C Diff Prevention

Gene-edited probiotics combat C. difficile in gut

C. Diff is a nasty bacteria that causes diarrhea and colitis. 1:11 people over 65 diagnosed with a C. Diff infection die within a month.222nm UV light delivers significantly better inactivation results than 254nm, is cheaper and is safe for use in occupied spaces!#cdiff #hai pic.twitter.com/ruRpmeJHzf— UV222™ (@uv222health) August 12, 2022

Probiotics have the potential to be used in the prevention of Clostridioides difficile infection (CDI). In this study, selenium (Se)-enriched Bifidobacterium breve YH68-Se was obtained under optimal culture conditions with single-factor and response surface optimization. The overall environmental re …

The product – Pathisol – can disinfect a surface in two minutes, which is five times faster than bleach.

Objective To examine the certainty of the evidence supporting health claims about probiotics, yoghurt, kefir, kombucha, fibre and prebiotics, and to assess the quality of online information in Spanish. Design Content analysis. Methods We compiled a data set of 114 web pages by searching six popular search phrases in Spanish relating to probiotics, yoghurt, kefir, kombucha, fibre and prebiotics on Google.es and coded them for typology and health claims. We examined the certainty of the evidence for health claims from systematic reviews. Information quality was assessed according to 10 criteria, where a web page: mentions scientific publications and reports their conclusions; quantifies relative and absolute effects; acknowledges some limitations; discusses certainty of evidence; reports the potential harms, alternatives and costs; and does not argue based on personal experiences. Results Gastrointestinal health (86.0%), general health (57.9%), cardiovascular health (53.5%) and immune system health (50.9%) were the most widely mentioned topics. Half of claims (52.6%, 70/133) were supported by evidence from systematic reviews. Probiotics had the highest number of claims supported by evidence and kombucha the lowest. The highest certainty was found for antibiotic-associated diarrhoea, necrotising enterocolitis and otitis (moderate) in probiotics and yoghurt, infectious diarrhoea and hepatic encephalopathy (moderate) in prebiotics, and cardiovascular health (high to moderate) and colorectal cancer (moderate) in fibre. On a scale of 0–10, the median information quality score for all web pages was 3. Only 18.4% reported study conclusions, 7.9% quantified the effects, 28.9% acknowledged some limitations in the research and 42.1% reported potential harms. Conclusions Most online health claims for dietary interventions intended for improving health through the gut microbiome are supported by low or very low certainty of evidence. Online information does not align with the evidence and is incomplete or unbalanced. All data relevant to the study are included in a public, open access repository. The data set is available on the following: [https://figshare.com/articles/journal\_contribution/Supplemental\_material_1/20203415][1], [https://figshare.com/articles/journal\_contribution/Table\_S2/19425824][2], [https://figshare.com/articles/journal\_contribution/Supplemental\_material_3/20204021][3], [https://figshare.com/articles/journal\_contribution/Supplemental\_material_4/20204270][4]. [1]: https://figshare.com/articles/journal_contribution/Supplemental_material_1/20203415 [2]: https://figshare.com/articles/journal_contribution/Table_S2/19425824 [3]: https://figshare.com/articles/journal_contribution/Supplemental_material_3/20204021 [4]: https://figshare.com/articles/journal_contribution/Supplemental_material_4/20204270

A recent study by NYU Langone investigators determined that disinfecting high-touch surfaces within patient rooms with NaDCC via wipes and electrostatic sprayers yielded lower mean bacteria colony counts.

Environmental C. difficile contamination was increased after CDI infusions and significantly reduced after cleaning with a hypochlorite solution, reducing the potential risk of spore transmission to others.

The easing of capacity restrictions in Quebec institutions comes as many long-term care homes are grappling with new COVID-19 outbreaks.

Clostridium difficile is a bacterium that affects the gastrointestinal tract and is the leading cause of antibiotic-associated diarrhea. A wide range of probiotics has been studied and used to p...

C. diff and C. auris are found on hospital beds, surfaces, and floors. New disinfectant applications may be the key to controlling these germs

Aged care industry news Australia

Infections at community hospitals fell by 63% after 1 year and 77% after 3 years, new data show.

Environmental sources of pathogen organisms can sometimes be difficult to narrow down in a health care facility. One possible source of transmission is the laundry used, and not maintaining strict cleanliness attention can put both patients and workers at risk.

The bacteria C. diff is responsible for half a million infections each year in the US. Many infections happen when people are hospitalized, but a recent report indicated that people can be i...

1. In a small randomized controlled trial, administration of a multispecies probiotic during antibiotic therapy and for 7 days afterwards significantly reduced risk of diarrhea from all causes compared to placebo. 2. Probiotic administration did not affect risk of antibiotic-associated diarrhea (AAD), defined as diarrhea either caused by C. difficile or without another identified pathogenic

We revealed that DOT of carbapenems and use of PPED were associated with the HO-CDI ratio and that both interventions reduced the rate of HO-CDI. This is the first report on the impact of hospital ward cleaning with PPED on the reduction of HO-CDI.

For terminal cleans, investigators studied the effect of UV-C disinfection added to chlorine-based disinfectants on the likelihood of source occupant MDRO transmission to subsequent exposed occupants.

The Best Cleaning Methods for C. difficile/C. auris#cleaning #Cdiff #Cauris #hospitals #disinfectant https://t.co/qbgIJeaJL2— Environmental Center (@greendailynews) July 12, 2022

InsightAce Analytic Pvt. Ltd. has announced the publication of a market research report titled "Global Live Biotherapeutic Product (LBP) Market (By Type of Product(Probiotic drugs, Other drugs), By Type of Molecule(Small molecules, Biologics), By Target disease indication(Graft Versus Host Disease, Necrotizing Enterocolitis, Primary Hyperoxaluria, Recurrent C. difficile Infection, Others), By Therapeutic area (Digestive and Gastrointestinal Disorders, Infectious Diseases, Rare Disorders, Others)

Scientific Reports - Mobile phones of paediatric hospital staff are never cleaned and commonly used in toilets with implications for healthcare nosocomial diseases

A recent study by NYU Langone investigators determined that disinfecting high-touch surfaces within patient rooms with NaDCC via wipes and electrostatic sprayers yielded lower mean bacteria colony counts.

Clostridioides difficile infection (CDI) results in significant morbidity and mortality in hospitalised patients. The pathogenesis of CDI is intrinsically related to the ability of C. difficile to shuffle between active vegetative cells and dormant endospores through the processes of germination and …

抗生素相关性腹泻是使用抗菌药物后出现的常见不良反应，与继发性肠道菌群紊乱所致肠道碳水化合物和胆汁酸代谢降低及条件致病菌感染等机制相关，儿童尤其是婴幼儿和危重症住院患儿是高危人群。本文着重介绍抗生素相关性腹泻的诊断、预防和治疗的相关知识，有助于儿科医师提高对本病的认知和防治水平。.

Glove and gown use for all patient contact in medical and surgical ICUs did not result in a reduction in the acquisition of C. difficile compared with usual care.

The use of NaDCC for surface disinfection resulted in the lowest bacterial colony counts on patient room high touch surfaces in our study.

Cohorting of patients with CDI is used to prevent cross-transmission, though it raises a major concern regarding quality of care. In this study we show there was no compromise in patient care, therefore it is a reasonable component of an enhanced infection control strategy in a hospital setting.

Clostridioides difficile is responsible for post-antibiotic diarrhea and most of the pseudomembranous colitis cases. Multiple recurrences, one of the major challenges faced in C. difficile infection (CDI) management, can be considered as chronic infections, and the role of biofilm form …

An environmental hygiene program meant to improve cleaning thoroughness led to a sustained 50% decrease in health care-onset Clostridioides difficile infection in eight hospitals, a study found.

Clostridioides difficile is responsible for post-antibiotic diarrhea and most of the pseudomembranous colitis cases. Multiple recurrences, one of the major challenges faced in C. difficile infection (CDI) management, can be considered as chronic infections, and the role of biofilm form …