C Diff Prevention

Hospital-onset clostridium difficile infections frequently occur because of both patient and environmental risk factors.

Aim: The objective of this study was to determine the effect of standard and candidate prebiotics on the adhesion and biofilm formation of Bacteroides sp. in monoculture and co-culture with Clostridioides difficile. Materials & methods: The effect of seven prebiotics …

The new hospital featured 50% private rooms, as well as regular cleaning and other preventative measures for C difficile infections.

Pathogen whole-genome sequencing has become an important tool for understanding the transmission and epidemiology of infectious diseases. It has improved our understanding of sources of infection and transmission routes for important healthcare-associated pathogens, including Clostridioides difficil …

Clostridioides difficile infection (CDI) is frequently associated with intestinal injury and mucosal barrier dysfunction, leading to an inflammatory response involving neutrophil localization and upregulation of pro-inflammatory cytokines. The severity of clinical manifestations is associated …

You are probably familiar with the idea that an altered gut microbiota composition has been linked to a wide range of intestinal and extraintestinal conditions. Learn more about what science says are the best ways to take care of your gut microbiota.

Intensive monitoring of ICU terminal room cleaning with an ATP modality is associated with a reduction of MDRO infection and colonization.

A sporicidal surface disinfection is recommended both for the outbreak and the endemic setting but a comparative evaluation on the efficacy of "sporicidal" surface disinfectants using suspension tests and 4-field tests has not been performed. We determined the efficacy of five "sporicidal" surface d …

Clostridioides difficile infections (CDIs) are the most common cause of acquired diseases in hospitalized patients. Effective surface disinfection, focused on the inactivation of the spores of this pathogen, is a decisive factor in reducing the number of nosocomial cases of CDI infections. An …

An abstract is unavailable.

Clinical stage outfit, Destiny Pharma, provides a positive summary of the year ahead

About 25% of C difficile infections are due to community spread.

Clinicians are finding that there really is no basis to recommend probiotics for patients with Clostridioides difficile infection, that instead they may cause harm, said Colleen R. Kelly, MD, FACG, gastroenterologist and associate professor of medicine at The Warren Alpert Medical School of Brown University.

Results from sampling healthcare surfaces for pathogens are difficult to interpret without understanding the factors that influence pathogen detection. We investigated the recovery of four healthcare-associated pathogens from three common surface materials, and how a body fluid simulant (artificial …

Although in children the incidence of HO-CDI is increasing, its clinical manifestation is still milder and effective infection control measures with antibiotic stewardship can limit related morbidly, mortality, LOS, and cost.

Abstract Background: Clostridioides difficile infection (CDI) is a common and sometimes life-threatening illness. Patient-, care-, and room hygiene-specific factors are known to impact CDI genesis, but care provider training and room topography have not been explored. We …

Infections with multi-drug resistant microorganisms associated with the provision of health services have become an acute problem worldwide. These infections cause increased morbidity as well as mortality and are a financial burden for the healthcare system. Effective risk management can reduce the …

The Nocospray Disinfection System has a full spectrum of activity against bacteria, viruses, and is a proven sporicidal #Cdiff. https://t.co/R6mv3smdeL #HAI #disinfection @jjur68 @dnice1946 @JoanneOliverON @CindyFrank63 @FredFriedberg1 @JuliePaquet13v #COVID19AB #covid19nfld pic.twitter.com/5wVBKjtQoO— NocoSpray Canada (@NocospraySystem) January 10, 2022

Efforts to address high rates of infection and deaths will have the best chances of success if there are concurrent efforts to address larger issues.

Ten c-RCTs focused on reducing multiple MDROs and/or HAIs and four had significant reductions. Three c-RCTs reported only patient MRSA colonization rates (one significant reductions), and one focused on Clostridioides difficile (no significant differences). Standardised primary and secondary outcome …

Non-compliance with hand hygiene among members of medical staff contributes to nosocomial infections which are a major cause of disease complications and deaths. Proper hand hygiene is a key measure for reducing this phenomenon. In every medical institution, especially in hospitals, and staff should …

Clinical Care Options (CCO) commentary from Dr. Kevin Garey on new data on the patient and economic burden of Clostridioides difficile presented at IDWeek 2021

E. lactis JDM1 is expected to be developed as a probiotic, and its probiotic properties are worthy of further exploration.

Non-compliance with hand hygiene among members of medical staff contributes to nosocomial infections which are a major cause of disease complications and deaths. Proper hand hygiene is a key measure for reducing this phenomenon. In every medical institution, especially in hospitals, and staff should …

Hospital-onset CDI rates dropped by 6% in the first quarter of the program, which launched in 2016.

Solutions being explored include modified hand sanitizers, microbiome-based therapeutics, solutions for detecting contaminated surfaces, and more.

To evaluate changes in Clostridioides difficile incidence rates for Maryland hospitals that participated in the Statewide Prevention and Reduction of C. difficile (SPARC) collaborative. Pre-post, difference-in-difference analysis of non-randomised intervention using four quarters of pr …

The current guidelines suggest that hospital rooms previously occupied with Clostridioides difficile infection (CDI) patients should be decontaminated with recommended decontamination methods because C. difficile can persist on surfaces despite adherence to the recommended procedures. Recently, ultr …