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High-throughput screening identifies a novel natural product-inspired scaffold capable of inhibiting Clostridioides difficile in vitro
High-throughput screening identifies a novel natural product-inspired scaffold capable of inhibiting Clostridioides difficile in vitro
Clostridioides difficile is an enteric pathogen responsible for causing debilitating diarrhea, mostly in hospitalized patients. The bacterium exploits on microbial dysbiosis induced by the use of antibiotics to establish infection that ranges from mild watery diarrhea to pseudomembranous colitis. Th …
·pubmed.ncbi.nlm.nih.gov·
High-throughput screening identifies a novel natural product-inspired scaffold capable of inhibiting Clostridioides difficile in vitro
Ferring and Rebiotix Present Landmark Phase 3 Data Demonstrating Superior Efficacy of Investigational RBX2660 Versus Placebo to Reduce Recurrence of C. difficile Infection - BioSpace
Ferring and Rebiotix Present Landmark Phase 3 Data Demonstrating Superior Efficacy of Investigational RBX2660 Versus Placebo to Reduce Recurrence of C. difficile Infection - BioSpace
Ferring and Rebiotix Present Landmark Phase 3 Data Demonstrating Superior Efficacy of Investigational RBX2660 Versus Placebo to Reduce Recurrence of C. difficile Infection
·biospace.com·
Ferring and Rebiotix Present Landmark Phase 3 Data Demonstrating Superior Efficacy of Investigational RBX2660 Versus Placebo to Reduce Recurrence of C. difficile Infection - BioSpace
Microbome for c diff works
Microbome for c diff works
An investigational microbiome-based therapeutic for C difficile was found to exert continued efficacy 3 months after administration.
·contagionlive.com·
Microbome for c diff works
Seres Therapeutics to Present SER-109 Phase 3 Mechanistic Data at Keystone Symposium - BioSpace
Seres Therapeutics to Present SER-109 Phase 3 Mechanistic Data at Keystone Symposium - BioSpace
Seres Therapeutics, Inc. (Nasdaq: MCRB) announced today that it will present new data from its SER-109 Phase 3 ECOSPOR III clinical study that confirm the intended pharmacological properties of this investigational microbiome therapeutic for recurrent C. difficile infection (CDI).
·biospace.com·
Seres Therapeutics to Present SER-109 Phase 3 Mechanistic Data at Keystone Symposium - BioSpace
MGB Biopharma - Successful End-of-Phase 2 Meeting with FDA for MGB-BP-3 a Potential New Gold Standard First-Line Treatment for Clostridioides difficile Infection (CDI) - PRNewswire
MGB Biopharma - Successful End-of-Phase 2 Meeting with FDA for MGB-BP-3 a Potential New Gold Standard First-Line Treatment for Clostridioides difficile Infection (CDI) - PRNewswire
/PRNewswire/ -- MGB Biopharma, a biopharmaceutical company developing MGB-BP-3, a novel antibacterial, for the treatment of Clostridioides difficile (CDI),...
·prnewswire.com·
MGB Biopharma - Successful End-of-Phase 2 Meeting with FDA for MGB-BP-3 a Potential New Gold Standard First-Line Treatment for Clostridioides difficile Infection (CDI) - PRNewswire
In vivo efficacy of auranofin in a hamster model of Clostridioides difficile infection
In vivo efficacy of auranofin in a hamster model of Clostridioides difficile infection
Clostridioides difficile infections (CDIs) are an urgent public health threat worldwide and are a leading cause of morbidity and mortality in healthcare settings. The increasing incidence and severity of infections combined with the scarcity of effective anti-CDI agents has made treatment of CDI ver …
·pubmed.ncbi.nlm.nih.gov·
In vivo efficacy of auranofin in a hamster model of Clostridioides difficile infection