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Cialis, often known by its generic name tadalafil, is another well-known PDE5 inhibitor used to treat ED. Its prolonged duration of effect makes it stand out among other tablets for erectile dysfunction. Because it remains effective for up to 36 hours, Cialis is often referred to as "the weekend pill." You should always choose . With its efficacy lasting for so much longer, couples might feel free to be more open and creative in their sexual sessions. Depending on the patient's needs, Cialis can be taken once daily, twice daily, or even three times a day.