents, and sulfur compounds, from both foods and herbs. Several herbal teas appear of potential benefit, including the popular Rooibos tea of South Africa. Ordinary kitchen spices, including rosemary, basil, turmeric, and cumin, have been shown to have potent antioxidant action.
US Dementia Cases Projected to Double Within 40 Years
The number of US adults who will develop dementia each year is projected to increase from approximately 514,000 in 2020 to about1 million in 2060, new research shows.
The Benefits of Seasonal Living for Longevity | Well+Good
Living seasonally, or aligning your life to nature's seasons, offers plenty of longevity benefits. Learn from experts about how to do this in five key longevity-boosting realms.
Ketamine's rapid antidepressant effects traced to overlooked brain cells
Researchers found that ketamine reduces "giving up" behavior in zebrafish by altering astrocyte activity, suggesting its antidepressant effects involve non-neuronal brain cells and promoting resilience against futility-induced passivity.