C Diff Prevention

The deadly superbug, Clostridioides difficile (C. diff), is putting up a winning fight against hospital-grade disinfectants meant to kill it, reports a pharmacy professor in a study that helps explain why C. diff is so hard to eradicate. The survival of C. diff in hospitals and nursing homes is especially hazardous -- within one month of diagnosis, one in 11 people over age 65 died of a health care-associated C. diff infection.

The scientific evidence for these guidelines was evaluated using the Grading of Recommendations Assessment, Development, and Evaluation process. In instances where the evidence was not appropriate for Grading of Recommendations Assessment, Development, and Evaluation but there was consensus of significant clinical merit, key concept statements were developed using expert consensus. These guidelines are meant to be broadly applicable and should be viewed as the preferred, but not the only, approach to clinical scenarios....

Here are ways health care EVS workers can be well prepared for the next infectious situation beyond COVID-19.

Clindamycin, fluoroquinolones, and ceftriaxone are associated with the highest risk of CDI.

MDRO hot spots can be defined by distance from the patient and from wastewater reservoirs. Evaluating how MDROs are enriched relative to bacterial DNA deposition helps to identify healthcare micro-environments and suggests how targeted environmental cleaning or design approaches could prevent MDRO p …

Hospitalizations related to C. diff infections can cost more than twice as much as the average hospitalization and can extend patients’ stays by an average of 3.6 days.

A novel 4% hydrogen peroxide disinfectant was effective against methicillin-resistant Staphylococcus aureus (MRSA), Clostridioides difficile spores, carbapenem-resistant Escherichia coli, and 2 strains of Candida auris. In laboratory testing, a sodium hypochlorite disinfectant caused fading and loss …

Secondary OVP while receiving systemic antibiotics reduces the risk of recurrent CDI in pediatric patients with a history of CDI.

/PRNewswire/ -- Versatope Therapeutics, Inc., a biotechnology company developing vaccines and therapeutics, announced today that it has been awarded a Phase 1...

Nearly half of all never C difficile cases are found in nursing home communities.

There are no proven effective, evidenced-based prophylaxis options for primary CDI. As for secondary prevention, FMT is considered the option of choice in patients with multiple recurrences. Bezlotoxumab can be added to standard treatment for patients at high risk for R-CDI. The most promising strat …

Simon Mercer, director at Signo-Nanocare, looks at how antimicrobial technology applied through nano-coatings can be used to reduce the transfer of hospital acquired infections (HAI).

Sparing and Restoring the Gut Microbiota – A Collaborative Approach to Treating and Preventing Recurrent Clostridioides Diarrhea

As we move closer to herd immunity with COVID-19 through vaccination, it’s easy to become lax about habits like frequent handwashing. However, other germs abound, and some can be harmful, so keeping your hands clean as much as possible is paramount. But what’s the best method: handwashing or hand sanitizer? Soap and Water Benefits. Soap and water make quite the pair, working seamlessly to remove all types of germs and other harmful agents from your hands in just 20 seconds.

AJMC, July 6, 2021 (Audio)

The potential benefit of the administration of probiotics in children has been studied in many settings globally. Probiotics products contain viable micro-organisms that confer a health benefit on the host. Beneficial effects of selected probiotic strains for the management or prevention of selected …

Spore-forming bacteria are a major concern for the food industry as they cause both spoilage and food safety issues. Moreover, as they are more resistant than vegetative cells, their removal from the food processing environment may be difficult to achieve. This study investigated the efficacy of the …

Join our guests, Missy Travis, RN, and Priya Balachandran, Ph. D.

Only 5 patients treated with antibiotic prophylaxis developed bacteremia.

Your gut is a lively place. Bacteria of all kinds thrive in your intestines — and for the most part help you to thrive. "The gut microbiota is a very complex ecosystem," says Dr. Geoffrey Preidis…

Deborah T. writes:

A 3-strain Lactobacillus probiotic for primary prevention of Clostridioides difficile infection was ineffective in older patients receiving antibiotics.