C Diff Prevention

When you’re a patient, which room or bed you’re put in largely determines your risk of getting infected.

Healthcare-associated infections (HCAIs) are a major challenge and the near patient surface is important in harbouring causes such as methicillin-resistant Staphylococcus aureus (MRSA) and Clostridioides difficile. Current approaches to decontamination are sub-optimal and many studies …

The push to heed warning from public health experts faces buzzsaw of end-of-year budgeting.

Probiotics can alter brain function via the gut–brain axis. We investigated the effect of a probiotic mixture containing Bifidobacterium longum, Lactobacillus helveticus and Lactiplantibacillus plantarum. In a randomized, placebo-controlled, double-blinded crossover design, 22 healthy subjects (6 m/16 f; 24.2 ± 3.4 years) underwent four-week intervention periods with probiotics and placebo, separated by a four-week washout period. Voxel-based morphometry indicated that the probiotic intervention affected the gray matter volume of a cluster covering the left supramarginal gyrus and superior parietal lobule (p 0.0001), two regions that were also among those with an altered resting state functional connectivity. Probiotic intervention resulted in significant (FDR 0.05) functional connectivity changes between regions within the default mode, salience, frontoparietal as well as the language network and several regions located outside these networks. Psychological symptoms trended towards improvement after probiotic intervention, i.e., the total score of the Hospital Anxiety and Depression Scale (p = 0.056) and its depression sub-score (p = 0.093), as well as sleep patterns (p = 0.058). The probiotic intervention evoked distinct changes in brain morphology and resting state brain function alongside slight improvements of psycho(bio)logical markers of the gut–brain axis. The combination of those parameters may provide new insights into the modes of action by which gut microbiota can affect gut–brain communication and hence brain function.

Research on the susceptibility of the spores of anaerobic bacteria such as Clostridium sporogenes or Clostridioides difficile is vital for assessing the sporicidal activity of disinfectants. The diverse susceptibility of anaerobic bacteria spores may lead to different disinfection para …

Find out what is known about the anti-inflammatory effects of probiotics and their potential applications at the bedside.

Drs. Lodise and Feuerstadt discuss educational opportunities to combat and reduce C. difficile infection (CDI).

1. In a randomized control trial, administration of multispecies probiotics did not affect the incidence of antibiotic-associated diarrhea as defined by strict criteria. 2. Multispecies probiotic use was associated with a decreased risk of developing diarrhea regardless of etiology and of requiring intravenous rehydration due to diarrhea. Evidence Rating Level: 1 (Excellent) Study Rundown: Antibiotic-associated diarrhea

Clostridioides difficile infection is closely related to the intestinal flora disorders induced by antibiotics, and changes in the intestinal flora may cause the occurrence and development of Clostridioides difficile infection. Epigallocatechin-3-gallate (EGCG) is one of the major bioa …

We provide a status report of the IPC characteristics and practices Israeli hospitals are currently using to prevent HAIs during the COVID-19 era. While many globally accepted IPC practices are widely implemented, opportunities to increase the use of certain IPC practices in Israeli hospitals exist.

Postbiotics and next-generation probiotics are emerging strategies to promote health and manage disease through targeting the human microbiome in a specific way. This article updates what is known in the field.

The GI infection is increasingly common but little known

Clostridioides difficile infection following ileostomy reversal - can we clean up our act?

Simply adding an admission screening question and a 2-step testing algorithm sharply decreased the number of Clostridioides difficile infections (CDI) in the year after implementing the interventions.

The number of incident CDI cases can be dramatically decreased by implementing an admission screening question and a 2-step testing algorithm.

[vc_row][vc_column width=”1/4″][vc_single_image image=”447″ img_size=”full” alignment=”center”][/vc_column][vc_column width=”3/4″][vc_column_text] Background The use of hydrogen peroxide vapour (HPV) decontamination and the impact on rates of clostridium difficile was evaluated.[/vc_column_text][/vc_column][/vc_row][vc_row][vc_column][vc_separator color=”custom” accent_color=”#d7d8e0″][/vc_column][/vc_row][vc_row][vc_column width=”1/4″][vc_single_image image=”449″ img_size=”full” alignment=”center”][/vc_column][vc_column width=”3/4″][vc_column_text] Method Calderdale and Huddersfield NHS Foundation Trust incorporated Inivos’ HPV disinfection robot into their cleaning routine, introduced a RAG-rated cleaning system and measured. […]

Petrosillo: Routine administration of probiotics and anti-CDI antibiotics are not recommended for prevention of CDI @esnm_eu #GMFHCoverage pic.twitter.com/VgYhrA68kF— GutMicrobiota Health (@GMFHx) September 6, 2022

S. boulardii administration is associated with a significant HO-CDI risk reduction for inpatients receiving antibiotics associated with CDI. Institutions interested in targeted use of S. boulardii to limit potential adverse effects may consider prophylaxis for inpatients with pneumonia or receiving …

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Drs. Lodise and Feuerstadt discuss educational opportunities to combat and reduce C. difficile infection (CDI).

Drs. Lodise and Feuerstadt discuss educational opportunities to combat and reduce C. difficile infection (CDI).

Delta Hospital has two robots, which look vaguely like R2D2 from the movie Star Wars.

There are many different probiotic products on the market. Are they all equally effective? What criteria should a probiotic formulation meet to provide the most benefit to the patient? The current research aims to evaluate the parameters that influence the effectiveness of market probiotic products. …

The COVID-19 pandemic has required novel solutions, including heat disinfection of personal protective equipment (PPE) for potential reuse to ensure availability for healthcare and other frontline workers. Understanding the efficacy of such methods on pathogens other than SARS-CoV-2 that may be pres …

Clostridiodes difficile continues to be a significant cause of healthcare-associated infections, leading to increased length of stay and healthcare costs.

EvaClean, the infection prevention division of EarthSafe Chemical Alternatives, says the efficacy of its PurTabs disinfectant has been confirmed in ..

Programs seeking to implement advances in health care epidemiology must critically evaluate their impact on infection prevention processes, patient safety, and cost prior to wholesale adoption.