C Diff Prevention

Any decrease in the devastation of Clostridioides difficile is welcomed, but an investigative team brought the numbers down by 50%. See what control measures they used.

Attendees at the Society for Healthcare Epidemiology of America (SHEA) 2023 Spring Conference heard presentations about using electronic health records to identify cases of Clostridioides difficile earlier, as well as an update about infection control strategies.

Hydrogen peroxide-peroxyacetic acid-based, disinfectant has a 5-minute contact time for efficacy against Cdiff spores and less for most other bacteria and viruses. The reduction in #CDIFF cases is impresive#yearininfectioncontrol #IDTwitter #ECCMID2023 @infectoHU @ameinac pic.twitter.com/8Z0Cxhvf8t— Adrian Camacho-Ortiz (@infecto79) April 15, 2023

The epidemiology society worked with a few medical organizations to update the guidance to limit infections.

2 CDI recurrences occurred in this study, both in placebo recipients who were immunocompromised.

Probiotics have shown great promise in promoting human health. Despite the promising evidence, there is little information on the clinical efficacy of…

Strategies to prevent Clostridioides difficile infections in acute-care hospitals: 2022 Update

If hospitals want to prevent Clostridium difficile infections, it's essential they adopt antimicrobial stewardship programs, according to updated guidance from five medical organizations.

SHEA-IDSA-APIC-American-Hospital-Association-and-The-Joint-Commission-have-updated-their-practice-recommendations-concerning-strategies-to-prevent-HAIs-through

Investigators reviewed the current literature on the utility of oral vancomycin prophylaxis (OVP), and offered guidance for when this approach may be beneficial.

There were few or no studies investigating education and training, personal protective equipment or monitoring, and evaluation of interventions.

This study represents the first multiple-site, quasi-experimental study with control hospitals and a nonequivalent dependent variable to evaluate a 4-component intervention on HO-CDI. Following ongoing improvement in cleaning thoroughness, there was a sustained 50% decrease in HO-CDI SIRs compared t …

Each year, about 500,000 people in the U.S. deal with gastrointestinal infections from Clostridioides difficile (C. diff), and more than 20,000 die from these infections. A new study performed in mice ...

Take 5 minutes to catch up on Infection Control Today’s highlights for the week ending November 18, 2022.

Faster, Even Easier to Use --- and 99.99% Inactivation of Candida auris and C.difficile Spores This week at the Association for Perioperative Registered Nurses (AORN) Global Surgical Conference and Expo 2023,

Background Probiotics have been deemed multipotent and unprecedentedly applied in the health field recently. However, there are challenges in promoting credible and reliable resources while avoiding misinformation regarding probiotics for the public. Methods This study analysed 400 eligible probiotic-related videos selected from YouTube, and the three most popular video-sharing platforms (Bilibili, Weibo and TikTok) in China. Video retrieval was performed on September 5th, 2022. GQS and tailored DISCERN tool assess each video’s quality, usage, and reliability. A comparative analysis of videos from different sources was carried out. Results The identity distribution of probiotic video-producers was predominantly experts (n = 202, 50.50%), followed by amateurs (n = 161, 40.25%) and health-related institutions (n = 37, 9.25%). The videos’ content category mainly discussed the function of probiotics (n = 120, 30%), the way to choose suitable products (n = 81, 20.25%), and the methods for taking probiotics (n = 71, 17.75%).The overall quality of videos was moderate (3/5 point) assessed by GQS, while the usage (1/6 point) and reliability (2/5 point) detailing probiotics assessed by tailored DISCERN tool were poor. The attitude of probiotic video-producers was primarily positive (n = 323, 80.75%), followed by neutral (n = 52, 13.00%) and negative (n = 25, 6.25%) (P

A work system analysis using SEIPS identified barriers and facilitators to CDI prevention practices that could be addressed both nationally at the system level and locally at the facility level, specifically in the areas of communication and coordination.

Probiotics are used for both generally healthy consumers and in clinical settings. However, theoretical and proven adverse events from probiotic consumption exist. New probiotic strains and product...

A new study identified a compound that prevents C. diff infection. Researchers are now using this compound to develop new drug candidates that might eventually

Scientific Reports - Dose optimization in surgical prophylaxis: sub-inhibitory dosing of vancomycin increases rates of biofilm formation and the rates of surgical site infection

Clostridioides difficile infection (CDI) is a serious disease with a high recurrence rate. The single and mixed biofilms formed by C. difficile in the gut contribute to the formation of recurrent CDI (rCDI). In parallel, other gut microbes influence the formation and development of …

AbstractAims. Clostridioides difficile infections (CDI) are a major cause of morbidity and mortality in hospitalized patients. A probiotic formulation (Bio-K+)

👀 According to the HHS over 2 million U.S patients will suffer with healthcare-associated infections (HAIs) this year, over 90,000 of them will die. 👀https://t.co/5vMlma6YtM#technology #infectionprevention #innovation #mrsa #cdiff #hai #hospital #healthcare pic.twitter.com/XhCqaiRu7e— UV222™ (@uv222health) March 15, 2023

Artificial intelligence could be a game changer as scientists work to combat the growing threat of antibiotic resistance.

With antibiotic resistance on the rise, new solutions are needed to fight superbugs.

The lactobacilli tested could have a role in the motility, the quorum sensing (QS), the survival of the spores and the germination potential of the spores, which are essential elements for the virulence of C. difficile.

Where are we on the role of probiotics in IBS and IBD?.@soda_xl, Quigley & @ProfWhelan offer a quick overview in the field: small effects sizes seen in IBS and efficacy for ulcerative colitis remissionhttps://t.co/jIwXvEwNvd— GutMicrobiota Health (@GMFHx) March 13, 2023

Institutions with active BMT units should consider implementing ADI.

A recent study reveals that probiotics are not equally effective in preventing Clostridioides difficile (C. diff.) colonization. The research highlights a