Sometimes my audio interface just would not work after my Macbook woke up from sleep. The solution is to reset the audio subsystem in MacOS.

Some users have experienced an issue where their Mac's Bluetooth keyboard is lagging. The keyboard seems slow to respond; when you type, there is a delay

Use Erase All Content and Settings to quickly and securely erase all of your settings, data, and apps, while maintaining the operating system currently installed.