Application of Procalcitonin for the Rapid Diagnosis of Clostridioides difficile Infection in Patients with Inflammatory Bowel Disease
Background: The incidence of Clostridioides difficile infection (CDI) has increased in recent years in patients with inflammatory bowel disease (IBD). C. difficile is a toxin-producing bacterium, and CDI results in the worsening of underlying IBD, increasing the risk of IBD trea …
Frequency of Diarrhea, Stool Specimen Collection and Testing, and Detection of Clostridioides Difficile Infection Among Hospitalized Adults in the Muenster/Coesfeld Area, Germany
Clostridioides difficile infection (CDI) often manifests as diarrhea, particularly in adults of older age or with underlying comorbidities. However, only severe cases are notifiable in Germany. Moreover, failure to collect a stool specimen from inpatients with diarrhea or incomplete testing may lead …
Accuracy of diagnostic assays for the detection of Clostridioides difficile: A systematic review and meta-analysis
This meta-analysis demonstrated that EIAs could be reliable methods for detecting CDI based on their sensitivity, specificity, time and cost-effectiveness, and simplicity in the procedure. Further work to improve rapid tests would benefit from improvements to the methodology.
Evaluation of two molecular detection platforms for gastroenteritis ... - Nature.com
Scientific Reports - Evaluation of two molecular detection platforms for gastroenteritis pathogens in treated sewage water in the Eastern province of Saudi Arabia
Rapid-format recombinant antibody-based methods for the diagnosis of Clostridioides difficile infection: Recent advances and perspectives
Clostridioides difficile, the most common cause of nosocomial diarrhea, has been continuously reported as a worldwide problem in healthcare settings. Additionally, the emergence of hypervirulent strains of C. difficile has always been a critical concern and led to continuous efforts to …
New GutAlive®, the anaerobic microbiome collection kit
GutAlive®, the unique user-friendly, high-capacity device for stool collection sampling and transport in anaerobic conditions that ensures sample stability
Clostridium Difficile Diagnostics Market Detailed In New Research ... - Digital Journal
Coherent Market Insights provides an encyclopedic study of the Clostridium Difficile Diagnostics Market with holistic insights into important factors and aspects impacting the future growth of the market. The Clostridium Difficile Diagnostics Market has been analyzed for the forecast period 2022-2028 and the historical period 2017-2022. To help players gain a thorough understanding of the Clostridium Difficile […]
New paper from our lab by lead author Quinten Ducarmon, in @CMIJournal (also w/ @edkuijper2). TL/DR; a commercial diagnostic test failed to detect recurrent CDI due to a cryptic clade C-II RT151 #cdiff isolate. A🧵with more info👇https://t.co/rGtq0taNBT— Wiep Klaas Smits (@SmitsLab) December 12, 2022
Diagnosis and Management of C. difficile Infection (CDI) in Patients with Inflammatory Bowel Disease
Dr. Abraham discusses importance of differential diagnosis of C. difficile infection (CDI) in patients with IBD and how both IBD and CDI should be managed.
Ribotyping of Clostridioides difficile in the Liberec Regional Hospital: a tertiary health care facility - PubMed
The ribotyping of Clostridioides difficile is one of the basic methods of molecular epidemiology for monitoring the spread of C. difficile infections. In the Czech Republic, this procedure is mainly available in university hospitals. The introduction of ribotyping in a tertiary health care facility …
Comparison of clinical severity, genotype and toxin gene expression of binary toxin-producing Clostridioides difficile clinical isolates in Japan - PubMed
The emerging Clostridioides difficile strain BI/NAP1/027 has been reported to be associated with more severe clinical symptoms and higher mortality rates, thought in part due to production of a novel binary toxin alongside conventional A and B toxins. However, recent studies suggest that this …
Take a minute to read our story about how our IP team partnered with our ED physicians at Emory Midtown to detect C diff early! #infectionprevention #APIC #cdiff
Take a minute to read our story about how our IP team partnered with our ED physicians at Emory Midtown to detect C diff early! #infectionprevention #APIC #cdiff https://t.co/PVPLtPDa5z— Jill Holdsworth (@JillHolds) November 18, 2022
Clinical Decision Support Systems to Reduce Unnecessary Clostridioides difficile Testing Across Multiple Hospitals - PubMed
CCDS systems reduced unnecessary C. difficile testing and were perceived positively by HCPs when integrated into their workflow and when displaying relevant patient-specific information needed for decision making.
A2. We utilize our EMR to have our C. diff stool test orders cross check the medication list to prevent providers from ordering #cdiff stool tests on patients who received a laxative in the last 48 hoursto decrease inappropriate testing #USAAW22 #AntimicrobialResistance— Veronica Zafonte (@VBZafonte) November 16, 2022
Comparative Evaluation of Luminex xTAG® Gastrointestinal Pathogen Panel and Direct-From-Stool Real-Time PCR for Detection of C. difficile Toxin tcdB in Stool Samples from a Pediatric Population - PubMed
Detection of Clostridioides difficile toxins in patients with gastroenteritis has increasingly been accomplished through the use of enteric multiplex syndromic panels. Comparisons of the performance of these panels to both direct-from-stool (DFS) and culture-enriched stools followed by polyme …
Comparative Evaluation of Luminex xTAG® Gastrointestinal Pathogen Panel and Direct-From-Stool Real-Time PCR for Detection of C. difficile Toxin tcdB in Stool Samples from a Pediatric Population - PubMed
Detection of Clostridioides difficile toxins in patients with gastroenteritis has increasingly been accomplished through the use of enteric multiplex syndromic panels. Comparisons of the performance of these panels to both direct-from-stool (DFS) and culture-enriched stools followed by polyme …
SEE the DIFFerence: Reducing Unnecessary C. difficile Orders Through Clinical Decision Support in a Large, Urban Safety-Net System - PubMed
Using only an electronic health record intervention, we successfully decreased C. difficile orders after 72 hours of admission in a large, safety-net system. Variation existed among hospitals and by provider type.
The accuracy of fully automated algorithms for surveillance of healthcare-onset Clostridioides difficile infections in hospitalized patients
We developed and validated a set of fully automated surveillance algorithms for healthcare-onset CDI using electronic health records. In a validation data set of 750 manually annotated admissions, the algorithm based on International Classification of Disease, Tenth Revision (ICD-10) code A04 …
Diagnosis and Management of C. difficile Infection (CDI) in Patients with Inflammatory Bowel Disease - Pharmacy Times
Dr. Abraham discusses importance of differential diagnosis of C. difficile infection (CDI) in patients with IBD and how both IBD and CDI should be managed.
Clostridium Difficile Diagnostics and Treatment Market Forecasts for industry growth by manufacturers, nations, type, and application in the Market Report 2022–2028 | Roche AG, Thermo Fisher Scientific Inc., Merck & Co., Pfizer, Inc., - Digital Journal
Clostridium Difficile Diagnostics and Treatment Market Insights, and Upcoming Business Opportunities 2022-2030 By Stratagem Market Insights the extensive research on Clostridium Difficile Diagnostics and Treatment Market is a clear picture of all the essential factors that are expected to drive the market considerably. A thorough study of the Market helps the buyers of the report, customers, […]
Comparison of commercial assays and two-step approach to detect Clostridioides difficile in South Africa - PubMed
The C. DIFF QUIK CHEK COMPLETE, in a two-step approach with the Xpert C. difficile, performed similarly to the NAATs on their own and offer advantages in terms of cost and workflow in low-resource settings.
Is diagnostic stewardship possible in solid organ transplantation? - PubMed
Bundled interventions focused on appropriate C. difficile testing can result in a significant decrease in testing and clinical diagnosis of C. difficile infection without any harms related to delay in diagnosis. In otherwise stable renal transplant recipients after the first month of transplant, scr …
Agree -good data & @ESCMID guidelines - test all - don’t wait to be asked - missing #cdiff puts other patients at risk of cross infection @RCSI_Micro @EdKuijper2 @kerrieanndavies https://t.co/BkVbXYxuqf— Prof. Fidelma Fitzpatrick (@FfitzP) October 17, 2022
Reference Susceptibility Testing and Genomic Surveillance of Clostridioides difficile, United States, 2012-17 - PubMed
Elevated MICs to antibiotics used for treatment of C. difficile infection were rare and there was no increase in MICs over time. The lack of vanA/B genes or mutations consistently associated with elevated vancomycin MICs suggests there are multifactorial mechanisms of resistance. Ongoing surveillanc …