A large number of studies on CDI prevalence in humans from the Middle and the Far East have been published; countries with no available data were identified. The number of studies on C. difficile from non-human sources is limited. Comparative genomic studies of isolates from different sources are ne …

The idea of treating psychiatric disorders with another person's poo is gaining traction in research and clinical circles. But how does it work and what do we need to know before it can be widely used to mend minds?

In Spain, the prevalence rate of both HA-CDI and CA-CDI have been increasing. Burden of CDI as well as clinical and epidemiological characteristics of CDI patients will help to support public health decision-making.

Surfaces with high levels of ATP and crAssphage were identified. Quantifying levels of contamination longitudinally and before and after cleaning might enhance infection prevention and control procedures for reducing diarrheal illnesses in LTC facilities.

Clostridioides difficile is the leading cause of infectious diarrhea and one of the most common healthcare-acquired infections worldwide. We performed a systematic search and a bibliometric analysis of mathematical and computational models for Clostridioides difficile transmission. We identified 33 …

Here, we evaluated the frequency of C. difficile colonization and its impact on clinical outcomes in patients admitted to intensive care units in Brazil. From ninety-two patients screened 16 (17.3%) were colonized by C. difficile. Colonized patients had higher Simplified Acute Physiology Score III ( …

Vancomycin-resistant Clostridium innocuum was recently identified as an etiologic agent for antibiotic-associated diarrhea in humans. We conducted a case-control study involving 152 C. innocuum-infected patients during 2014-2019 in Taiwan, using 304 cases of Clostridioides difficile infection (CDI) …

This study adds further evidence that hospital environment in patient rooms may contribute to risk for CDI.

This large surveillance study of several countries demonstrated high prevalence of toxigenic C. difficile in non-healthcare environments with high contamination rates from floors and shoe soles.

To provide a detailed review of literary studies identifying the prevalence of nosocomial infections & antibiotic-resistant in Middle Eastern countries.

Clostridioides difficile is the predominant pathogen responsible for antimicrobial associated diarrhea (AAD) and health care facility-associated infectious diarrhea. The role of C. difficile in China and its impact on public health have gained attention in recent years. Most clinical C. difficile is …

An increase in pediatric cases of C difficile is linked to use of broad-spectrum antibiotics, recurrent infections, and a growth in highly virulent strains.

In a study of 11 LTC facilities, these surfaces were 4 times more likely to register high levels of crAssphage and adenosine triphosphate (ATP).

More than 90% of "high-touch" surfaces in long-term care facilities are contaminated with fecal matter and other potential sources of infectious disease spread, a study found.

3,5 years of #research highlight important knowledge gaps on the scale of #Cdiff #infections and the many uncounted #CDI cases in the community due to a lack of 'clinical suspicion'. See more preliminary results in our infographic. https://t.co/eMhQQxsagt https://t.co/AQ6iZQNuI3— COMBACTE (@COMBACTE) February 8, 2022

Relocation to a new hospital significantly reduced HO-CDI incidence, concomitantly decreasing the incidence of CO-CDI, potentially due to environmental improvements.

The new hospital featured 50% private rooms, as well as regular cleaning and other preventative measures for C difficile infections.

Data concerning Clostridium difficile infection severity and prognosis in Portugal is scarce, and future studies should focus on this important topic.

To reduce antimicrobial resistant pathogens, nursing homes should carefully monitor their use of hospital-grade antibiotics.

C. difficile colonisation among children ages 0-2 years was variable across low-resource settings. Significant elevation of intestinal inflammation and barrier disruption markers associated with C. difficile detection suggests subclinical impact of colonisation.

The COMBACTE-CDI results highlight key differences between community and hospital CDI across Europe in terms of diagnosis, risks and outcomes; important factors to understand if we are to try and improve patient care. The project is still in progress with a number of key outputs still to be completed.

While many studies have used ML to investigate CDI or CDI outcomes, electronic phenotyping of CDI was uncommon and phenotype validation was not reported in any study. Methodological approaches were heterogeneous. Validating CDI electronic phenotypes, evaluating performances of CDI models during a si …

The independent risk factors for CDI were: hospital admission in the 4 weeks prior to infection, hypoalbuminemia, and previous administration of antibiotics. Fever and hospitalization in the previous 4 weeks were also identified as prognostic factors of unfavourable evolution.

While the fight to prevent the spread of COVID-19 continues, a dangerous public health crisis is emerging for a different reason. Various stresses on the healthcare system resulting from the pandemic have opened the door to a host of potentially increased occasions of cross-contamination from dangerous pathogens.

Background: Antibiotic-resistant and antibiotic-associated pathogens are commonly encountered by surgeons. Pathogens such as methicillin-resistant Staphylococcus aureus (MRSA), Clostridioides difficile infection (CDI), and carbapenem-resistant Enterobacteriaceae (C …

It was a pleasure to meet with Dr Jinhee Jo (Department of Pharmacy Practice and Translational Research, University of Houston, Houston, TX, USA) to discuss her study investigating the understanding of how C. Difficile is transmitted, and who it affects. The abstract entitled: ‘Global Surveillance of Clostridioides difficile Demonstrates High Prevalence in Non-Healthcare Settings’ was […]

For a study, it was determined that the elderly in nursing homes (NHs) were disproportionally affected by Clostridioides difficile. The study aimed to look at...

Anaerobe. 2022 Jan 18:102518. doi: 10.1016/j.anaerobe.2022.102518. Online ahead of print.ABSTRACTThe ongoing coronavirus disease (COVID-19) pandemic has