Thinking (draft) — Laura Deming
public personal library
How Meditation Changes Productivity
Carl Sagan's Cosmos: A Personal Voyage (1980) Full Documentary
THE SAGAN SERIES - The Frontier Is Everywhere
A Syntopicon - Wikipedia
In the end, the Syntopicon would require over 400,000 man-hours of reading[4] and cost over two million dollars.
The process of cataloging each appearance of one of the “Great Ideas” in all 431 works by 71 authors in the collection was so arduous that the Syntopicon nearly did not make it to print. Before it even came time to print, the budget had topped a million dollars and there was not even “a penny for paper” left.
He worked with a team of over 100 readers who met twice a week for years to discuss the readings and the ideas within them. Among his editorial team was a young Saul Bellow.
Research Note: Understanding Australia’s declining R&D performance
Australia’s business R&D intensity grew during the 1990s and peaked in years of the mining boom when it reached 1.38% of industry value-added and 1.28% of GDP. However, the rate then started to fall, and has been declining ever since. It is now at a meagre 0.93% – is at its lowest level in two decades.
Had Australia maintained our peak rate from the mining boom, business R&D would have been $29.8 billion in last financial year: $9.1 billion or 44% higher than it actually was.
The R&D intensity of the OECD group has grown from 2.3% to 2.7% of GDP since 2008. Particularly large increases occurred in the UK and US, while France, Germany and Japan all maintained high but steady rates.
Research and Experimental Development, Government and Private Non-Profit Organisations, Australia, 2022-23 financial year
In 2022-23, the greatest contributions to PNPERD by FoR classification were recorded in:
Biomedical and Clinical Sciences at $1,140 million (72%),
Health Sciences at $228 million (14%).
Compared to 2020-21, the largest dollar increases in FoR were recorded in:
Health Sciences up $91 million (67%),
Biomedical and Clinical Sciences up $76 million (7%).
In 2022-23, GOVERD included:
$4,022 million (93%) in Current expenditure,
$322 million (7%) in Capital expenditure.
Compared to 2020-21, GOVERD increased by:
20% in current price terms,
9% in chain volume terms.
Expenditure on R&D performed by Australian government organisations in 2022-23 was $4,344 million, up $726 million compared to 2020-21.
Expenditure on R&D performed by Australian private non-profit (PNP) organisations in 2022-23 was $1,595 million, up $196 million compared to 2020-21.
In 2022-23, the greatest contributions to GOVERD by FoR classification were recorded in:
Agricultural, Veterinary and Food Sciences at $636 million (15%),
Biomedical and Clinical Sciences at $551 million (13%),
Engineering at $485 million (11%).
Compared to 2020-21, the largest dollar increases in FoR were recorded in:
Environmental Sciences up $173 million (73%),
Information and Computing Sciences up $107 million (32%).
In 2022-23, the greatest contributions to GOVERD by SEO classification were recorded in:
Health at $806 million (19%),
Defence at $753 million (17%).
Compared to 2020-21, the largest dollar increases in SEO were recorded in:
Defence up $138 million (23%),
Health up $136 million (20%).
How I learned to program
Hiring and the market for lemons
The Weary Blues - Langston Hughes
Learning Dynamical Systems With Hit-and-Run Random Feature Maps
The Carrier Bag Theory of Fiction - Ursula K Le Guin
Quantitative and Systems Pharmacology in the Post-genomic Era: New Approaches to Discovering Drugs and Understanding Therapeutic Mechanisms. An NIH White Paper by the QSP Workshop Group
Applications of Quantitative Systems Pharmacology in Model‐Informed Drug Discovery: Perspective on Impact and Opportunities
An Algorithm Is a Living Thing
On Notes, there’s no one looking after your brain. There’s no one protecting you from clickbait and softcore thirst traps. There’s no one deciding what’s worth your time. In fact, the algorithm especially doesn’t care. It wants to steal your time.
Letter from a Region in My Mind, by James Baldwin | The New Yorker
Owing to the way I had been raised, the abrupt discomfort that all this aroused in me and the fact that I had no idea what my voice or my mind or my body was likely to do next caused me to consider myself one of the most depraved people on earth. Matters were not helped by the fact that these holy girls seemed rather to enjoy my terrified lapses, our grim, guilty, tormented experiments, which were at once as chill and joyless as the Russian steppes and hotter, by far, than all the fires of Hell.
Meta’s Waterworth: Should we be hyperventilating about hyperscalers’ hyper-infrastructure?
Existing international frameworks – such as those administered by the International Telecommunications Union (ITU) or under the aegis of the United Nations – were never designed to regulate hyperscaler control over critical infrastructure.
The question we must ask ourselves is how much power we are willing to surrender to a few multi-billionaires, especially those tethered to an increasingly unpredictable US administration.
When Lilacs Last in the Dooryard Bloom’d
A socratic dialogue over the utility of DNA language models (Part 2 of 2)
Genetic circuit design automation
Genomic mining of prokaryotic repressors for orthogonal logic gates - Nature Chemical Biology
Things Of Interest
Stripe annual letter 2024
How to Create an Anki Deck That Maximizes Learning
How to Use Anki: An Efficient Tutorial for Beginners
Obituary: Gene Hackman, Oscar-winning star of 'Superman' and 'Unforgiven,' dies at 95
"You go through stages in your career that you feel very good about yourself. Then you feel awful, like, 'Why didn't I choose something else?'" Hackman reflected to GQ magazine in 2011, seven years after his retirement from acting. "But overall I'm pretty satisfied that I made the right choice when I decided to be an actor. I was lucky to find a few things that I could do well as an actor and that I could look at and say, 'Yeah, that's all right.'"
Note from Brad — Brad Mehldau
Beyond NISQ: The Megaquop Machine
Genetic Design in 7 Experiments
But we’ll first have to study biology as an intricate whole, and understand how our own designs fit into the context of lifeforms that have evolved, without us, over billions of years. Time will tell.
Paris Review - The Art of Fiction No. 196, Kazuo Ishiguro
All you’ve discovered is that the search is difficult, and you still have a duty to keep on searching.
This might seem destructive, but the idea is that the nature of what is good is elusive.
But there is no Socrates figure. They are their own Socrates.