Effectiveness of ozone generated by a dielectric barrier discharge plasma reactor against multidrug-resistant pathogens and Clostridioides difficile spores
The contaminated healthcare environment plays an important role in the spread of multidrug-resistant organisms (MDROs) and Clostridioides difficile. This study aimed to evaluate the antimicrobial effects of ozone generated by a dielectric barrier discharge (DBD) plasma reactor on various materials t …
Effectiveness of ozone generated by a dielectric barrier discharge plasma reactor against multidrug-resistant pathogens and Clostridioides difficile spores
Scientific Reports - Effectiveness of ozone generated by a dielectric barrier discharge plasma reactor against multidrug-resistant pathogens and Clostridioides difficile spores
Survival of Clostridioides difficile spores in thermal and chemo-thermal laundering processes and influence of the exosporium on their adherence to cotton bed sheets - PubMed
Clostridioides difficile spores were previously demonstrated to survive industrial laundering. Understanding interactions between heat, disinfectants and soiling (e.g. bodily fluids) affecting C. difficile spore survival could inform the optimization of healthcare laundry processes. Reducing spore a …
The Efficacy of the BioFire FilmArray Gastrointestinal Panel to Reduce Hospital Costs Associated With Contact Isolation: A Pragmatic Randomized Controlled Trial - Cureus
Background: Molecular syndromic panels can rapidly detect common pathogens responsible for acute gastroenteritis in hospitalized patients. Their impact on both patient and healthcare system outc...
C. Diff is a nasty bacteria that causes diarrhea and colitis. 1:11 people over 65 diagnosed with a C. Diff infection die within a month.222nm UV light delivers significantly better inactivation results than 254nm, is cheaper and is safe for use in occupied spaces!#cdiff #hai pic.twitter.com/ruRpmeJHzf— UV222™ (@uv222health) August 12, 2022
Antagonistic activity of selenium-enriched Bifidobacterium breve against Clostridioides difficile
Probiotics have the potential to be used in the prevention of Clostridioides difficile infection (CDI). In this study, selenium (Se)-enriched Bifidobacterium breve YH68-Se was obtained under optimal culture conditions with single-factor and response surface optimization. The overall environmental re …
Online information in Spanish on probiotics, yoghurt, kefir, kombucha, fibre and prebiotics: an analysis of the quality of information and the certainty of the evidence supporting health claims | BMJ Open
Objective To examine the certainty of the evidence supporting health claims about probiotics, yoghurt, kefir, kombucha, fibre and prebiotics, and to assess the quality of online information in Spanish. Design Content analysis. Methods We compiled a data set of 114 web pages by searching six popular search phrases in Spanish relating to probiotics, yoghurt, kefir, kombucha, fibre and prebiotics on Google.es and coded them for typology and health claims. We examined the certainty of the evidence for health claims from systematic reviews. Information quality was assessed according to 10 criteria, where a web page: mentions scientific publications and reports their conclusions; quantifies relative and absolute effects; acknowledges some limitations; discusses certainty of evidence; reports the potential harms, alternatives and costs; and does not argue based on personal experiences. Results Gastrointestinal health (86.0%), general health (57.9%), cardiovascular health (53.5%) and immune system health (50.9%) were the most widely mentioned topics. Half of claims (52.6%, 70/133) were supported by evidence from systematic reviews. Probiotics had the highest number of claims supported by evidence and kombucha the lowest. The highest certainty was found for antibiotic-associated diarrhoea, necrotising enterocolitis and otitis (moderate) in probiotics and yoghurt, infectious diarrhoea and hepatic encephalopathy (moderate) in prebiotics, and cardiovascular health (high to moderate) and colorectal cancer (moderate) in fibre. On a scale of 0–10, the median information quality score for all web pages was 3. Only 18.4% reported study conclusions, 7.9% quantified the effects, 28.9% acknowledged some limitations in the research and 42.1% reported potential harms. Conclusions Most online health claims for dietary interventions intended for improving health through the gut microbiome are supported by low or very low certainty of evidence. Online information does not align with the evidence and is incomplete or unbalanced. All data relevant to the study are included in a public, open access repository. The data set is available on the following: [https://figshare.com/articles/journal\_contribution/Supplemental\_material_1/20203415][1], [https://figshare.com/articles/journal\_contribution/Table\_S2/19425824][2], [https://figshare.com/articles/journal\_contribution/Supplemental\_material_3/20204021][3], [https://figshare.com/articles/journal\_contribution/Supplemental\_material_4/20204270][4]. [1]: https://figshare.com/articles/journal_contribution/Supplemental_material_1/20203415 [2]: https://figshare.com/articles/journal_contribution/Table_S2/19425824 [3]: https://figshare.com/articles/journal_contribution/Supplemental_material_3/20204021 [4]: https://figshare.com/articles/journal_contribution/Supplemental_material_4/20204270
Selecting the Best Disinfectant/Application Method: Keeping C difficile and C auris at Bay - Infection Control Today
A recent study by NYU Langone investigators determined that disinfecting high-touch surfaces within patient rooms with NaDCC via wipes and electrostatic sprayers yielded lower mean bacteria colony counts.
Appropriate cleaning reduces potential risk of spore transmission from patients with Clostridioides difficile infection treated in outpatient infusion centers
Environmental C. difficile contamination was increased after CDI infusions and significantly reduced after cleaning with a hypochlorite solution, reducing the potential risk of spore transmission to others.
Do Probiotics Prevent Clostridium difficile-Associated Diarrhea? - Cureus
Clostridium difficile is a bacterium that affects the gastrointestinal tract and is the leading cause of antibiotic-associated diarrhea. A wide range of probiotics has been studied and used to p...
The Role of Health Care Laundry in Infection Prevention - Infection Control Today
Environmental sources of pathogen organisms can sometimes be difficult to narrow down in a health care facility. One possible source of transmission is the laundry used, and not maintaining strict cleanliness attention can put both patients and workers at risk.
Preventing C. diff in and out of the hospital - Harvard Health
The bacteria C. diff is responsible for half a million infections each year in the US. Many infections happen when people are hospitalized, but a recent report indicated that people can be i...
Multispecies probiotic reduces overall risk of diarrhea in antibiotic-treated children - 2 Minute Medicine
1. In a small randomized controlled trial, administration of a multispecies probiotic during antibiotic therapy and for 7 days afterwards significantly reduced risk of diarrhea from all causes compared to placebo. 2. Probiotic administration did not affect risk of antibiotic-associated diarrhea (AAD), defined as diarrhea either caused by C. difficile or without another identified pathogenic
Impact of Hospital Environmental Cleaning with a Potassium Peroxymonosulphate-Based Environmental Disinfectant and Antimicrobial Stewardship on the Reduction of Hospital-Onset Clostridioides difficile Infections
We revealed that DOT of carbapenems and use of PPED were associated with the HO-CDI ratio and that both interventions reduced the rate of HO-CDI. This is the first report on the impact of hospital ward cleaning with PPED on the reduction of HO-CDI.
Terminal Cleaning, Including UV Sterilization, Effectiveness in Mitigating Pathogen Transmission - Infection Control Today
For terminal cleans, investigators studied the effect of UV-C disinfection added to chlorine-based disinfectants on the likelihood of source occupant MDRO transmission to subsequent exposed occupants.
The Best Cleaning Methods for C. difficile/C. auris #cleaning #Cdiff #Cauris #hospitals #disinfectant
The Best Cleaning Methods for C. difficile/C. auris#cleaning #Cdiff #Cauris #hospitals #disinfectant https://t.co/qbgIJeaJL2— Environmental Center (@greendailynews) July 12, 2022
Live Biotherapeutic Product (LBP) Market worth $ 2.60 billion by 2030 - Exclusive Report by InsightAce Analytic - Yahoo Finance
InsightAce Analytic Pvt. Ltd. has announced the publication of a market research report titled "Global Live Biotherapeutic Product (LBP) Market (By Type of Product(Probiotic drugs, Other drugs), By Type of Molecule(Small molecules, Biologics), By Target disease indication(Graft Versus Host Disease, Necrotizing Enterocolitis, Primary Hyperoxaluria, Recurrent C. difficile Infection, Others), By Therapeutic area (Digestive and Gastrointestinal Disorders, Infectious Diseases, Rare Disorders, Others)
Mobile phones of paediatric hospital staff are never cleaned and commonly used in toilets with implications for healthcare nosocomial diseases
Scientific Reports - Mobile phones of paediatric hospital staff are never cleaned and commonly used in toilets with implications for healthcare nosocomial diseases
Selecting the Best Disinfectant/Application Method: Keeping C difficile and C auris at Bay
A recent study by NYU Langone investigators determined that disinfecting high-touch surfaces within patient rooms with NaDCC via wipes and electrostatic sprayers yielded lower mean bacteria colony counts.
Engineering probiotics to inhibit Clostridioides difficile infection by dynamic regulation of intestinal metabolism - PubMed
Clostridioides difficile infection (CDI) results in significant morbidity and mortality in hospitalised patients. The pathogenesis of CDI is intrinsically related to the ability of C. difficile to shuffle between active vegetative cells and dormant endospores through the processes of germination and …
The impact of universal glove and gown use on Clostridioides difficile acquisition, a cluster randomized trial
Glove and gown use for all patient contact in medical and surgical ICUs did not result in a reduction in the acquisition of C. difficile compared with usual care.