Digital Gems

Digital Gems

2442 bookmarks
Newest
Pandemic Prompts Rise in Poverty to Levels Unprecedented in Recent Decades and Sharply Affects Inequality and Employment | Press Release | Economic Commission for Latin America and the Caribbean
Pandemic Prompts Rise in Poverty to Levels Unprecedented in Recent Decades and Sharply Affects Inequality and Employment | Press Release | Economic Commission for Latin America and the Caribbean
In a new annual report, ECLAC estimates that the total number of poor people rose to 209 million by the end of 2020, which is 22 million more people than in the previous year. In addition, it calls for creating a new welfare state.
Pandemic Prompts Rise in Poverty to Levels Unprecedented in Recent Decades and Sharply Affects Inequality and Employment | Press Release | Economic Commission for Latin America and the Caribbean
Reduced sensitivity of SARS-CoV-2 variant Delta to antibody neutralization | Nature
Reduced sensitivity of SARS-CoV-2 variant Delta to antibody neutralization | Nature
The SARS-CoV-2 B.1.617 lineage was identified in October 2020 in India1–5. It has since then become dominant in some indian regions and UK and further spread to many countries6. The lineage includes three main subtypes (B1.617.1, B.1.617.2 and B.1.617.3), harbouring diverse Spike mutations in the N-terminal domain (NTD) and the receptor binding domain (RBD) which may increase their immune evasion potential. B.1.617.2, also termed variant Delta, is believed to spread faster than other variants. Here, we isolated an infectious Delta strain from a traveller returning from India. We examined its sensitivity to monoclonal antibodies (mAbs) and to antibodies present in sera from COVID-19 convalescent individuals or vaccine recipients, in comparison to other viral strains. Variant Delta was resistant to neutralization by some anti-NTD and anti-RBD mAbs including Bamlanivimab, which were impaired in binding to the Spike. Sera from convalescent patients collected up to 12 months post symptoms were 4 fold less potent against variant Delta, relative to variant Alpha (B.1.1.7). Sera from individuals having received one dose of Pfizer or AstraZeneca vaccines barely inhibited variant Delta. Administration of two doses generated a neutralizing response in 95% of individuals, with titers 3 to 5 fold lower against Delta than Alpha. Thus, variant Delta spread is associated with an escape to antibodies targeting non-RBD and RBD Spike epitopes.
Reduced sensitivity of SARS-CoV-2 variant Delta to antibody neutralization | Nature
5 Psychological Benefits of Walking
5 Psychological Benefits of Walking
Recently, I had gone through a bout of stress - I had taken on too much work, injured my back, and was generally feeling out of touch with myself. I’ll admit that there were times when I was preaching the importance of self-care to a crowd...in the middle of a 60-hour work week. And the clumps
5 Psychological Benefits of Walking
Mad Men. Furious Women.
Mad Men. Furious Women.
Far from dissipating over the last decade, misogyny in the ad industry has simply mutated into something insidious, invisible, lurking in the shadows. It’s time to fire up the floodlights.
Mad Men. Furious Women.