We describe a case of interspecies transmission of toxigenic Clostridioides difficile involving a female and her dog, both with diarrhea without another diagnosis. Genomic analysis showed that isolates were grouped into MLST clade I, closely related to ribotype 020 and shared identical genotypes.

The ongoing coronavirus disease (COVID-19) pandemic has dramatically tested healthcare systems around the world, with serious repercussions on the measures of prevention and control of hospital-acquired infections (HAIs). Among HAIs, Clostridioides difficile infection (CDI) represents one of the mos …

Clostridioides difficile infection (CDI) continues to affect hospitalized patients and community populations worldwide. In contrast to the substantial resources invested in the diagnosis and prevention of CDI in high-income countries, this anaerobic toxigenic bacterium has been largely overlooked in …

Anaerobe. 2022 Jan 18:102518. doi: 10.1016/j.anaerobe.2022.102518. Online ahead of print.ABSTRACTThe ongoing coronavirus disease (COVID-19) pandemic has

Epidemiological analyses of mandatory surveillance data on healthcare associated infections (HCAI); MRSA, MSSA and Gram-negative bacteraemia (Escherichia coli (E. coli), Pseudomonas aeruginosa ( P. aeruginoa), Klebsiella species (Klebsiella spp.)), and Clostridioides difficile (C. difficile) infection.

A two-step typing method could rapidly confirm species identification and define the toxin gene profile of C. difficile isolates. The clonal expansion of RT127 strains in Taiwan indicates monitoring and surveillance of toxigenic C. difficile isolates from human, animal, and environment are critical …

Clostridioides difficile is the leading cause of healthcare-associated infectious diarrhoea. However, it is increasingly appreciated that healthcare-associated infections derive from both community and healthcare environments, and that the primary sites of C. difficile transmission may …

The cutting-edge research identifies weaknesses in dangerous C. difficile bacteria.

Clostridioides difficile, which causes life-threatening diarrheal disease, presents an urgent threat to health care systems. In this study, we present a retrospective genomic and epidemiological analysis of C. difficile in a large teaching hospital. First, we collected 894 nonduplicate fecal samples …

Patients who receive a solid organ transplant and develop CDI are at an increased risk for an acute kidney injury.

Clostridioides (Clostridium) difficile presents a significant health risk to humans and animals. The complexity of the bacterial-host interaction affecting pathogenesis and disease development creates an ongoing challenge for epidemiological studies, control strategies and prevention planning. The r …

Nature Metabolism - How pathogens induce life-threatening symptoms in some individuals but not others is one of the greatest puzzles in biology. Pruss et al. have discovered that the presence of...

The single-center study suggested shoes are a common transmission route, but also hinted at a diverse web of transmission involving humans, animals, and the environment.

We reviewed the molecular epidemiology of Clostridioides difficile infection (CDI) in Japan by reviewing articles in which typing analysis was performed on recovered C. difficile isolates. Most of the multicenter studies showed that the major prevalent PCR-ribotypes (RT018-related type, RT014, RT002 …

The opportunistic intestinal pathogen Clostridioides difficile is the number one cause of nosocomial diarrhea in humans. In this study, C. difficile was isolated from 26.7% of potatoes and 1.9% of salads from German retail. The majority of strains possessed toxinogenic PCR-ribotypes that are associa …

Clostridioides difficile has been identified as one of the primary etiologic agents of nosocomial diarrhea and pseudomembranous colitis in humans and other mammals associated following broad-spectrum antibiotics use. In Rio de Janeiro, Brazil we describe a case of C. difficile infection (CDI) in a 1 …

One adaptation to extreme heat events is the installation of air conditioning (along with heating and ventilation) in homes and public buildings across the world.

Critically ill patients in EICU routinely use PPI and antibiotics, and the use of antibiotics does not affect the CD positive rate. The independent risk factors of CDI/CDC are the APACHE II score and the duration of hospitalization, but fecal CD positive has no obvious influence on death.

Clostridioides difficile infection (CDi) is one of the foremost hospital-acquired infections. We present an observational study aimed to describe the incidence, epidemiology, and clinical outcome of CDi in a tertiary university hospital in Buenos Aires. The episodes, diagnosed in 117 consecutive adu …

Identifying CDI: Presentation, Prevalence, and Spectrum of Disease - Pharmacy Times https://t.co/e9FxNWBHSS #cdi #cdiff— Dave Roberts (@CDifficile1) November 30, 2021

Small, diffusible second messenger molecules transmit information about extracellular conditions to intracellular machinery in order to influence tran…

NewsDesk  @infectiousdiseasenews Scientists around the world have been working in earnest to improve understanding of an increasingly virulent superbug, Clostridioides difficile. The highly contagious hospital-acquired pathogen, designated by the Centers for Disease Control and Prevention as one of the five most urgent threats to the U.S. healthcare system, causes more than 500,000 infections and 29,000 deaths each year at […]

These findings suggest developing community-based infection prevention and control strategies could significantly lower rates of CDI in the hospital setting.

Intestinal infections were reported in 14.9% of patients (102/685) with IBD symptoms. Positive test results for C. difficile toxins A and B and rectal swab cultures among patients without IBD symptoms were reported in 35.7% of cases (281/786). Intestinal superinfections may complicate the clinical p …

Aims To investigate if Clostridium (Clostridioides) difficile infection (CDI), traditionally thought of as hospital-acquired, can be genomically linked to hospital or community environmental sources...

Clostridium difficile or C. diff – a bacteria that causes inflammation of the colon and severe diarrhea – is widely prevalent in non-healthcare settings in the United States and around the world, according to University of Houston researchers who presented at IDWeek.

The use of almost every antibiotic increases the chances of Clostridioides difficile infection, and that includes the drugs that are used to treat C diff, a study states.

Teena Chopra, MD, MPH, professor of infectious diseases at Wayne State University, discussed the current burden of C. diff infection and recurrent C. diff infection.

(1) Background: Firefighters spend about 64% of their time responding to medical emergencies and providing medical care without a patient history, which can render them vulnerable to healthcare-associated infections (HAI). Infection prevention, control, and surveillance systems have been instituted …