Found 9 bookmarks
Custom sorting
High-throughput screening identifies a novel natural product-inspired scaffold capable of inhibiting Clostridioides difficile in vitro
High-throughput screening identifies a novel natural product-inspired scaffold capable of inhibiting Clostridioides difficile in vitro
Clostridioides difficile is an enteric pathogen responsible for causing debilitating diarrhea, mostly in hospitalized patients. The bacterium exploits on microbial dysbiosis induced by the use of antibiotics to establish infection that ranges from mild watery diarrhea to pseudomembranous colitis. Th …
#vanco#fidax#test
·pubmed.ncbi.nlm.nih.gov·
High-throughput screening identifies a novel natural product-inspired scaffold capable of inhibiting Clostridioides difficile in vitro
Ferring and Rebiotix Present Landmark Phase 3 Data Demonstrating Superior Efficacy of Investigational RBX2660 Versus Placebo to Reduce Recurrence of C. difficile Infection - BioSpace
Ferring and Rebiotix Present Landmark Phase 3 Data Demonstrating Superior Efficacy of Investigational RBX2660 Versus Placebo to Reduce Recurrence of C. difficile Infection - BioSpace
Ferring and Rebiotix Present Landmark Phase 3 Data Demonstrating Superior Efficacy of Investigational RBX2660 Versus Placebo to Reduce Recurrence of C. difficile Infection
#vanco#fidax
·biospace.com·
Ferring and Rebiotix Present Landmark Phase 3 Data Demonstrating Superior Efficacy of Investigational RBX2660 Versus Placebo to Reduce Recurrence of C. difficile Infection - BioSpace
Microbome for c diff works
Microbome for c diff works
An investigational microbiome-based therapeutic for C difficile was found to exert continued efficacy 3 months after administration.
#vanco#fidax#test
·contagionlive.com·
Microbome for c diff works
In vivo efficacy of auranofin in a hamster model of Clostridioides difficile infection
In vivo efficacy of auranofin in a hamster model of Clostridioides difficile infection
Clostridioides difficile infections (CDIs) are an urgent public health threat worldwide and are a leading cause of morbidity and mortality in healthcare settings. The increasing incidence and severity of infections combined with the scarcity of effective anti-CDI agents has made treatment of CDI ver …
#vanco#fidax#test
·pubmed.ncbi.nlm.nih.gov·
In vivo efficacy of auranofin in a hamster model of Clostridioides difficile infection
Genome-based rational engineering of Actinoplanes deccanensis for improving fidaxomicin production and genetic stability
Genome-based rational engineering of Actinoplanes deccanensis for improving fidaxomicin production and genetic stability
Microbial fermentation is currently still the major way to produce structural complicated clinical drugs. Yet, the low productivity and genetic instability of producing strains remain the bottlenecks in microbial pharmaceutical industry. Fidaxomicin is a microbial drug against the Clostridium diffic …
#fidax
·pubmed.ncbi.nlm.nih.gov·
Genome-based rational engineering of Actinoplanes deccanensis for improving fidaxomicin production and genetic stability