Immune-mediated food reactions in irritable bowel syndrome - ScienceDirect
Irritable bowel syndrome (IBS) is a chronic functional gastrointestinal disorder characterized by recurrent abdominal pain and an altered defecation p…
Soy protein diet increases susceptibility to Clostridioides difficile infection - News-Medical.Net
According to a recent study published in the journal Cell Reports, a diet rich in soy protein increases human Clostridioides difficile susceptibility by increasing the gut amino acids (AAs) levels and promoting the growth of Lactobacillus.
Dietary-protein sources modulate host susceptibility to Clostridioides difficile infection through the gut microbiota
Clostridioides difficile causes nosocomial antibiotic-associated diarrhea on a global scale. Susceptibility to C. difficile infection (CDI) is influenced by the composition and metabolism of gut microbiota, which in turn are affected by diet. However, the mechanism underlying the interplay between d …
Only about 50% of patients with IBD respond to drugs...studies in Ireland looking at options for diet therapy #eaaciasn22 pic.twitter.com/YbBPVvusoj— Carina Venter PhD RD (@VenterCarina) September 11, 2022
Impact of Clostridioides Difficle Infection and its Therapy on Nutritional Status - PubMed
An interplay of various intrinsic and extrinsic factors such as systemic inflammation, diarrheal losses, and impact of isolation influence the nutritional status of patients with CDI. While diarrheal losses can lead to dehydration and electrolyte disturbances, isolation can further hamper adequate n …
Rewiring bugs: Diet, the gut microbiome, and nerve regeneration
Microbiome-to-nervous-system interactions are gaining much attention in fields that study health and disease, and diet is considered to be a key media…
AGA Clinical Practice Update on the Role of Diet in Irritable Bowel Syndrome: Expert Review - ScienceDirect
Irritable bowel syndrome (IBS) is a commonly diagnosed gastrointestinal disorder that can have a substantial impact on quality of life. Most patients …
This recent released systematic review on the absence of effects of the Mediterranean diet on gut microbiome highlights challenges of diet-microbiome studies. See this useful thread by @hmstaudacher: https://t.co/ZgKFVPVFfG— GutMicrobiota Health (@GMFHx) August 22, 2022
Effects of a low FODMAP diet on the colonic microbiome in irritable bowel syndrome: a systematic review with meta-analysis | The American Journal of Clinical Nutrition | Oxford Academic
ABSTRACTBackground. A low fermentable oligosaccharides, disaccharides, monosaccharides, and polyols (FODMAP) diet is increasingly used to manage symptoms in irr
Faecal microbiota transplantation with anti-inflammatory diet (FMT-AID) followed by anti-inflammatory diet alone is effective in inducing and maintaining remission over 1 year in mild to moderate ulcerative colitis: a randomised controlled trial | Gut
Objective Microbiome and dietary manipulation therapies are being explored for treating ulcerative colitis (UC). We aimed to examine the efficacy of multidonor faecal microbiota transplantation (FMT) and anti-inflammatory diet in inducing remission followed by long-term maintenance with anti-inflammatory diet in patients with mild-moderate UC. Design This open-labelled randomised controlled trial (RCT) randomised patients with mild-moderate (Simple Clinical Colitis Activity Index (SCCAI) 3–9) endoscopically active UC (Ulcerative Colitis Endoscopic Index of Severity (UCEIS)1) on stable baseline medications in 1:1 ratio to FMT and anti-inflammatory diet (FMT-AID) versus optimised standard medical therapy (SMT). The FMT-AID arm received seven weekly colonoscopic infusions of freshly prepared FMT from multiple rural donors(weeks 0–6) with anti-inflammatory diet. Baseline medications were optimised in the SMT arm. Clinical responders (decline in SCCAI3) at 8 weeks in both arms were followed until 48 weeks on baseline medications (with anti-inflammatory diet in the FMT-AID arm). Primary outcome measures were clinical response and deep remission (clinical—SCCAI
Nutritionist Shauna McQueen recognized the challenges of eating with C. diff when developing the lifestyle portion of our Nutrition Guide. Download your free copy here 👉 https://t.co/JI4OsFY4aD #idtwitter #cdiff #guthealth #microbiome pic.twitter.com/UBCr4cBH6E— Peggy Lillis Fund (@PeggyFund) August 5, 2022
The metabolic nature of inflammatory bowel diseases | Nature Reviews Gastroenterology & Hepatology
Nature Reviews Gastroenterology & Hepatology - Experimental and clinical evidence supports a role of metabolic perturbation in the development of gut inflammation in inflammatory bowel disease...
Go with your gut: scientist Tim Spector on why food is not just fuel | Human biology | The Guardian
The scientist has spent years studying how gut health relates not just to nutrition, but to all aspects of our everyday wellbeing. He explains why it really is what’s inside that counts
Functional bowel disorders with diarrhoea: Clinical guidelines of the United European Gastroenterology and European Society for Neurogastroenterology and Motility - Savarino - 2022 - United European Gastroenterology Journal - Wiley Online Library
Effects of dietary fibers, micronutrients, and phytonutrients on gut microbiome: a review | Applied Biological Chemistry | Full Text
The human gastrointestinal tract harbors a magnitude of bacteria, which are collectively known as the gut microbiome. Research has demonstrated that the gut microbiome significantly impacts the health of its host and alters the host’s risk for various chronic diseases. Many factors, such as diet, could potentially be manipulated to alter the host gut microbiome and induce subsequent preventative and/or therapeutic effects. It has been established that diet partakes in the regulation and maintenance of the gut microbiome; however, specific crosstalk between the microbiome, gut, and host has not been clearly elucidated in relation to diet. In this review of the scientific literature, we outline current knowledge of the differential effects of major plant-derived dietary constituents (fiber, phytochemicals, vitamins, and minerals) on the diversity and composition of the gut microbiome.
The gut microbiome: what every gastroenterologist needs to know
The mucosal surfaces of the body are characterised by complex, specialised microbial communities, often referred to as the microbiome . However, only much more recently—with the development of technologies allowing exploration of the composition and functionality of these communities—has meaningful research in this area become feasible. Over the past few years, there has been rapid growth in interest in the gut microbiome in particular, and its potential contribution to gastrointestinal and liver disease. This interest has already extended beyond clinicians to pharmaceutical companies, medical regulators and other stakeholders, and is high profile among patients and the lay public in general. Such expansion of knowledge holds the intriguing potential for translation into novel diagnostics and therapeutics; however, being such a nascent field, there remain many uncertainties, unanswered questions and areas of debate.
“Coming this summer is the Peggy Lillis Foundation Eating & Nutrition Guide, chock full of recipes and first hand information about eating while recovering from C. diff. Keep an eye out for it's launch 👀 #microbiome #guthealth #cdiff #cdifficile #amr #idtwitter”
A High-Carbohydrate Diet Prolongs Dysbiosis and Clostridioides difficile Carriage and Increases Delayed Mortality in a Hamster Model of Infection
Studies using mouse models of Clostridioides difficile infection (CDI) have demonstrated a variety of relationships between dietary macronutrients on antibiotic-associated CDI; however, few of these effects have been examined in more susceptible hamster models of CDI. In this study, we investigated …
Is it time to rethink healthy eating in light of the gut microbiome? This just released review explores how the contrasting effects of processed and whole plant foods on human health are, in part, mediated by the gut microbiome via @cellhostmicrobe https://t.co/oUvQinEBoo pic.twitter.com/LkVERmAp8g— GutMicrobiota Health (@GMFHx) June 15, 2022
Researchers are debating whether probiotics and microbiome-boosting foods can help our guts recover during periods of antibiotic use, allowing patients to stay on course with treatment.
Our host Anna Mohl speaks to Dr. Matt Henn, Ph.D, Chief Scientific Officer & Executive Vice President at Seres Therapeutics about understanding the microbiome. They’ll help us better understand how trillions of living organisms in our guts can affect everything from our digestion, to our mood, to how we fight off infections. Dr. Henn also talks about Seres’ work to develop what could potentially be the first approved pharmaceutical treatment based on the microbiome, and he gives us a glimpse of what’s on the horizon for innovations in the field.This podcast is hosted by Nestle Health Science. This podcast represents the opinions of host Anna and her guests on the show and do not reflect the opinion of Nestle Health Science. The content is for informational purposes only and should not be taken as medical advice, please consult your healthcare professional for any medical questions.