C Diff Diagnosis

C Diff Diagnosis

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A Bioluminescent Sensor for Rapid Detection of PPEP-1, a Clostridioides difficile Biomarker
A Bioluminescent Sensor for Rapid Detection of PPEP-1, a Clostridioides difficile Biomarker
Current assays for Clostridioides difficile in nonhospital settings are outsourced and time-intensive, resulting in both delayed diagnosis and quarantining of infected individuals. We designed a more rapid point-of-care assay featuring a "turn-on" bioluminescent readout of a C. difficile …
·pubmed.ncbi.nlm.nih.gov·
A Bioluminescent Sensor for Rapid Detection of PPEP-1, a Clostridioides difficile Biomarker
Phenotypical and Genotypical Comparison of Clostridium difficile Isolated from Clinical Samples: Homebrew DNA Fingerprinting versus Antibiotic Susceptibility Testing (AST) and Clostridial Toxin Genes
Phenotypical and Genotypical Comparison of Clostridium difficile Isolated from Clinical Samples: Homebrew DNA Fingerprinting versus Antibiotic Susceptibility Testing (AST) and Clostridial Toxin Genes
DNA fingerprinting studies represent a powerful tool in surveying hypervirulent C. difficile strains in clinical settings. Resistance to vancomycin and metronidazole, as first-line antibiotics, necessitate accomplishment of proper control strategies and also prescription of tigecycline as a m …
·pubmed.ncbi.nlm.nih.gov·
Phenotypical and Genotypical Comparison of Clostridium difficile Isolated from Clinical Samples: Homebrew DNA Fingerprinting versus Antibiotic Susceptibility Testing (AST) and Clostridial Toxin Genes
COMPARISON OF WHOLE GENOME SEQUENCE-BASED METHODS AND PCR RIBOTYPING FOR SUBTYPING OF Clostridioides difficile
COMPARISON OF WHOLE GENOME SEQUENCE-BASED METHODS AND PCR RIBOTYPING FOR SUBTYPING OF Clostridioides difficile
Clostridioides difficile is the most common cause of antibiotic-associated gastrointestinal infections. Capillary-electrophoresis (CE)-PCR ribotyping is currently the gold standard for C. difficile typing but lacks discriminatory power to study transmission and outbreaks in detail. New …
·pubmed.ncbi.nlm.nih.gov·
COMPARISON OF WHOLE GENOME SEQUENCE-BASED METHODS AND PCR RIBOTYPING FOR SUBTYPING OF Clostridioides difficile
Detection of potential enteric pathogens in children with severe acute gastroenteritis using the filmarray: Results from a three - years hospital-based survey in Northern Italy
Detection of potential enteric pathogens in children with severe acute gastroenteritis using the filmarray: Results from a three - years hospital-based survey in Northern Italy
Acute gastroenteritis (AGE) are leading causes of morbidity and mortality in children. Therefore, rapid pathogens identification is needed. The AGE aetiology was investigated from 2018 to 2020 in 2,066 children in Parma (Italy) by FilmArray Gastrointestinal Panel and Enterovirus-targeting RT-PCR. Pa …
·pubmed.ncbi.nlm.nih.gov·
Detection of potential enteric pathogens in children with severe acute gastroenteritis using the filmarray: Results from a three - years hospital-based survey in Northern Italy
Pediatric Clostridioides difficile Infection: Diagnosis and Diagnostic Stewardship
Pediatric Clostridioides difficile Infection: Diagnosis and Diagnostic Stewardship
Although the pathogenesis of Clostridioides difficile infection (CDI) is complex and incompletely understood, it is believed that the elaboration of C. difficile toxins is necessary for disease. There are a variety of tests available for the detection of both the C. difficile organism and its toxins …
·pubmed.ncbi.nlm.nih.gov·
Pediatric Clostridioides difficile Infection: Diagnosis and Diagnostic Stewardship
The Laboratory Diagnosis of Clostridioides difficile Infection: An update of current laboratory practice
The Laboratory Diagnosis of Clostridioides difficile Infection: An update of current laboratory practice
Clostridioides difficile can cause colitis and is associated with hospital acquired infections. The C. difficile infection (CDI) is due to production of toxins A and B which bind to epithelial cell surface receptors and triggers signaling pathways, leading to loss of epithelial barrier function, apo …
·pubmed.ncbi.nlm.nih.gov·
The Laboratory Diagnosis of Clostridioides difficile Infection: An update of current laboratory practice
RT @GeneticAnalysis: [patent] Genetic Analysis AS awarded an important US #patent covering a #companiondiagnostics method for optimizing #I…
RT @GeneticAnalysis: [patent] Genetic Analysis AS awarded an important US #patent covering a #companiondiagnostics method for optimizing #I…
[patent] Genetic Analysis AS awarded an important US #patent covering a #companiondiagnostics method for optimizing #IBS interventions.A #diagnostic method to be used to determine the likelihood that a patient with IBS will respond to treatment with a low-#FODMAP diet or #FMT pic.twitter.com/gm8Kl4246g— Genetic Analysis AS (@GeneticAnalysis) October 29, 2021
·twitter.com·
RT @GeneticAnalysis: [patent] Genetic Analysis AS awarded an important US #patent covering a #companiondiagnostics method for optimizing #I…
New Test Ups Ability to ID C. Difficile
New Test Ups Ability to ID C. Difficile
Researchers used a novel, highly sensitive test to measure the amount of toxin produced by C. difficile in the stool of patients with suspected infections.
·clpmag.com·
New Test Ups Ability to ID C. Difficile
Systematic Review on the Correlation of Quantitative PCR Cycle Threshold Values of Gastrointestinal Pathogens With Patient Clinical Presentation and Outcomes
Systematic Review on the Correlation of Quantitative PCR Cycle Threshold Values of Gastrointestinal Pathogens With Patient Clinical Presentation and Outcomes
Background: Quantitative (q) polymerase chain reaction (PCR) cycle threshold (Ct) values represent the number of amplification cycles required for a positive PCR result and are a proxy of pathogen quantity in the tested sample. The clinical utility of Ct values remains unclear for gastrointes …
·pubmed.ncbi.nlm.nih.gov·
Systematic Review on the Correlation of Quantitative PCR Cycle Threshold Values of Gastrointestinal Pathogens With Patient Clinical Presentation and Outcomes
Rapid ultra-sensitive diagnosis of clostridium difficile infection using a SERS-based lateral flow assay
Rapid ultra-sensitive diagnosis of clostridium difficile infection using a SERS-based lateral flow assay
Clostridium difficile (C. diff) infection is one of the most contagious diseases associated with high morbidity and mortality rates in hospitalised patients. Accurate diagnosis can slow its spread by determining the most effective treatment. Herein, we report a novel testing platform as a proof-of-c
·pubs.rsc.org·
Rapid ultra-sensitive diagnosis of clostridium difficile infection using a SERS-based lateral flow assay
Deconstructing the urinalysis: A novel approach to diagnostic and antimicrobial stewardship
Deconstructing the urinalysis: A novel approach to diagnostic and antimicrobial stewardship
The extensive use of the urinalysis for screening and monitoring in diverse clinical settings usually identifies abnormal urinalysis parameters in patients with no suspicion of urinary tract infection, which in turn triggers urine cultures, inappropriate antimicrobial use, and associated harms like …
·pubmed.ncbi.nlm.nih.gov·
Deconstructing the urinalysis: A novel approach to diagnostic and antimicrobial stewardship
Evaluation of polymerase chain reaction-based open reading frame typing method for the clonality investigation of Clostridioides difficile isolates
Evaluation of polymerase chain reaction-based open reading frame typing method for the clonality investigation of Clostridioides difficile isolates
Here, we assessed the utility of a polymerase chain reaction-based open reading frame typing assay for investigating the clonality of Clostridioides difficile isolates. This assay has a higher discriminatory power than multi-locus sequence typing for molecular epidemiological analysis of C. difficil …
·pubmed.ncbi.nlm.nih.gov·
Evaluation of polymerase chain reaction-based open reading frame typing method for the clonality investigation of Clostridioides difficile isolates
More Advocacy Needed for FMT as an IBD Treatment
More Advocacy Needed for FMT as an IBD Treatment
Healthcare provider knowledge on fecal microbiota transplantation as a treatment for inflammatory bowel disease is still lacking.
·hcplive.com·
More Advocacy Needed for FMT as an IBD Treatment
Breath Biomarker discovery for C. difficile
Breath Biomarker discovery for C. difficile
C. difficile is a leading cause of hospital-acquired diarrhea and in some cases can be dangerous. VOCs produced metabolically and exhaled on breath could be useful to diagnose this infection.
·owlstonemedical.com·
Breath Biomarker discovery for C. difficile
Thread by @Darcy_ID_doc on Thread Reader App – Thread Reader App
Thread by @Darcy_ID_doc on Thread Reader App – Thread Reader App
Thread by @Darcy_ID_doc: #IDTwitter DarcyDoesC.diff Or #Cdiff pearls Or how I approach C. diff in light of new guidelines PCR tests are very sensitive but specificity stinks Be sure of appropriate clinical context ...…
·threadreaderapp.com·
Thread by @Darcy_ID_doc on Thread Reader App – Thread Reader App
Evaluation of an immunochromatographic test for the detection of glutamate dehydrogenase for the diagnosis of Clostridioides (Clostridium) difficile infection in dogs
Evaluation of an immunochromatographic test for the detection of glutamate dehydrogenase for the diagnosis of Clostridioides (Clostridium) difficile infection in dogs
This study aimed to evaluate an immunochromatographic test used to detect glutamate dehydrogenase (GDH) for the diagnosis of Clostridium difficile infection (CDI) in dogs. Fecal samples of 119 diarrheic dogs were subjected to toxigenic culture as the "gold standard" method and to GDH detection (Ecod …
·pubmed.ncbi.nlm.nih.gov·
Evaluation of an immunochromatographic test for the detection of glutamate dehydrogenase for the diagnosis of Clostridioides (Clostridium) difficile infection in dogs
Kicking off #IBDBoston with @DrJessicaA talking about how to diagnose #cdiff in the #IBD patient: first GDH or PCR test and if positive, c diff +; if not, another organism needs to be identified.
Kicking off #IBDBoston with @DrJessicaA talking about how to diagnose #cdiff in the #IBD patient: first GDH or PCR test and if positive, c diff +; if not, another organism needs to be identified.
Kicking off #IBDBoston with @DrJessicaA talking about how to diagnose #cdiff in the #IBD patient: first GDH or PCR test and if positive, c diff +; if not, another organism needs to be identified. pic.twitter.com/SxKhaR7vLy— Tina ✨ Own Your Crohn’s (@ownyourcrohns) September 24, 2021
·twitter.com·
Kicking off #IBDBoston with @DrJessicaA talking about how to diagnose #cdiff in the #IBD patient: first GDH or PCR test and if positive, c diff +; if not, another organism needs to be identified.
Clostridium difficile: The Story Continues on Vimeo
Clostridium difficile: The Story Continues on Vimeo
Clostridium difficile: The Story Continues Globally, Clostridium difficile is one of the most common causes of healthcare-associated infections in hospitals. Recently, focus of C. difficile testing has moved from identification of the organism to detecting the toxins that cause the disease. This webinar will review the updated 2017 C.difficile guidelines and recommendations from the Infectious Disease Society of America (IDSA) and the Society for Healthcare Epidemiology of America (SHEA) and describe how these updates apply to the microbiology laboratory. Speaker: Margie Morgan, PhD D(ABMM) Director Microbiology, Professor of Pathology and Laboratory Medicine Cedars-Sinai Medical Center
·vimeo.com·
Clostridium difficile: The Story Continues on Vimeo