C Diff Diagnosis

Here, we assessed the utility of a polymerase chain reaction-based open reading frame typing assay for investigating the clonality of Clostridioides difficile isolates. This assay has a higher discriminatory power than multi-locus sequence typing for molecular epidemiological analysis of C. difficil …

The results of PCR capillary-based electrophoresis ribotyping in the studied samples showed a high prevalence of RT176 and 001.

Healthcare provider knowledge on fecal microbiota transplantation as a treatment for inflammatory bowel disease is still lacking.

The companies plan to combine testing for infectious diseases and cancers in one multiplex instrument targeted toward decentralized settings.

C. difficile is a leading cause of hospital-acquired diarrhea and in some cases can be dangerous. VOCs produced metabolically and exhaled on breath could be useful to diagnose this infection.

Thread by @Darcy_ID_doc: #IDTwitter DarcyDoesC.diff Or #Cdiff pearls Or how I approach C. diff in light of new guidelines PCR tests are very sensitive but specificity stinks Be sure of appropriate clinical context ...…

This study aimed to evaluate an immunochromatographic test used to detect glutamate dehydrogenase (GDH) for the diagnosis of Clostridium difficile infection (CDI) in dogs. Fecal samples of 119 diarrheic dogs were subjected to toxigenic culture as the "gold standard" method and to GDH detection (Ecod …

Kicking off #IBDBoston with @DrJessicaA talking about how to diagnose #cdiff in the #IBD patient: first GDH or PCR test and if positive, c diff +; if not, another organism needs to be identified. pic.twitter.com/SxKhaR7vLy— Tina ✨ Own Your Crohn’s (@ownyourcrohns) September 24, 2021

Clostridium difficile: The Story Continues Globally, Clostridium difficile is one of the most common causes of healthcare-associated infections in hospitals. Recently, focus of C. difficile testing has moved from identification of the organism to detecting the toxins that cause the disease. This webinar will review the updated 2017 C.difficile guidelines and recommendations from the Infectious Disease Society of America (IDSA) and the Society for Healthcare Epidemiology of America (SHEA) and describe how these updates apply to the microbiology laboratory. Speaker: Margie Morgan, PhD D(ABMM) Director Microbiology, Professor of Pathology and Laboratory Medicine Cedars-Sinai Medical Center

As rates of C. difficile infection decline, emphasis is now on improving test utilization and a quest for improved diagnostic approaches. These approaches may involve implementation of technologies that improve toxin testing, predict patients likely to have disease and/or a severe outcome, and harne …

The new assay was 100% on both sensitivity and specificity for detecting C difficile infections from rectal swabs.

Panel of gastroenterologists share their perspectives regarding the diagnostic work-up for patients who may have symptoms suggestive of IBD.

The quality of fecal specimens is one of the factors responsible for successful Clostridioides difficile infection (CDI) diagnosis. The quality depends largely on the storage conditions, including the temperature and time period. In this study, we organized the outputs of previous studies, fi …

The test runs on the firm's MultiPath Analyzer for single molecule counting to detect C. difficile toxins A and B.

@IbukunMD @JessieSeidelman @beckyasmith79 and team in pursuit of the holy grail -- improving #cdiff testing. pic.twitter.com/Lz98EIHsf1— DICON (@DICON_duke) June 8, 2021

Clostridioides difficile infection (CDI) is an important infectious cause of antibiotic-associated diarrhea, with significant morbidity and mortality. Current diagnostic algorithms are based on identifying toxin by enzyme immunoassay (EIA) and toxin gene by real-time polymerase chain reaction (PCR) …

Clostridioides difficile (C. diff) is the leading cause of gastroenteritis-associated death in North America, and infects around half a million Americans annually. While most people affected will

We sought to determine how often patients with a negative toxin enzyme immunoassay following a positive nucleic acid amplification test for Clostridioides difficile infection (CDI) were treated for CDI in Veterans Affairs facilities. From October 2018 through March 2021, 702 (29.5%) of 2,374 unique …

Overall, the automated CCNA provides a specific, sensitive, and reproducible tool to support determination of CDI epidemiology or the efficacy of interventions such as vaccines.

First Light Diagnostics is developing and commercializing breakthrough automated diagnostic products for rapidly detecting infections and determining optimal treatment. The company announced today that the US Food and Drug Administration (FDA) has cleared its SensiTox™ C. difficile Toxin Test along with its proprietary MultiPath Analyzer to be marketed in the US.