C Diff Drug Stewardship

Clindamycin oral capsule is a prescription medication that is used to treat bacterial infections. These infections include acne and bacterial vaginosis. Clindamycin oral capsule is available as a generic drug and as the brand-name drug Cleocin. Learn about its side effects, warnings, dosage, and more.

Proton pump inhibitors (PPIs) are the first-line treatment for many gastrointestinal conditions since their introduction in the 1980s.[i] They are amongst the top ten most widely used agents in...

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Implementation of a pharmacy-driven BLA reconciliation significantly increased β-lactam preoperative use without negative safety outcomes.

Cancer patients are more than twice as likely to acquire hospital-associated Staphylococcus aureus bacteraemia (HA-SAB) and Clostridioides difficile infection (HA-CDI) than others, a new study from Australia found.

No difference was observed in any of the outcomes and there was no impact on the duration of therapy.

Clostridioides difficile infection (CDI) has been an epidemic for many years. Our biggest challenge in treating CDI is preventing recurrence, which is seen in approximately 25% of patients with initial infection and in 40-60% of those with subsequent episodes. Given the major disease burden o …

Across 15 hospitals, there were differing opinions on the feasibility of implementing antibiotic restrictions for third/fourth-generation cephalosporins and fluoroquinolones. While the perceived barrier to implementing restrictions was frequently high, many hospitals were effectively using restricti …

New study paves the way for revaccination campaign in the autumn

Using piperacillin/tazobactam increases the risk for acute kidney injury, and this risk can be exacerbated by concurrent vancomycin.

The U.S. CDC and the European Centre for Disease Prevention and Control have identified antimicrobial resistance as an alarming global public health threat. The use of a host-response marker...

People who have faced debilitating side effects say we need better warnings on drugs. The FDA hasn’t been enthusiastic.

In addition to less antibiotic use, participating hospitals saw a 20% drop in hospital-onset C difficile.

In March, nearly 40 individuals from across the country will meet with their legislators to urge Congress to take bipartisan action to prioritize the battle against antibiotic resistance: a looming global health threat that threatens the future of modern medicine. As part of The Pew Charitable Trusts’ Stand Up to Superbugs initiative, this year’s ambassadors include health care professionals, public health officials, scientists, farmers and ranchers, veterinarians, superbug survivors, and people who have lost loved ones to an antibiotic-resistant infection. They will meet virtually with fed...

Dr David Johnson comments on new data indicating that it may be time to move away from metronidazole plus a fluoroquinolone in certain patients.

The findings should assuage concerns about small intestinal bacterial overgrowth when prescribing treatment with proton pump inhibitors.

Older adult patients who received antibiotic prophylaxis for UTIs experienced an increased risk for hospitalization, sepsis and bloodstream infection, according to a study in Clinical Infectious Diseases.“Older patients have a higher risk of infection than younger patients due in large part to immunosenescence, but at the same time they are more prone to the harms of antibiotics such as

Exposure to PPIs was associated with a moderate increase in the risk of community-acquired C diff infection, even after treatment discontinuation.

According to one new study, proton-pump inhibitors (PPI) exposure demonstrated a moderate increase in the risk of community-acquired C diff infection.

Researchers found 8 meta-analysis and systematic reviews showing the positive link between PPI use and the risk of clostridium difficile infections.

A quality improvement program reduced antibiotic use and strengthened antimicrobial stewardship in hospitals, according to an analysis published in JAMA Network Open. Pranita D. Tamma, MD, MHS, associate professor of pediatrics and director of the pediatric antimicrobial stewardship program at Johns Hopkins Medicine, and colleagues evaluated the effectiveness of the Agency for Healthcare

According to the Centers for Disease Control and Prevention, at least 2.8 million antibiotic-resistant infections occur each year, killing at least 35,000 people. All antibiotic use contributes to resistance. To slow the rise of this growing public health threat, antibiotics should be used only when needed and when prescribed appropriately: the proper drug at the correct dose for the right duration.

Article in April 2021 issue of The Joint Commission Journal on Quality and Patient Safety...

There is a growing interest in the potentially deleterious impact of antibiotics on gut microbiota. Patients with bone and joint infection (BJI) require prolonged treatment that may impact significantly the gut microbiota. We collected samples from patients with BJI at baseline, end of antibiotics ( …