The use of OVP significantly reduced the incidence of CDI during the in-hospital ASCT course without increasing CDI post-OVP use. These encouraging results should promote further research into the use of OVP in ASCT.

Oral Vancomycin to Prevent Clostridioides difficile in Stem Cell Transplant Recipients: The Last Frontier in Antimicrobial Prophylaxis

Background: Systematic surveillance of Clostridioides difficile infection (CDI) in our institution showed a reduction in the incidence of healthcare associated CDI (HA-CDI) during COVID-19 pandemic. Aim: Our objective was to search for factors related to this reduction. Metho …

CDC - Blogs - Safe Healthcare Blog – I am a C. diff survivor. What I know now and what I want others to know. - The Division of Healthcare Quality Promotion plans to blog on as many healthcare safety topics as possible. We encourage your participation in our discussion and look forward to an active exchange of ideas.

Multivalent vaccine tackles C. difficile

Jose Alexander, MD, offers some insights on the antimicrobial and its activity against various gram-negative pathogens such as pseudomonas, enterobacterales.

Infection preventionists face severe stress from prolonged crisis-mode work environments, highlighting the need for boundaries, support, and self-compassion to restore personal well-being.

In some cases, yes, but there’s still much that experts have yet to learn about how these microscopic organisms work.

The STOP-CDI intervention presented by Matthew J.Ziegler, MD MSCE revealed using prophylactic enteral vancomycin, significantly reduced hospital-onset C difficile infections among immunocompromised patients.

A useful US study has explored the ratio between infection prevention staffing levels, facility size, and HCAI-related outcomes. The reassuring news is that there was some correlation between IPC s…

Peggy Lillis Foundation CEO Christian Lillis believes patients need a seat at the table so he is advocating for past patients to become ambassadors to be a voice to help shape treatment and also continue to raise awareness about the infection.

Background: The relative importance of different ultraviolet-C (UV-C) emitter configurations on the attenuation of vegetative bacterial and fungal pathogens has not been assessed. We hypothesize...

This novel approach allows facilities to staff their IPC program based on individual factors. Future versions of the calculator will be optimized based on the findings. Future research will clarify the impact of staffing on patient outcomes and staff retention.

In this exclusive article, Devin Jopp, the CEO of APIC, discusses the upcoming day-long virtual conference entitled “APIC AI Summit: The Impact of AI on IPC.”

A study by Loveleen Tina Joshi, PhD raised concerns about bleach-resistant C difficile strains, and Curtis J. Donskey, MD, and his team answered.

YARDLEY, PA — Groundbreaking research published in the Journal of Occupational and Environmental Hygiene reveals a 99.98% reduction in harmful toilet plume aerosols (TPAs) using the Splashblocker toilet cover. This innovative …

Background: The impact of ultraviolet-C (UV-C) emitter configuration on pathogen attenuation has not been assessed. We hypothesized that emitter configuration would impact UV-C efficacy for Clos...

More commonly known as C. diff, Clostridioides difficile is a microbe known to cause diarrhoea, colitis and other bowel complications

The far UV-C light technology could potentially be useful for automated decontamination of air and surfaces in bathrooms in healthcare and community settings.

Maryann Webb’s harrowing, personal experience with C diff, along with her professional work with federal agencies has prepared her for a life in advocacy with the Peggy Lillis Foundation. She wants to see the fecal microbiota transplant become more accessible and is working with Congress to make the infection a notifiable infectious disease.

Data for action: the crucial role of hospitals in controlling Clostridioides difficile infection in England

Despite heightened epidemiological surveillance, Clostridioides difficile continues to be associated with high rates of morbidity and mortality worldwide.1 The pathogen imposes a severe burden on health-care resources, as recurrences of C difficile infection (CDI) are estimated to occur in up to 25% of treated patients,2 and these recurrences increase with each subsequent episode, such that 40–65% of patients experience multiple recurrences after a second or third episode respectively.2 Changes in C difficile epidemiology introduce new complexities such as the emergence of the hypervirulent ribotype 027 and other ribotypes, which show inherent differences in genetic profiles, virulence factors, geographical distribution, and antimicrobial susceptibility profiles.

Our study supports previous reports of non-inferiority of allo-HSCT without use of antibiotic prophylaxis with close monitoring and rapid intervention, if infection is suspected. The trend towards improved outcomes without antibiotic prophylaxis, however, might not only be due to the absence of anti …

Sean Brown’s 2024 Disease Prevention Summit presentation emphasized leveraging technology, prioritizing high-risk patients, and environmental surveillance to enhance infection prevention and control strategies.

For the first time in the organization's history, all of the honourees are women. Each honouree is dedicated to creating positive change in the fight against ‘C. diff’.

Hospital-acquired pneumonia (HAP) is a significant infection prevention concern, leading to high patient mortality, increased health care costs, and ICU usage. Oral hygiene is an effective preventive measure.

Take 5 minutes to catch up on Infection Control Today’s highlights for the week ending September 6, 2024.

This new column, Clean Hospital with Alexandra Peters, PhD, explores advancements in health care environmental hygiene, highlighting its growing recognition as a key component of infection prevention and honoring pioneers like Professor Stephanie Dancer.

Discover Tamara Behm's journey in seeking an IP leadership role, her passion for patient safety, and advice for job-seeking professionals in infection prevention, in this discussion with ICT’s IPLifeline.